Literature DB >> 34594073

Copper-impregnated socks: A novel therapeutic option for combating occupational dermatophytosis.

Sukriti Baveja1, Chetan C Patil2, Surbhi Vashisht3, Deepak Vashisht4, Vikas Pathania5, Durga Tripathy6, Bhavni Oberoi7.   

Abstract

BACKGROUND: Operational and training requirements of soldiers necessitate prolonged use of occlusive footwear which makes them susceptible to Tinea pedis and affects their performance. This study assesses copper oxide-impregnated socks as a treatment modality in soldiers with Tinea pedis.
METHODS: Three hundred serving soldiers with Tinea pedis were randomly divided in two groups of 150 cases each. One group was supplied with 02 pairs of polyester copper oxide-impregnated socks and the second group was treated with oral terbinafine 250mg /day for two weeks and topical terbinafine twice a day for three weeks. Five end points viz. scaling, erythema, fissuring, vesicular eruptions and itching were monitored using the visual analogue score (VAS) weekly for 03 weeks.
RESULTS: Copper oxide socks helped in reducing all the end points as assessed by VAS. The group treated with terbinafine showed better response; however test socks were as efficacious as oral and topical terbinafine in controlling fissuring and vesiculation. Safety profile of the copper impregnated socks was comparable with the conventional treatment.
CONCLUSION: Copper-impregnated socks are effective and safe in treating Tinea pedis. They may also have prophylactic role in tinea pedis in susceptible serving soldiers deployed at remote locations in different terrain and weather conditions.
© 2021 Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd.

Entities:  

Keywords:  Copper oxide; Socks; Soldiers; Tinea pedis

Year:  2021        PMID: 34594073      PMCID: PMC8459065          DOI: 10.1016/j.mjafi.2021.01.010

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


  11 in total

1.  Copper-induced vascular endothelial growth factor expression and wound healing.

Authors:  Chandan K Sen; Savita Khanna; Mika Venojarvi; Prashant Trikha; E Christopher Ellison; Thomas K Hunt; Sashwati Roy
Journal:  Am J Physiol Heart Circ Physiol       Date:  2002-05       Impact factor: 4.733

2.  Molecular mechanisms of enhanced wound healing by copper oxide-impregnated dressings.

Authors:  Gadi Borkow; Jeffrey Gabbay; Rima Dardik; Arthur I Eidelman; Yossi Lavie; Yona Grunfeld; Sergey Ikher; Monica Huszar; Richard C Zatcoff; Moshe Marikovsky
Journal:  Wound Repair Regen       Date:  2010-03-12       Impact factor: 3.617

3.  Indian Association of Dermatologists, Venereologists and Leprologists (IADVL) Task Force against Recalcitrant Tinea (ITART) Consensus on the Management of Glabrous Tinea (INTACT).

Authors:  Madhu Rengasamy; Manjunath M Shenoy; Sunil Dogra; Neelakandhan Asokan; Ananta Khurana; Shital Poojary; Jyothi Jayaraman; Ameet R Valia; Kabir Sardana; Seetharam Kolalapudi; Yogesh Marfatia; P Narasimha Rao; Ramesh M Bhat; Mahendra Kura; Deepika Pandhi; Shyamanta Barua; Vibhor Kaushal
Journal:  Indian Dermatol Online J       Date:  2020-07-13

Review 4.  Copper as a biocidal tool.

Authors:  Gadi Borkow; Jeffrey Gabbay
Journal:  Curr Med Chem       Date:  2005       Impact factor: 4.530

Review 5.  Copper hypersensitivity: dermatologic aspects--an overview.

Authors:  Jurij J Hostynek; Howard I Maibach
Journal:  Rev Environ Health       Date:  2003 Jul-Sep       Impact factor: 3.458

Review 6.  The human tri-peptide GHK and tissue remodeling.

Authors:  Loren Pickart
Journal:  J Biomater Sci Polym Ed       Date:  2008       Impact factor: 3.517

Review 7.  Adherence to topical dermatological therapy: lessons from oral drug treatment.

Authors:  G Gupta; P Mallefet; D W Kress; A Sergeant
Journal:  Br J Dermatol       Date:  2009-04-22       Impact factor: 9.302

8.  Combination treatment of oral terbinafine with topical terbinafine and 10% urea ointment in hyperkeratotic type tinea pedis.

Authors:  Tian-Wei Shi; Jiang-An Zhang; Xian-Wei Zhang; Hong-Xing Yu; Yong-Bo Tang; Jian-Bin Yu
Journal:  Mycoses       Date:  2014-04-03       Impact factor: 4.377

9.  Beneficial regulation of matrix metalloproteinases for skin health.

Authors:  Neena Philips; Susan Auler; Raul Hugo; Salvador Gonzalez
Journal:  Enzyme Res       Date:  2011-03-08

10.  Expert Consensus on The Management of Dermatophytosis in India (ECTODERM India).

Authors:  Murlidhar Rajagopalan; Arun Inamadar; Asit Mittal; Autar K Miskeen; C R Srinivas; Kabir Sardana; Kiran Godse; Krina Patel; Madhu Rengasamy; Shivaprakash Rudramurthy; Sunil Dogra
Journal:  BMC Dermatol       Date:  2018-07-24
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