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Literature DB >> 3463566

Tentative disk diffusion susceptibility interpretive criteria for pefloxacin.

P C Fuchs, A L Barry, R N Jones, C Thornsberry.

Abstract

Standardized broth microdilution and disk diffusion susceptibility tests for pefloxacin were performed on 585 clinical isolates. The 5-micrograms pefloxacin disk is recommended, and the following breakpoints are proposed: susceptible, greater than or equal to 19 mm (MIC, less than or equal to 2.0 micrograms/ml); resistant, less than or equal to 15 mm (MIC, greater than 4.0 micrograms/ml); and intermediate, 16 to 18 mm.

Entities: Chemical

Mesh：

Substances：
Pefloxacin
Norfloxacin

Year: 1986 PMID： 3463566 PMCID： PMC268932 DOI： 10.1128/jcm.24.3.448-450.1986

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

5 in total

1. Norfloxacin (MK-0366, AM-715): in vitro activity and cross-resistance with other organic acids including quality control limits for disk diffusion testing.

Authors: R N Jones; A L Barry
Journal: Diagn Microbiol Infect Dis Date: 1983-06 Impact factor: 2.803

2. In-vitro activity of pefloxacin compared with six other quinolones.

Authors: E E Ligtvoet; T Wickerhoff-Minoggio
Journal: J Antimicrob Chemother Date: 1985-10 Impact factor: 5.790

3. Absorption, distribution, metabolic fate, and elimination of pefloxacin mesylate in mice, rats, dogs, monkeys, and humans.

Authors: G Montay; Y Goueffon; F Roquet
Journal: Antimicrob Agents Chemother Date: 1984-04 Impact factor: 5.191

4. In-vitro activity of pefloxacin compared to enoxacin, norfloxacin, gentamicin and new beta-lactams.

Authors: A M Clarke; S J Zemcov; M E Campbell
Journal: J Antimicrob Chemother Date: 1985-01 Impact factor: 5.790

5. Penetration of pefloxacin into cerebrospinal fluid of patients with meningitis.

Authors: M Wolff; B Regnier; C Daldoss; M Nkam; F Vachon
Journal: Antimicrob Agents Chemother Date: 1984-09 Impact factor: 5.191

5 in total

3 in total

Tentative disk diffusion susceptibility interpretive criteria for pefloxacin.

1. Norfloxacin (MK-0366, AM-715): in vitro activity and cross-resistance with other organic acids including quality control limits for disk diffusion testing.

2. In-vitro activity of pefloxacin compared with six other quinolones.

3. Absorption, distribution, metabolic fate, and elimination of pefloxacin mesylate in mice, rats, dogs, monkeys, and humans.

4. In-vitro activity of pefloxacin compared to enoxacin, norfloxacin, gentamicin and new beta-lactams.

5. Penetration of pefloxacin into cerebrospinal fluid of patients with meningitis.

1. Temafloxacin disk potency and tentative interpretive criteria for susceptibility tests.

Review 2. Pharmacokinetics of quinolones: newer aspects.

Review 3. Fluoroquinolone antimicrobial agents.