Literature DB >> 34617176

Analysis of Morphological Changes in the CNS and Internal Organs of Macaca mulatta Monkeys after Intracerebral Injection of a Low-Attenuated Rubella Virus Strain.

O A Shamsutdinova1, D V Bulgin2, D D Karal-Ogly2, I N Lavrent'eva3.   

Abstract

We studied the localization and severity of morphological changes in CNS and internal organs of animals intacerebrally infected with a low-attenuated rubella virus strain "Orlov-14". The data obtained can be used as morphological criteria reflecting low level of attenuation of rubella virus strains to improve the control of the safety of attenuated strains of live rubella vaccines.
© 2021. Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Macaca mulatta monkeys; attenuation; intracerebral inoculation; rubella virus

Mesh：

Substances：

Year:  2021        PMID： 34617176     DOI： 10.1007/s10517-021-05291-4

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  5 in total

1.  [The multiplex method of estimation of humoral immunity to vaccine regulated childhood infections].

Authors:  A V Ersh; A G Poltavchenko; S A Pyankov; A P Agaphonov; N A Krivenchuk; D V Butorin
Journal:  Vopr Virusol       Date:  2015

2.  Reactogenicity and immunogenicity of a live attenuated tetravalent measles-mumps-rubella-varicella (MMRV) vaccine.

Authors:  Terry Nolan; Peter McIntyre; Don Roberton; Dominique Descamps
Journal:  Vaccine       Date:  2002-12-13       Impact factor: 3.641

Review 3.  Safety of live vaccinations on immunosuppressive therapy in patients with immune-mediated inflammatory diseases, solid organ transplantation or after bone-marrow transplantation - A systematic review of randomized trials, observational studies and case reports.

Authors:  Evelina Croce; Christoph Hatz; Emile F Jonker; L G Visser; Veronika K Jaeger; Silja Bühler
Journal:  Vaccine       Date:  2017-02-03       Impact factor: 3.641

4.  Immunogenicity and reactogenicity of tetravalent vaccine for measles, mumps, rubella and varicella (MMRV) in healthy children: a meta-analysis of randomized controlled trials.

Authors:  Julia Hy Leung; Hoyee W Hirai; Kelvin Kf Tsoi
Journal:  Expert Rev Vaccines       Date:  2015-06-16       Impact factor: 5.217

5.  Strengthening routine immunization through measles-rubella elimination.

Authors:  Robin J Biellik; Walter A Orenstein
Journal:  Vaccine       Date:  2018-07-21       Impact factor: 3.641
  5 in total

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