Literature DB >> 34521255

High Return to Sport in Patients Over 45 Years of Age Undergoing Osteochondral Allograft Transplantation for Isolated Chondral Defects in the Knee.

Danielle H Markus1, Eoghan T Hurley1, Jonathan D Haskel1, Amit K Manjunath1, Kirk A Campbell1, Guillem Gonzalez-Lomas1, Eric J Strauss1, Michael J Alaia1.   

Abstract

OBJECTIVE: The purpose of this study was to evaluate the efficacy of osteochondral allograft (OCA) in patients older than 45 years of age, particularly with respect to return to sport.
DESIGN: A retrospective review was performed to evaluate patients greater than 45 who underwent an OCA for a symptomatic osteochondral defect of the knee between June 2011 and January 2019.
RESULTS: Overall, there were 18 patients (76% male) that met our inclusion and exclusion criteria. Follow-up was attained in 14 of these patients (78%). The mean age of patients included was 52.6 years (48-57) with a mean of 37 months of follow-up (18-60). Visual Analogue Scale scores decreased significantly from the preoperative baseline to final follow-up (7.7 ± 1.7 vs. 2.0 ± 2.0, P < 0.01). Furthermore, the mean Visual Analogue Scale while playing sport was 3.4 ± 3.2, and the mean Knee Injury and Osteoarthritis Outcome Score was 77.5 ± 12.7 at final follow-up. Overall, 11 patients (78.6%) were able to return to their desired sport. No clinical failures were identified during the follow-up period.
CONCLUSION: In our series of patients 45 years and older who were treated with OCA for focal osteochondral injuries of the knee, we found a significant improvement in clinical outcome scores at a midterm follow-up of 37 months with no revision OCA procedures or conversion to any form of knee arthroplasty. In addition, a high percentage of patients were able to return to their preferred level of athletic activity.

Entities:  

Keywords:  age; osteochondral allograft; return to sport

Mesh:

Year:  2021        PMID: 34521255      PMCID: PMC8808893          DOI: 10.1177/19476035211046008

Source DB:  PubMed          Journal:  Cartilage        ISSN: 1947-6035            Impact factor:   3.117


  20 in total

1.  Cartilage injuries: a review of 31,516 knee arthroscopies.

Authors:  W W Curl; J Krome; E S Gordon; J Rushing; B P Smith; G G Poehling
Journal:  Arthroscopy       Date:  1997-08       Impact factor: 4.772

2.  Return to athletic activity after osteochondral allograft transplantation in the knee.

Authors:  Aaron J Krych; Catherine M Robertson; Riley J Williams
Journal:  Am J Sports Med       Date:  2012-02-07       Impact factor: 6.202

3.  Osteochondral Allograft Transplantation of the Knee in Patients Aged 40 Years and Older.

Authors:  Dean Wang; Vivek Kalia; Claire D Eliasberg; Tim Wang; Francesca R Coxe; Mollyann D Pais; Scott A Rodeo; Riley J Williams
Journal:  Am J Sports Med       Date:  2017-11-29       Impact factor: 6.202

4.  A prospective randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint in young athletes.

Authors:  Rimtautas Gudas; Romas J Kalesinskas; Vytautas Kimtys; Edgaras Stankevicius; Vytautas Toliusis; Giedrius Bernotavicius; Alfredas Smailys
Journal:  Arthroscopy       Date:  2005-09       Impact factor: 4.772

Review 5.  Outcomes Associated with Return to Sports Following Osteochondral Allograft Transplant in the Knee: a Scoping Review.

Authors:  John A Grant
Journal:  Curr Rev Musculoskelet Med       Date:  2019-06

6.  Fresh osteochondral allografting for steroid-associated osteonecrosis of the femoral condyles.

Authors:  Simon Görtz; Allison J De Young; William D Bugbee
Journal:  Clin Orthop Relat Res       Date:  2010-02-09       Impact factor: 4.176

7.  Long-term followup of the use of fresh osteochondral allografts for posttraumatic knee defects.

Authors:  Allan E Gross; Nadav Shasha; Phil Aubin
Journal:  Clin Orthop Relat Res       Date:  2005-06       Impact factor: 4.176

8.  Articular cartilage defects in 1,000 knee arthroscopies.

Authors:  Karin Hjelle; Eirik Solheim; Torbjørn Strand; Rune Muri; Mats Brittberg
Journal:  Arthroscopy       Date:  2002-09       Impact factor: 4.772

9.  The natural history of cartilage defects in people with knee osteoarthritis.

Authors:  M L Davies-Tuck; A E Wluka; Y Wang; A J Teichtahl; G Jones; C Ding; F M Cicuttini
Journal:  Osteoarthritis Cartilage       Date:  2007-08-16       Impact factor: 6.576

10.  Articular cartilage defects: study of 25,124 knee arthroscopies.

Authors:  W Widuchowski; J Widuchowski; T Trzaska
Journal:  Knee       Date:  2007-04-10       Impact factor: 2.199

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  1 in total

Review 1.  Osteochondral Allografts in Knee Surgery: Narrative Review of Evidence to Date.

Authors:  Wilson C Lai; Hunter L Bohlen; Nathan P Fackler; Dean Wang
Journal:  Orthop Res Rev       Date:  2022-08-11
  1 in total

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