Literature DB >> 3457016

Transforming growth factor type beta regulation of actin mRNA.

E B Leof, J A Proper, M J Getz, H L Moses.   

Abstract

Stimulation of quiescent cultures of AKR-2B cells with transforming growth factor type beta (TGF beta) resulted in a transitory increase in actin cytoplasmic poly(A) + RNA. Levels of actin mRNA peaked approximately 4-8 hours subsequent to TGF beta addition and approached basal levels by 24 hours. The accumulation of actin transcripts was dose dependent and insensitive to inhibitors of protein synthesis; 1-3 ng/ml TGF beta induced maximal actin gene expression. Actin isotype-specific probes demonstrated that both beta- and gamma-cytoplasmic actins are induced by TGF beta.

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Year:  1986        PMID： 3457016     DOI： 10.1002/jcp.1041270111

Source DB:  PubMed          Journal:  J Cell Physiol        ISSN： 0021-9541            Impact factor:   6.384


  25 in total

1.  Modulation of actin mRNAs in cultured vascular cells by matrix components and TGF-beta 1.

Authors:  O Kocher; J A Madri
Journal:  In Vitro Cell Dev Biol       Date:  1989-05

2.  Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta.

Authors:  R J Coffey; C C Bascom; N J Sipes; R Graves-Deal; B E Weissman; H L Moses
Journal:  Mol Cell Biol       Date:  1988-08       Impact factor: 4.272

3.  Modulation of transforming growth factor type beta action by activated ras and c-myc.

Authors:  E B Leof; J A Proper; H L Moses
Journal:  Mol Cell Biol       Date:  1987-07       Impact factor: 4.272

4.  Cell-type specificity of β-actin expression and its clinicopathological correlation in gastric adenocarcinoma.

Authors:  Shafqat A Khan; Monica Tyagi; Ajit K Sharma; Savio G Barreto; Bhawna Sirohi; Mukta Ramadwar; Shailesh V Shrikhande; Sanjay Gupta
Journal:  World J Gastroenterol       Date:  2014-09-14       Impact factor: 5.742

5.  Bone morphogenetic proteins regulate osteoprotegerin and its ligands in human vascular smooth muscle cells.

Authors:  Kirsten Q T Nguyen; Ping Olesen; Thomas Ledet; Lars Melholt Rasmussen
Journal:  Endocrine       Date:  2007-09-29       Impact factor: 3.633

6.  Regulation of adhesion and growth of fibrosarcoma cells by NF-kappa B RelA involves transforming growth factor beta.

Authors:  J R Perez; K A Higgins-Sochaski; J Y Maltese; R Narayanan
Journal:  Mol Cell Biol       Date:  1994-08       Impact factor: 4.272

7.  beta-Actin and GAPDH housekeeping gene expression in asthmatic airways is variable and not suitable for normalising mRNA levels.

Authors:  E M Glare; M Divjak; M J Bailey; E H Walters
Journal:  Thorax       Date:  2002-09       Impact factor: 9.139

8.  Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts.

Authors:  R Raghow; A E Postlethwaite; J Keski-Oja; H L Moses; A H Kang
Journal:  J Clin Invest       Date:  1987-04       Impact factor: 14.808

9.  Transforming growth factor beta 1, a potent chemoattractant for human neutrophils, bypasses classic signal-transduction pathways.

Authors:  J Reibman; S Meixler; T C Lee; L I Gold; B N Cronstein; K A Haines; S L Kolasinski; G Weissmann
Journal:  Proc Natl Acad Sci U S A       Date:  1991-08-01       Impact factor: 11.205

10.  Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing.

Authors:  R Montesano; L Orci
Journal:  Proc Natl Acad Sci U S A       Date:  1988-07       Impact factor: 11.205
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