| Literature DB >> 34626372 |
Robert V Williams1, I Jonathan Amster2.
Abstract
Traveling wave ion-mobility mass spectrometry (TWIMS) combined with native mass spectrometry (MS) has emerged as a powerful tool for analyzing biomolecules, including complexes of protein and heparan sulfate (HS). This technique allows determination of the stoichiometry of the protein-HS interaction and information on the overall 3D molecular envelope.Entities:
Keywords: Heparan sulfate; Native mass spectrometry; Protein–glycosaminoglycan interactions; Traveling wave ion mobility
Mesh:
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Year: 2022 PMID: 34626372 DOI: 10.1007/978-1-0716-1398-6_8
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745