Gleicy Gabriela Vitória Spínola Carneiro Falcão1, Viviane Almeida Sarmento1, Brenda Soares Dutra2, Bruno Russoni2, Letycia Santos de Oliveira1, Dayana Alves Costa2, Carlos Brites2, Jerry E Bouqout3, Liliane Lins-Kusterer4,5. 1. School of Dentistry, Federal University of Bahia, Salvador, Bahia, Brazil. 2. Postgraduate Program in Medicine and Health, School of Medicine, Federal University of Bahia, Bahia, Brazil. 3. Department of Diagnostic Sciences, School of Dentistry, University of Texas, Houston, TX, USA. 4. Postgraduate Program in Medicine and Health, School of Medicine, Federal University of Bahia, Bahia, Brazil. lkusterer@gmail.com. 5. Programa de Pós-Graduação em Medicina e Saúde, Faculdade de Medicina da Bahia, Programa de Pós-Graduação em Medicina e Saúde, Faculdade de Medicina da Bahia, Rua Doutor Augusto Viana, s/n - Canela, Salvador, BA, 40110-060, Brazil. lkusterer@gmail.com.
Abstract
OBJECTIVE: To compare the oral health status and oral health-related quality of life (OHRQoL) in symptomatic and asymptomatic patients with human T-cell leukemia virus-1 (HTLV-1). MATERIAL AND METHODS: This cross-sectional study included 204 seropositive patients, classified into two groups, symptomatic and asymptomatic. The first group included patients with neurological symptoms associated with HTLV-1 (n = 69), and the second group, asymptomatic HTLV-1 carriers (n = 135). We evaluated the total unstimulated saliva flow, oral mucosa, the Decayed, Missing, Filled Teeth (DMFT) index, and Periodontal Screening and Recording (PSR). The Oral Health Impact Profile (OHIP14) measured the oral health-related quality of life. General health-related quality of life was measured by the 36-Item Short-Form Health Survey (SF-36). Variables with a value of p < 0.25 in bivariate analysis were selected, together with SF-36 summaries' scores and total OHIP-14, for composing a logistic regression model that had symptomatology as the dependent variable. RESULTS: The OHIP-14 total score was poor in symptomatic and asymptomatic groups, but with no marked difference between them. Symptomatic patients showed significantly lower SF-36 scores (P ≤ 0.05) compared to asymptomatic ones, except for mental component summary (MCS). Family income (1-2.99 minimal wages), reduced salivary flow, flossing, and lower physical component summary (PCS) were associated (P ≤ 0.05) with symptomatology. CONCLUSIONS: Symptomatic individuals living with HTLV-1 showed lower HRQoL and poorer OHRQoL compared to asymptomatic ones. Family income, flossing, reduced salivary flow, and lower PCS were associated with symptomatic HTLV-1 individuals. CLINICAL RELEVANCE: In the present study, symptomatic individuals with HTLV-1 showed higher family income, poorer oral health status, lower salivary flow, poorer OHRQoL, and lower HRQoL compared to asymptomatic ones.
OBJECTIVE: To compare the oral health status and oral health-related quality of life (OHRQoL) in symptomatic and asymptomatic patients with human T-cell leukemia virus-1 (HTLV-1). MATERIAL AND METHODS: This cross-sectional study included 204 seropositive patients, classified into two groups, symptomatic and asymptomatic. The first group included patients with neurological symptoms associated with HTLV-1 (n = 69), and the second group, asymptomatic HTLV-1 carriers (n = 135). We evaluated the total unstimulated saliva flow, oral mucosa, the Decayed, Missing, Filled Teeth (DMFT) index, and Periodontal Screening and Recording (PSR). The Oral Health Impact Profile (OHIP14) measured the oral health-related quality of life. General health-related quality of life was measured by the 36-Item Short-Form Health Survey (SF-36). Variables with a value of p < 0.25 in bivariate analysis were selected, together with SF-36 summaries' scores and total OHIP-14, for composing a logistic regression model that had symptomatology as the dependent variable. RESULTS: The OHIP-14 total score was poor in symptomatic and asymptomatic groups, but with no marked difference between them. Symptomatic patients showed significantly lower SF-36 scores (P ≤ 0.05) compared to asymptomatic ones, except for mental component summary (MCS). Family income (1-2.99 minimal wages), reduced salivary flow, flossing, and lower physical component summary (PCS) were associated (P ≤ 0.05) with symptomatology. CONCLUSIONS: Symptomatic individuals living with HTLV-1 showed lower HRQoL and poorer OHRQoL compared to asymptomatic ones. Family income, flossing, reduced salivary flow, and lower PCS were associated with symptomatic HTLV-1 individuals. CLINICAL RELEVANCE: In the present study, symptomatic individuals with HTLV-1 showed higher family income, poorer oral health status, lower salivary flow, poorer OHRQoL, and lower HRQoL compared to asymptomatic ones.
Authors: Ana Verena Galvão-Castro; Ney Boa-Sorte; Ramon Almeida Kruschewsky; Maria Fernanda Rios Grassi; Bernardo Galvão-Castro Journal: Qual Life Res Date: 2011-11-23 Impact factor: 4.147
Authors: Gustavo Pompermaier Garlet; Silvana Pereira Giozza; Elcia Maria Silveira; Marcela Claudino; Silvane Braga Santos; Mario Julio Avila-Campos; Walter Martins; Cristina Ribeiro Cardoso; Ana Paula Favaro Trombone; Ana Paula Campanelli; Edgar Marcelino Carvalho; João Santana Silva Journal: Clin Infect Dis Date: 2010-02-01 Impact factor: 9.079