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Literature DB >> 34616083

A step towards therapeutics for dengue.

Scott B Biering, Eva Harris.

Abstract

Entities: Chemical

Keywords: Drug discovery; Infection; Virology

Mesh：

Year: 2021 PMID： 34616083 DOI： 10.1038/d41586-021-02638-9

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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10 in total

Review 1. Targeting dengue virus NS4B protein for drug discovery.

Authors: Xuping Xie; Jing Zou; Qing-Yin Wang; Pei-Yong Shi
Journal: Antiviral Res Date: 2015-03-19 Impact factor: 5.970

2. Inhibition of dengue virus by targeting viral NS4B protein.

Authors: Xuping Xie; Qing-Yin Wang; Hao Ying Xu; Min Qing; Laura Kramer; Zhiming Yuan; Pei-Yong Shi
Journal: J Virol Date: 2011-08-24 Impact factor: 5.103

3. Characterization of a dengue NS4B inhibitor originating from an HCV small molecule library.

Authors: Ilane Hernandez-Morales; Peggy Geluykens; Marleen Clynhens; Rudy Strijbos; Olivia Goethals; Sarah Megens; Nick Verheyen; Stefaan Last; David McGowan; Erwin Coesemans; Benoît De Boeck; Bart Stoops; Benoit Devogelaere; Frederik Pauwels; Koen Vandyck; Jan Martin Berke; Pierre Raboisson; Kenneth Simmen; Pedro Lory; Marnix Van Loock
Journal: Antiviral Res Date: 2017-10-14 Impact factor: 5.970

4. NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models.

Authors: Stephanie A Moquin; Oliver Simon; Ratna Karuna; Suresh B Lakshminarayana; Fumiaki Yokokawa; Feng Wang; Chandra Saravanan; Jin Zhang; Craig W Day; Katherine Chan; Qing-Yin Wang; Siyan Lu; Hongping Dong; Kah Fei Wan; Siew Pheng Lim; Wei Liu; Cheah Chen Seh; Yen-Liang Chen; Haoying Xu; David T Barkan; Cyrille S Kounde; Wei Lin Sandra Sim; Gang Wang; Hui-Quan Yeo; Bin Zou; Wai Ling Chan; Mei Ding; Jae-Geun Song; Min Li; Colin Osborne; Francesca Blasco; Christopher Sarko; David Beer; Ghislain M C Bonamy; Vito G Sasseville; Pei-Yong Shi; Thierry T Diagana; Bryan K S Yeung; Feng Gu
Journal: Sci Transl Med Date: 2021-02-03 Impact factor: 17.956

5. Discovery of Dengue Virus NS4B Inhibitors.

Authors: Qing-Yin Wang; Hongping Dong; Bin Zou; Ratna Karuna; Kah Fei Wan; Jing Zou; Agatha Susila; Andy Yip; Chao Shan; Kim Long Yeo; Haoying Xu; Mei Ding; Wai Ling Chan; Feng Gu; Peck Gee Seah; Wei Liu; Suresh B Lakshminarayana; CongBao Kang; Julien Lescar; Francesca Blasco; Paul W Smith; Pei-Yong Shi
Journal: J Virol Date: 2015-08 Impact factor: 5.103

6. Discovery of Indole Derivatives as Novel and Potent Dengue Virus Inhibitors.

Authors: Dorothée Bardiot; Mohamed Koukni; Wim Smets; Gunter Carlens; Michael McNaughton; Suzanne Kaptein; Kai Dallmeier; Patrick Chaltin; Johan Neyts; Arnaud Marchand
Journal: J Med Chem Date: 2018-09-12 Impact factor: 7.446

7. A randomized, double-blind placebo controlled trial of balapiravir, a polymerase inhibitor, in adult dengue patients.

Authors: Nguyet Minh Nguyen; Chau Nguyen Bich Tran; Lam Khanh Phung; Kien Thi Hue Duong; Huy le Anh Huynh; Jeremy Farrar; Quyen Than Ha Nguyen; Hien Tinh Tran; Chau Van Vinh Nguyen; Laura Merson; Long Truong Hoang; Martin L Hibberd; Pauline P K Aw; Andreas Wilm; Niranjan Nagarajan; Dung Thi Nguyen; Mai Phuong Pham; Truong Thanh Nguyen; Hassan Javanbakht; Klaus Klumpp; Janet Hammond; Rosemary Petric; Marcel Wolbers; Chinh Tran Nguyen; Cameron P Simmons
Journal: J Infect Dis Date: 2012-07-17 Impact factor: 5.226

2 in total

Review 1. Structures and Dynamics of Dengue Virus Nonstructural Membrane Proteins.

Authors: Qingxin Li; Congbao Kang
Journal: Membranes (Basel) Date: 2022-02-17

Review 2. Dengue virus NS4B protein as a target for developing antivirals.

Authors: Qingxin Li; Congbao Kang
Journal: Front Cell Infect Microbiol Date: 2022-08-09 Impact factor: 6.073