Dal Lae Ju1, Sun Wook Cho2, Chae Won Chung2, Young Ah Lee3, Gi Jeong Cheon4, Young Joo Park2,5, Choong Ho Shin3, Jong Kwan Jun6, June-Key Chung4, Sue K Park7,8,9, YoonJu Song10. 1. Department of Nutrition, SMG-SNU Boramae Medical Center, Seoul, 07061, Korea. 2. Department of Internal Medicine, Seoul National University College of Medicine and Seoul National University Hospital, Seoul, 03080, Korea. 3. Department of Pediatrics, Seoul National University College of Medicine, Seoul, 03080, Korea. 4. Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, 03080, Korea. 5. Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Sicence and Technology, Seoul National University, Seoul, Korea. 6. Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, 03080, Korea. 7. Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, 03080, Korea. suepark@snu.ac.kr. 8. Cancer Research Institute, Seoul National University, Seoul, 03080, Korea. suepark@snu.ac.kr. 9. Integrated Major in Innovative Medical Science, Seoul National University College of Medicine, Seoul, Korea. suepark@snu.ac.kr. 10. Department of Food Science and Nutrition, Catholic University of Korea, 43 Jibong-ro Wonmi-gu, Bucheon-si, 14662, Republic of Korea. yjsong@catholic.ac.kr.
Abstract
PURPOSE: Given the high consumption of seaweed soup by pregnant and lactating Korean women, concerns have been raised about excessive iodine intake. We evaluated the effects of maternal iodine intake on maternal thyroid function and birth outcomes. We also evaluated iodine intake via seaweed soup during late pregnancy and the early postpartum period. METHODS: A total of 349 pregnant women of the Ideal Breast Milk cohort were recruited in late pregnancy, of whom 302 revisited after delivery. Three-day dietary records were assessed at each visit. Blood was collected for thyroid function test. Obstetrical and birth outcomes were obtained. RESULTS: The median dietary iodine intake was 459 μg/day (interquartile range [IQR] 326.5-647.4 μg/day) during pregnancy. Dietary iodine intake by quartile was not significantly associated with maternal thyroid status, or obstetrical or neonatal outcomes. However, the dietary iodine intake in the early postpartum period was 1759 μg/day (IQR 1026.7-2491.1 μg/day) because of a marked increase in seaweed soup consumption. Of all women, 25.8% consumed seaweed soup more than once over the 3 days of dietary records when pregnant, but the figure rose to 93.4% postpartum. Of postpartum women who consumed seaweed soup daily, the median dietary iodine intakes were 1355, 2394, and 3063 μg/day (soup at one, two, and three-or-four meals). CONCLUSIONS: In these iodine-replete pregnant women, dietary iodine intake during pregnancy showed no effect on maternal thyroid function or birth outcomes. However, iodine intake in the early postpartum period was markedly increased by the frequency of seaweed soup consumption.
PURPOSE: Given the high consumption of seaweed soup by pregnant and lactating Korean women, concerns have been raised about excessive iodine intake. We evaluated the effects of maternal iodine intake on maternal thyroid function and birth outcomes. We also evaluated iodine intake via seaweed soup during late pregnancy and the early postpartum period. METHODS: A total of 349 pregnant women of the Ideal Breast Milk cohort were recruited in late pregnancy, of whom 302 revisited after delivery. Three-day dietary records were assessed at each visit. Blood was collected for thyroid function test. Obstetrical and birth outcomes were obtained. RESULTS: The median dietary iodine intake was 459 μg/day (interquartile range [IQR] 326.5-647.4 μg/day) during pregnancy. Dietary iodine intake by quartile was not significantly associated with maternal thyroid status, or obstetrical or neonatal outcomes. However, the dietary iodine intake in the early postpartum period was 1759 μg/day (IQR 1026.7-2491.1 μg/day) because of a marked increase in seaweed soup consumption. Of all women, 25.8% consumed seaweed soup more than once over the 3 days of dietary records when pregnant, but the figure rose to 93.4% postpartum. Of postpartum women who consumed seaweed soup daily, the median dietary iodine intakes were 1355, 2394, and 3063 μg/day (soup at one, two, and three-or-four meals). CONCLUSIONS: In these iodine-replete pregnant women, dietary iodine intake during pregnancy showed no effect on maternal thyroid function or birth outcomes. However, iodine intake in the early postpartum period was markedly increased by the frequency of seaweed soup consumption.
Authors: Michael B Zimmermann; Małgorzata Gizak; Karen Abbott; Maria Andersson; John H Lazarus Journal: Lancet Diabetes Endocrinol Date: 2015-08-09 Impact factor: 32.069
Authors: Caroline Trumpff; Jean De Schepper; Jean Tafforeau; Herman Van Oyen; Johan Vanderfaeillie; Stefanie Vandevijvere Journal: J Trace Elem Med Biol Date: 2013-02-08 Impact factor: 3.849
Authors: Sofia Manousou; Maria Andersson; Robert Eggertsen; Sandra Hunziker; Lena Hulthén; Helena Filipsson Nyström Journal: Eur J Nutr Date: 2019-10-15 Impact factor: 5.614
Authors: Anna M Monaghan; Maria S Mulhern; Emeir M McSorley; J J Strain; Matthew Dyer; Edwin van Wijngaarden; Alison J Yeates Journal: Thyroid Res Date: 2021-06-07
Authors: Diane E Threapleton; Charles J P Snart; Claire Keeble; Amanda H Waterman; Elizabeth Taylor; Dan Mason; Stephen Reid; Rafaq Azad; Liam J B Hill; Sarah Meadows; Amanda McKillion; Nisreen A Alwan; Janet E Cade; Nigel A B Simpson; Paul M Stewart; Michael Zimmermann; John Wright; Dagmar Waiblinger; Mark Mon-Williams; Laura J Hardie; Darren C Greenwood Journal: Paediatr Perinat Epidemiol Date: 2020-09-01 Impact factor: 3.980