Literature DB >> 3455975

Production and characterization of monoclonal antibodies to Bacteroides gingivalis.

L G Simonson, B R Merrell, R F Rouse, I L Shklair.   

Abstract

The rapid detection of Bacteroides gingivalis by immunological methods using monoclonal antibodies could greatly improve the diagnosis and prognosis of severe periodontal disease in adults. In this study, three distinct hybridomas were produced which secrete monoclonal antibodies to soluble and whole-cell antigen preparations of B. gingivalis. The BGII, V F9/2D hybridoma produced a murine antibody that can detect all of the B. gingivalis isolates studied while never cross-reacting with the other oral microbial antigens tested.

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Year:  1986        PMID： 3455975     DOI： 10.1177/00220345860650021801

Source DB:  PubMed          Journal:  J Dent Res        ISSN： 0022-0345            Impact factor:   6.116


  7 in total

1.  Monoclonal antibodies that recognize a specific surface antigen of Treponema denticola.

Authors:  L G Simonson; R F Rouse; S W Bockowski
Journal:  Infect Immun       Date:  1988-01       Impact factor: 3.441

Review 2.  Biology of asaccharolytic black-pigmented Bacteroides species.

Authors:  D Mayrand; S C Holt
Journal:  Microbiol Rev       Date:  1988-03

3.  Quantitative relationship of Treponema denticola to severity of periodontal disease.

Authors:  L G Simonson; C H Goodman; J J Bial; H E Morton
Journal:  Infect Immun       Date:  1988-04       Impact factor: 3.441

4.  Identification of Streptococcus sobrinus with monoclonal antibodies.

Authors:  J J de Soet; P J van Dalen; B J Appelmelk; J de Graaff
Journal:  J Clin Microbiol       Date:  1987-12       Impact factor: 5.948

5.  Fluorescence immunoassay for detecting periodontal bacterial pathogens in plaque.

Authors:  L F Wolff; L Anderson; G P Sandberg; D M Aeppli; C E Shelburne
Journal:  J Clin Microbiol       Date:  1991-08       Impact factor: 5.948

6.  Pathogen-related spirochetes identified within gingival tissue from patients with acute necrotizing ulcerative gingivitis.

Authors:  G R Riviere; K S Weisz; L G Simonson; S A Lukehart
Journal:  Infect Immun       Date:  1991-08       Impact factor: 3.441

7.  Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis.

Authors:  Marianne Engström; Kaja Eriksson; Linkiat Lee; Monika Hermansson; Anders Johansson; Anthony P Nicholas; Natalija Gerasimcik; Karin Lundberg; Lars Klareskog; Anca Irinel Catrina; Tülay Yucel-Lindberg
Journal:  J Transl Med       Date:  2018-07-31       Impact factor: 5.531
  7 in total

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