PURPOSE: A previous study found the prevalence of depression in HTLV-1-infected patients to be approximately 30%, but few studies have attempted to correlate depression with quality of life (QOL) in these patients. The present study investigates the association between depression and QOL in people living with HTLV-1. METHODS: A clinical-epidemiological questionnaire, the Mini International Neuropsychiatric Interview and the WHOQOL-Bref were applied to 88 HTLV-1-infected patients (32 with TSP/HAM) at the HTLV Center of the Bahiana School of Medicine and Public Health, Salvador, Brazil. RESULTS: The prevalence of depression among people living with HTLV-1 was 34.1%. Depression was significantly associated with a poor QOL in the physical, psychological, social relationship and environment domains, when controlling for other variables, such as gender, age, time of knowledge of serological diagnosis and presence of tropical spastic paraparesis/HTLV-1associated myelopathy (TSP/HAM). Moreover, patients with TSP/HAM experienced a reduction in their QOL in the physical, psychological and environment domains. CONCLUSION: Our results showed that depression negatively affects the quality of life of people living with HTLV-1, regardless of the presence of TSP/HAM. Since it is possible to improve a patient's QOL by treating depression, psychological evaluations are strongly recommended as a measure to integrate the treatment protocols of HTLV-1 intervention programs.
PURPOSE: A previous study found the prevalence of depression in HTLV-1-infectedpatients to be approximately 30%, but few studies have attempted to correlate depression with quality of life (QOL) in these patients. The present study investigates the association between depression and QOL in people living with HTLV-1. METHODS: A clinical-epidemiological questionnaire, the Mini International Neuropsychiatric Interview and the WHOQOL-Bref were applied to 88 HTLV-1-infectedpatients (32 with TSP/HAM) at the HTLV Center of the Bahiana School of Medicine and Public Health, Salvador, Brazil. RESULTS: The prevalence of depression among people living with HTLV-1 was 34.1%. Depression was significantly associated with a poor QOL in the physical, psychological, social relationship and environment domains, when controlling for other variables, such as gender, age, time of knowledge of serological diagnosis and presence of tropical spastic paraparesis/HTLV-1associated myelopathy (TSP/HAM). Moreover, patients with TSP/HAM experienced a reduction in their QOL in the physical, psychological and environment domains. CONCLUSION: Our results showed that depression negatively affects the quality of life of people living with HTLV-1, regardless of the presence of TSP/HAM. Since it is possible to improve a patient's QOL by treating depression, psychological evaluations are strongly recommended as a measure to integrate the treatment protocols of HTLV-1 intervention programs.
Authors: Carlos M De Castro-Costa; Abelardo Q C Araújo; Márcio M Barreto; Osvaldo M Takayanagui; Marzia P Sohler; Eduardo L M da Silva; Sônia M B de Paula; Ricardo Ishak; João G R Ribas; Luis C Rovirosa; Herwig Carton; Eduardo Gotuzzo; William W Hall; Silvia Montano; Edward L Murphy; Joel Oger; Carlos Remondegui; Graham P Taylor Journal: AIDS Res Hum Retroviruses Date: 2006-10 Impact factor: 2.205
Authors: B Galvão-Castro; L Loures; L G Rodriques; A Sereno; O C Ferreira Júnior; L G Franco; M Muller; D A Sampaio; A Santana; L M Passos; F Proietti Journal: Transfusion Date: 1997-02 Impact factor: 3.157
Authors: E S Azevêdo; C M Fortuna; K M Silva; M G Sousa; M A Machado; A M Lima; M E Aguiar; K Abé; M C Eulálio; M M Conceição; M C Silva; M G Santos Journal: Hum Biol Date: 1982-05 Impact factor: 0.553
Authors: Bernardo Galvão-Castro; Maria Fernanda Rios Grassi; Ana Verena Galvão-Castro; Aidê Nunes; Ana Karina Galvão-Barroso; Thessika Hialla Almeida Araújo; Regina Helena Rathsam-Pinheiro; Ceuci Lima Xavier Nunes; Adriele Ribeiro; Monique Lírio; Noilson Lázaro Gonçalves; Sônia Lúcia Rangel; Cristiane Maria Carvalho Costa Dias; Daniele Piai Ozores; Selena Márcia Dubois-Mendes; Isabela Lima; André Luís Pereira Silva; Washington Luiz Abreu de Jesus; Fred Luciano Neves Santos; José Guilherme Reis de Oliveira; Yscela Vanessa Pimentel de Moraes; Adijeane Oliveira de Jesus; Francisco Daltro; Ney Boa-Sorte; Humberto Castro-Lima; Maria Luísa Carvalho Soliani Journal: Front Med (Lausanne) Date: 2022-06-07
Authors: Glória O Orge; Thais R Dellavechia; José Abraão Carneiro-Neto; Lucas Araújo-de-Freitas; Carla H C Daltro; Carlos T Santos; Lucas C Quarantini Journal: PLoS One Date: 2015-05-27 Impact factor: 3.240
Authors: Carolina Rosadas; Tatiane Assone; Marina Yamashita; Adine Adonis; Marzia Puccioni-Sohler; Marisa Santos; Arthur Paiva; Jorge Casseb; Augusto C P Oliveira; Graham P Taylor Journal: PLoS Negl Trop Dis Date: 2020-10-16
Authors: Ricardo Henrique-Araújo; Lucas C Quarantini; André C Caribé; Felipe C Argolo; Ana Paula Jesus-Nunes; Mychelle Morais-de-Jesus; Adriana Dantas-Duarte; Tayne Miranda Moreira; Irismar Reis de Oliveira Journal: Braz J Infect Dis Date: 2019-07-22 Impact factor: 3.257