| Literature DB >> 34596858 |
Katherine Rhea1,2.
Abstract
Bio-Layer Interferometry (BLI) enables the detection and characterization of molecular interactions in real-time without the hassle and interference of labeling. The affinity constant (KD) obtained in the BLI analysis is an excellent indicator of quality of biomolecules such as antibodies, aptamers, peptides, etc. This method was used to analyze a peptide macrocycle against the Abrax protein, but can be used for any peptide macrocycle/analyte system.Entities:
Keywords: Affinity; Analyte; Bio-layer Interferometry; Kinetics; Label-Free Detection; Ligand; Peptides
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Year: 2022 PMID： 34596858 DOI： 10.1007/978-1-0716-1689-5_19
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745