Literature DB >> 34610644

Natural Language Mapping of Electrocardiogram Interpretations to a Standardized Ontology.

Richard H Epstein1, Yuel-Kai Jean1, Roman Dudaryk1, Robert E Freundlich2, Jeremy P Walco2, Dorothee A Mueller2, Shawn E Banks1.   

Abstract

BACKGROUND: Interpretations of the electrocardiogram (ECG) are often prepared using software outside the electronic health record (EHR) and imported via an interface as a narrative note. Thus, natural language processing is required to create a computable representation of the findings. Challenges include misspellings, nonstandard abbreviations, jargon, and equivocation in diagnostic interpretations.
OBJECTIVES: Our objective was to develop an algorithm to reliably and efficiently extract such information and map it to the standardized ECG ontology developed jointly by the American Heart Association, the American College of Cardiology Foundation, and the Heart Rhythm Society. The algorithm was to be designed to be easily modifiable for use with EHRs and ECG reporting systems other than the ones studied.
METHODS: An algorithm using natural language processing techniques was developed in structured query language to extract and map quantitative and diagnostic information from ECG narrative reports to the cardiology societies' standardized ECG ontology. The algorithm was developed using a training dataset of 43,861 ECG reports and applied to a test dataset of 46,873 reports.
RESULTS: Accuracy, precision, recall, and the F1-measure were all 100% in the test dataset for the extraction of quantitative data (e.g., PR and QTc interval, atrial and ventricular heart rate). Performances for matches in each diagnostic category in the standardized ECG ontology were all above 99% in the test dataset. The processing speed was approximately 20,000 reports per minute. We externally validated the algorithm from another institution that used a different ECG reporting system and found similar performance.
CONCLUSION: The developed algorithm had high performance for creating a computable representation of ECG interpretations. Software and lookup tables are provided that can easily be modified for local customization and for use with other EHR and ECG reporting systems. This algorithm has utility for research and in clinical decision-support where incorporation of ECG findings is desired. Thieme. All rights reserved.

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Year:  2021        PMID: 34610644      PMCID: PMC8595771          DOI: 10.1055/s-0041-1736312

Source DB:  PubMed          Journal:  Methods Inf Med        ISSN: 0026-1270            Impact factor:   1.800


  9 in total

1.  Identifying UMLS concepts from ECG Impressions using KnowledgeMap.

Authors:  Joshua C Denny; Anderson Spickard; Randolph A Miller; Jonathan Schildcrout; Dawood Darbar; S Trent Rosenbloom; Josh F Peterson
Journal:  AMIA Annu Symp Proc       Date:  2005

Review 2.  Recommendations for the standardization and interpretation of the electrocardiogram: part II: electrocardiography diagnostic statement list a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society Endorsed by the International Society for Computerized Electrocardiology.

Authors:  Jay W Mason; E William Hancock; Leonard S Gettes; James J Bailey; Rory Childers; Barbara J Deal; Mark Josephson; Paul Kligfield; Jan A Kors; Peter Macfarlane; Olle Pahlm; David M Mirvis; Peter Okin; Pentti Rautaharju; Borys Surawicz; Gerard van Herpen; Galen S Wagner; Hein Wellens
Journal:  J Am Coll Cardiol       Date:  2007-03-13       Impact factor: 24.094

3.  Identifying QT prolongation from ECG impressions using a general-purpose Natural Language Processor.

Authors:  Joshua C Denny; Randolph A Miller; Lemuel Russell Waitman; Mark A Arrieta; Joshua F Peterson
Journal:  Int J Med Inform       Date:  2008-10-19       Impact factor: 4.046

Review 4.  The Computerized ECG: Friend and Foe.

Authors:  Harold Smulyan
Journal:  Am J Med       Date:  2018-09-08       Impact factor: 4.965

Review 5.  Establishing reference ranges for ambulatory electrocardiography parameters: meta-analysis.

Authors:  Curtis B Williams; Jason G Andrade; Nathaniel M Hawkins; Christopher Cheung; Andrew Krahn; Zachary W Laksman; Matthew T Bennett; Brett Heilbron; Shanta Chakrabarti; John A Yeung-Lai-Wah; Marc W Deyell
Journal:  Heart       Date:  2020-07-20       Impact factor: 5.994

Review 6.  The electronic health record for translational research.

Authors:  Luke V Rasmussen
Journal:  J Cardiovasc Transl Res       Date:  2014-07-29       Impact factor: 4.132

7.  Unlocking echocardiogram measurements for heart disease research through natural language processing.

Authors:  Olga V Patterson; Matthew S Freiberg; Melissa Skanderson; Samah J Fodeh; Cynthia A Brandt; Scott L DuVall
Journal:  BMC Cardiovasc Disord       Date:  2017-06-12       Impact factor: 2.298

8.  A Natural Language Processing Tool for Large-Scale Data Extraction from Echocardiography Reports.

Authors:  Chinmoy Nath; Mazen S Albaghdadi; Siddhartha R Jonnalagadda
Journal:  PLoS One       Date:  2016-04-28       Impact factor: 3.240

Review 9.  The Unified Medical Language System at 30 Years and How It Is Used and Published: Systematic Review and Content Analysis.

Authors:  Xia Jing
Journal:  JMIR Med Inform       Date:  2021-08-27
  9 in total

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