Literature DB >> 3462726

Synthesis of coenzyme A ester of retinoic acid: intermediate in vitamin A metabolism.

A Kutner, B Renstrom, H K Schnoes, H F DeLuca.   

Abstract

Coenzyme A esters of all-trans- and 13-cis-retinoic acid were synthesized for use in studying vitamin A metabolism. The esters were obtained by two different synthetic methods starting from retinoic acids, which were converted to activated succinimidyl esters or anhydrides. These in turn were coupled with coenzyme A to form their respective thioesters. The retinoyl coenzyme A esters were purified by reverse-phase high performance liquid chromatography.

Entities:  

Mesh:

Substances:

Year:  1986        PMID: 3462726      PMCID: PMC386593          DOI: 10.1073/pnas.83.18.6781

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  6 in total

1.  A convenient and versatile method for the purification of CoA thiol esters.

Authors:  M E Pullman
Journal:  Anal Biochem       Date:  1973-07       Impact factor: 3.365

2.  A new method for the preparation of acyl-CoA thioesters.

Authors:  A Kawaguchi; T Yoshimura; S Okuda
Journal:  J Biochem       Date:  1981-02       Impact factor: 3.387

3.  Activation of retinoic acid by coenzyme A for the formation of ethyl retinoate.

Authors:  D A Miller; H F DeLuca
Journal:  Proc Natl Acad Sci U S A       Date:  1985-10       Impact factor: 11.205

4.  The biological activity of cyclopropyl analogs of all-trans- and 13-cis-retinoic acid in the rat vaginal smear assay.

Authors:  R W Curley; D P Silva; H F DeLuca
Journal:  Arch Biochem Biophys       Date:  1985-05-01       Impact factor: 4.013

5.  Preparation, properties and metabolism of retinoic acid anhydride.

Authors:  B R Premachandra; H R Cama
Journal:  Int J Vitam Nutr Res       Date:  1975       Impact factor: 1.784

6.  Metabolism of retinoic acid in vivo in the vitamin A-deficient rat.

Authors:  D P Silva; H F DeLuca
Journal:  Biochem J       Date:  1982-07-15       Impact factor: 3.857

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.