Jinjia Zhang1, Jinxin Zhang2, Huadong Wu3, Rongying Wang4. 1. Department of General Practice, Second Hospital of Hebei Medical University, Heping Western Road No. 215, Shijiazhuang, 050000, Hebei, China. 2. Department of Neurology, Weixian People's Hospital, Weixian, Xingtai, 054700, Hebei, China. 3. Department of Gastrointestinal Surgery, Second Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China. 4. Department of General Practice, Second Hospital of Hebei Medical University, Heping Western Road No. 215, Shijiazhuang, 050000, Hebei, China. wangrongying2017@sina.com.
Abstract
PURPOSE: Current studies indicate that the association between sleep duration and risk of hyperlipidemia is uncertain. This systematic review aimed to evaluate relevant prospective studies and make a definite conclusion. METHODS: Three databases were searched for prospective studies on the relationship between sleep duration and hyperlipidemia risk from their inception to October 2020. RESULTS: We identified twelve studies involving 114,439 participants. Follow-up for incident hyperlipidemia ranged from 200 days to 10 years. Neither long (RR:1.00, 95%CI:0.90-1.11, P > 0.05) nor short (RR:0.99, 95%CI:0.94-1.05, P > 0.05) sleep duration had a significant association with increased hyperlipidemia risk in adults. However, long sleep duration was decidedly associated with low HDL-C (RR:0.19, 95%CI: - 0.03-0.40, P < 0.05) and high triglycerides (RR: - 0.20, 95%CI: - 0.43-0.03, P < 0.05) in children and adolescents. CONCLUSION: Long sleep duration has strong associations with risks of low HDL-C and high triglycerides in children and adolescents. The mechanisms underlying this association deserves to be explored in future studies.
PURPOSE: Current studies indicate that the association between sleep duration and risk of hyperlipidemia is uncertain. This systematic review aimed to evaluate relevant prospective studies and make a definite conclusion. METHODS: Three databases were searched for prospective studies on the relationship between sleep duration and hyperlipidemia risk from their inception to October 2020. RESULTS: We identified twelve studies involving 114,439 participants. Follow-up for incident hyperlipidemia ranged from 200 days to 10 years. Neither long (RR:1.00, 95%CI:0.90-1.11, P > 0.05) nor short (RR:0.99, 95%CI:0.94-1.05, P > 0.05) sleep duration had a significant association with increased hyperlipidemia risk in adults. However, long sleep duration was decidedly associated with low HDL-C (RR:0.19, 95%CI: - 0.03-0.40, P < 0.05) and high triglycerides (RR: - 0.20, 95%CI: - 0.43-0.03, P < 0.05) in children and adolescents. CONCLUSION: Long sleep duration has strong associations with risks of low HDL-C and high triglycerides in children and adolescents. The mechanisms underlying this association deserves to be explored in future studies.
Authors: Neil J Stone; Jennifer G Robinson; Alice H Lichtenstein; C Noel Bairey Merz; Conrad B Blum; Robert H Eckel; Anne C Goldberg; David Gordon; Daniel Levy; Donald M Lloyd-Jones; Patrick McBride; J Sanford Schwartz; Susan T Shero; Sidney C Smith; Karol Watson; Peter W F Wilson Journal: J Am Coll Cardiol Date: 2013-11-12 Impact factor: 24.094
Authors: Valery L Feigin; Gregory A Roth; Mohsen Naghavi; Priya Parmar; Rita Krishnamurthi; Sumeet Chugh; George A Mensah; Bo Norrving; Ivy Shiue; Marie Ng; Kara Estep; Kelly Cercy; Christopher J L Murray; Mohammad H Forouzanfar Journal: Lancet Neurol Date: 2016-06-09 Impact factor: 44.182