Literature DB >> 3458209

Pluripoietin alpha: a second human hematopoietic colony-stimulating factor produced by the human bladder carcinoma cell line 5637.

J L Gabrilove, K Welte, P Harris, E Platzer, L Lu, E Levi, R Mertelsmann, M A Moore.   

Abstract

We have identified a factor constitutively produced by the human bladder carcinoma cell line 5637, which has the following capacities: to induce the differentiation of the human promyelocytic leukemic cell line HL-60; to induce the expression of chemotactic peptide receptors in leukemic cells as well as in normal peripheral blood granulocytes; to function as a chemoattractant for neutrophils as well as, under certain conditions, inhibiting their migration; to support the growth of eosinophil and granulocyte/macrophage progenitors, which is maximal when scored at day 14; and to support the growth of human mixed pluripotent progenitors and erythroid bursts from normal human bone marrow. This factor has a molecular size of 32 kDa by gel filtration and 16.5 kDa by NaDodSO4/PAGE. We have termed this factor pluripoietin alpha.

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Year:  1986        PMID: 3458209      PMCID: PMC323321          DOI: 10.1073/pnas.83.8.2478

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  17 in total

1.  Isolation of lymphocytes, granulocytes and macrophages.

Authors:  A Bøyum
Journal:  Scand J Immunol       Date:  1976-06       Impact factor: 3.487

2.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

3.  A cell line secreting stimulating factors for CFU-GEMM culture.

Authors:  C D Myers; F E Katz; G Joshi; J L Millar
Journal:  Blood       Date:  1984-07       Impact factor: 22.113

4.  Chemotaxis of monocytes and neutrophils to platelet-derived growth factor.

Authors:  T F Deuel; R M Senior; J S Huang; G L Griffin
Journal:  J Clin Invest       Date:  1982-04       Impact factor: 14.808

5.  Purified human granulocyte-macrophage colony-stimulating factor: direct action on neutrophils.

Authors:  J C Gasson; R H Weisbart; S E Kaufman; S C Clark; R M Hewick; G G Wong; D W Golde
Journal:  Science       Date:  1984-12-14       Impact factor: 47.728

6.  Synergism between hemopoietic growth factors (HGFs) detected by their effects on cells bearing receptors for a lineage specific HGF: assay of hemopoietin-1.

Authors:  S H Bartelmez; E R Stanley
Journal:  J Cell Physiol       Date:  1985-03       Impact factor: 6.384

7.  Separation of functionally distinct human granulocyte-macrophage colony-stimulating factors.

Authors:  N A Nicola; D Metcalf; G R Johnson; A W Burgess
Journal:  Blood       Date:  1979-09       Impact factor: 22.113

8.  Clonal analysis of the response of HL60 human myeloid leukemia cells to biological regulators.

Authors:  D Metcalf
Journal:  Leuk Res       Date:  1983       Impact factor: 3.156

9.  Purification and biochemical characterization of human pluripotent hematopoietic colony-stimulating factor.

Authors:  K Welte; E Platzer; L Lu; J L Gabrilove; E Levi; R Mertelsmann; M A Moore
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205

10.  Clonal extinction of myelomonocytic leukemic cells by serum from mice injected with endotoxin.

Authors:  D Metcalf
Journal:  Int J Cancer       Date:  1980-02-15       Impact factor: 7.396

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  17 in total

1.  Hematopoietic growth factors.

Authors:  C A Sieff
Journal:  J Clin Invest       Date:  1987-06       Impact factor: 14.808

Review 2.  Colony-stimulating factors in the pathogenesis and treatment of disease.

Authors:  D J Williamson; C G Begley
Journal:  Postgrad Med J       Date:  1987-12       Impact factor: 2.401

3.  Interleukin 1 stimulates fibroblasts to synthesize granulocyte-macrophage and granulocyte colony-stimulating factors. Mechanism for the hematopoietic response to inflammation.

Authors:  K Kaushansky; N Lin; J W Adamson
Journal:  J Clin Invest       Date:  1988-01       Impact factor: 14.808

Review 4.  Human granulocyte colony stimulating factor.

Authors:  E Platzer; J R Kalden
Journal:  Blut       Date:  1987-03

5.  Stimulation of oxidative metabolism of granulocytes by recombinant granulocyte-macrophage-colony-stimulating-factor and a conditioned medium of a urinary bladder carcinoma cell line.

Authors:  M Klausmann; K H Pflüger; D Krumwieh; F R Seiler; K Havemann
Journal:  Blut       Date:  1987-05

6.  Low concentrations of cytosine arabinoside, 6-thioguanine, actinomycin-D and aclacinomycin A stimulates the differentiation of normal human marrow myeloid progenitor cells.

Authors:  H T Hassan; J K Rees
Journal:  Med Oncol Tumor Pharmacother       Date:  1989

7.  Human granulocyte-macrophage colony-stimulating factor is a growth factor active on a variety of cell types of nonhemopoietic origin.

Authors:  S Dedhar; L Gaboury; P Galloway; C Eaves
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

8.  Comparative effects in vivo of recombinant murine interleukin 3, natural murine colony-stimulating factor-1, and recombinant murine granulocyte-macrophage colony-stimulating factor on myelopoiesis in mice.

Authors:  H E Broxmeyer; D E Williams; S Cooper; R K Shadduck; S Gillis; A Waheed; D L Urdal; D C Bicknell
Journal:  J Clin Invest       Date:  1987-03       Impact factor: 14.808

9.  Interleukin 1 regulates hematopoietic activity, a role previously ascribed to hemopoietin 1.

Authors:  D Y Mochizuki; J R Eisenman; P J Conlon; A D Larsen; R J Tushinski
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

10.  Synergy of interleukin 1 and granulocyte colony-stimulating factor: in vivo stimulation of stem-cell recovery and hematopoietic regeneration following 5-fluorouracil treatment of mice.

Authors:  M A Moore; D J Warren
Journal:  Proc Natl Acad Sci U S A       Date:  1987-10       Impact factor: 11.205

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