Literature DB >> 34629367

Evaluation of the genetic damage to workers in a Greek shipyard.

Dimitrios Koutsoumplias1, Artemis Damati1, Efthymios Thanasias2, Dimitris Vlastos3, George Halkos4, Demetrios Matthopoulos3, Vasilios Makropoulos2.   

Abstract

Shipyards are industrial areas where workers are likely exposed to environmental pollutants such as welding fumes, fine organic solvent and dye dust, that render the occupational environment a high risk one. Assessing the risk that workers are exposed to is a high critical factor in improving their working conditions. The present study aims to investigate the potential genetic damage to workers exposed to a harsh environment in a Greek shipyard. It is focused on assessing the percentage of induced micronuclei, as well as on changes in the various cell types of shipyard workers' oral mucosa epithelium by implementing the buccal micronucleus cytome assay. Exposed workers appeared with statistically significant induced micronuclei as compared to office employees. Statistically, significant cell lesions were detected and are related to workers' exposure to environmental conditions. The workers' smoking habit contributed as well to the observed buccal epithelial cell alterations. The observed data signify the high-risk workers are exposed; resulting in the shipyard's management the need to implement measures improving the working environment conditions and to reevaluate the workers' personal protective equipment requirements.

Entities:  

Keywords:  Buccal micronucleus assay; Dye dust; Micronuclei induction; Occupational exposure; Organic solvents; Smoking habit; Welding fumes

Mesh:

Year:  2021        PMID: 34629367      PMCID: PMC8825766          DOI: 10.2486/indhealth.2021-0024

Source DB:  PubMed          Journal:  Ind Health        ISSN: 0019-8366            Impact factor:   2.179


  87 in total

1.  Elevated blood lead levels and cytogenetic markers in buccal epithelial cells of painters in India: genotoxicity in painters exposed to lead containing paints.

Authors:  Mohd Imran Khan; Iqbal Ahmad; Abbas Ali Mahdi; Mohd Javed Akhtar; Najmul Islam; Mohd Ashquin; Thuppil Venkatesh
Journal:  Environ Sci Pollut Res Int       Date:  2010-03-19       Impact factor: 4.223

2.  Assessment of DNA damage in welders using comet and micronucleus assays.

Authors:  İldeniz Aksu; Hatice Gül Anlar; Gökçe Taner; Merve Bacanlı; Servet İritaş; Engin Tutkun; Nursen Basaran
Journal:  Mutat Res       Date:  2018-11-19       Impact factor: 2.433

3.  Biomonitoring of genotoxic effects among shielded manual metal arc welders.

Authors:  Sellappa Sudha; Subhadra Keyan Kripa; Prathyumnan Shibily; Shyn Joseph; Vellingiri Balachandar
Journal:  Asian Pac J Cancer Prev       Date:  2011

4.  Carcinogenicity of welding, molybdenum trioxide, and indium tin oxide.

Authors:  Neela Guha; Dana Loomis; Kathryn Z Guyton; Yann Grosse; Fatiha El Ghissassi; Véronique Bouvard; Lamia Benbrahim-Tallaa; Nadia Vilahur; Karen Muller; Kurt Straif
Journal:  Lancet Oncol       Date:  2017-04-10       Impact factor: 41.316

Review 5.  Smoking and smokeless tobacco-associated human buccal cell mutations and their association with oral cancer--a review.

Authors:  Nicole K Proia; Geraldine M Paszkiewicz; Maureen A Sullivan Nasca; Gail E Franke; John L Pauly
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2006-06       Impact factor: 4.254

6.  Micronuclei frequencies and nuclear abnormalities in oral exfoliated cells of nuclear power plant workers.

Authors:  Shitalkumar G Sagari; Roopa Babannavar; Abhishek Lohra; Ashwin Kodgi; Sunil Bapure; Yogesh Rao; Arun J; Manjunath Malghan
Journal:  J Clin Diagn Res       Date:  2014-12-05

7.  Multiple biomarkers study in painters in a shipyard in Korea.

Authors:  Kyoung-Ho Lee; Masayoshi Ichiba; Jiusong Zhang; Katsumaro Tomokuni; Yun-Chul Hong; Mina Ha; Ho Jang Kwon; Sang-Back Koh; Hong-Ryul Choi; Kwan-Hee Lee; Chung-Gyu Park; Soo-Hun Cho; Ari Hirvonen; Paul T Strickland; Roel Vermeulen; Richard B Hayes; Daehee Kang
Journal:  Mutat Res       Date:  2003-09-09       Impact factor: 2.433

8.  Mortality in two cohorts of welders exposed to high- and low-levels of hexavalent chromium.

Authors:  B Sjögren; A Gustavsson; L Hedström
Journal:  Scand J Work Environ Health       Date:  1987-06       Impact factor: 5.024

9.  Occupational risk assessment of paint industry workers.

Authors:  Hugo M de Oliveira; Gracilene P Dagostim; Arielle Mota da Silva; Priscila Tavares; Luiz A Z C da Rosa; Vanessa M de Andrade
Journal:  Indian J Occup Environ Med       Date:  2011-05

10.  Exposure to welding fumes increases lung cancer risk among light smokers but not among heavy smokers: evidence from two case-control studies in Montreal.

Authors:  Eric Vallières; Javier Pintos; Jérôme Lavoué; Marie-Élise Parent; Bernard Rachet; Jack Siemiatycki
Journal:  Cancer Med       Date:  2012-06-07       Impact factor: 4.452

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