Literature DB >> 3459154

Complete amino acid sequence of chicken cartilage link protein deduced from cDNA clones.

F Deák, I Kiss, K J Sparks, W S Argraves, G Hampikian, P F Goetinck.   

Abstract

cDNA clones coding for chicken cartilage link protein were isolated and sequenced. The DNA sequence for the entire core polypeptide of the mature link protein and the predicted signal peptide consists of 1065 nucleotides. The deduced primary translation product (355 amino acids) has a molecular mass of 40.7 kDa; the calculated molecular mass of the mature link protein core polypeptide (340 amino acids) is 39.06 kDa. The DNA sequence contains two tandemly arranged repeat sequences that may code for repeated functional domains of link protein involved in binding to hyaluronic acid. The mRNAs for chicken link protein are 6.0, 5.8, and 3.0 kilobase pairs, and the difference between the sizes of the RNA species lies in the 3' untranslated region.

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Year:  1986        PMID： 3459154      PMCID： PMC323604          DOI： 10.1073/pnas.83.11.3766

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  32 in total

1.  The link protein in proteoglycan aggregates from the Swarm rat chondrosarcoma.

Authors:  T R Oegema; M Brown; D D Dziewiatkowski
Journal:  J Biol Chem       Date:  1977-09-25       Impact factor: 5.157

2.  RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination.

Authors:  H Lehrach; D Diamond; J M Wozney; H Boedtker
Journal:  Biochemistry       Date:  1977-10-18       Impact factor: 3.162

3.  Aggregation of cartilage proteoglycans. I. The role of hyaluronic acid.

Authors:  V C Hascall; D Heinegård
Journal:  J Biol Chem       Date:  1974-07-10       Impact factor: 5.157

4.  Aggregation of cartilage proteoglycans. 3. Characteristics of the proteins isolated from trypsin digests of aggregates.

Authors:  D Heinegård; V C Hascall
Journal:  J Biol Chem       Date:  1974-07-10       Impact factor: 5.157

5.  Identical precursors for serum transferrin and egg white conalbumin.

Authors:  S N Thibodeau; D C Lee; R D Palmiter
Journal:  J Biol Chem       Date:  1978-06-10       Impact factor: 5.157

6.  The interaction of link proteins with proteoglycan monomers in the absence of hyaluronic acid.

Authors:  B Caterson; J Baker
Journal:  Biochem Biophys Res Commun       Date:  1978-02-14       Impact factor: 3.575

7.  The role of link-protein in the structure of cartilage proteoglycan aggregates.

Authors:  T E Hardingham
Journal:  Biochem J       Date:  1979-01-01       Impact factor: 3.857

8.  Isolation and characterization of proteoglycans from the swarm rat chondrosarcoma.

Authors:  T R Oegema; V C Hascall; D D Dziewiatkowski
Journal:  J Biol Chem       Date:  1975-08-10       Impact factor: 5.157

9.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

10.  Nucleotide sequence of the rightward operator of phage lambda.

Authors:  T Maniatis; A Jeffrey; D G Kleid
Journal:  Proc Natl Acad Sci U S A       Date:  1975-03       Impact factor: 11.205
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  20 in total

1.  Growth as a solid tumor or reduced glucose concentrations in culture reversibly induce CD44-mediated hyaluronan recognition by Chinese hamster ovary cells.

Authors:  Z Zheng; R D Cummings; P E Pummill; P W Kincade
Journal:  J Clin Invest       Date:  1997-09-01       Impact factor: 14.808

2.  Molecular cloning of chicken aggrecan. Structural analyses.

Authors:  L Chandrasekaran; M L Tanzer
Journal:  Biochem J       Date:  1992-12-15       Impact factor: 3.857

3.  Complex pattern of alternative splicing generates unusual diversity in the leader sequence of the chicken link protein mRNA.

Authors:  F Deák; E Barta; S Mestric; M Biesold; I Kiss
Journal:  Nucleic Acids Res       Date:  1991-09-25       Impact factor: 16.971

4.  Cartilage proteoglycan aggregate is degraded more extensively by cathepsin L than by cathepsin B.

Authors:  Q Nguyen; J S Mort; P J Roughley
Journal:  Biochem J       Date:  1990-03-01       Impact factor: 3.857

5.  Degradation of proteoglycan aggregate by a cartilage metalloproteinase. Evidence for the involvement of stromelysin in the generation of link protein heterogeneity in situ.

Authors:  Q Nguyen; G Murphy; P J Roughley; J S Mort
Journal:  Biochem J       Date:  1989-04-01       Impact factor: 3.857

6.  Structure of the chicken link protein gene: exons correlate with the protein domains.

Authors:  I Kiss; F Deák; S Mestrić; H Delius; J Soos; K Dékány; W S Argraves; K J Sparks; P F Goetinck
Journal:  Proc Natl Acad Sci U S A       Date:  1987-09       Impact factor: 11.205

7.  Evolution of the hyaluronan-binding module of link protein.

Authors:  E Barta; F Deák; I Kiss
Journal:  Biochem J       Date:  1993-06-15       Impact factor: 3.857

8.  Structural features of cartilage matrix protein deduced from cDNA.

Authors:  W S Argraves; F Deák; K J Sparks; I Kiss; P F Goetinck
Journal:  Proc Natl Acad Sci U S A       Date:  1987-01       Impact factor: 11.205

9.  Human link protein gene: structure and transcription pattern in chondrocytes.

Authors:  J Dudhia; M T Bayliss; T E Hardingham
Journal:  Biochem J       Date:  1994-10-01       Impact factor: 3.857

10.  A study of the interaction between cartilage proteoglycan and link protein.

Authors:  D J Thornton; J K Sheehan; I A Nieduszynski
Journal:  Biochem J       Date:  1987-12-15       Impact factor: 3.857
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