Literature DB >> 15930924

Long-term followup of the use of fresh osteochondral allografts for posttraumatic knee defects.

Allan E Gross1, Nadav Shasha, Phil Aubin.   

Abstract

UNLABELLED: Posttraumatic osteochondral defects of the distal femur or proximal tibia pose a reconstructive challenge for the young active patient. Fresh osteochondral allografts have been used to reconstruct these defects and this report deals with the long-term clinical and radiographic follow-up in this patient population. This is a prospective nonrandomized study. Sixty patients with an average followup of 10 years received femoral condylar grafts. Twelve grafts failed, requiring removing of the graft in three patients and conversion to total knee replacement in nine patients. Kaplan-Meier survivorship showed 95% graft survival at 5 years and 85% at 10 years. Sixty-five patients received fresh osteochondral allografts to reconstruct the tibial plateau with an average followup of 11.8 years. In this group of patients, conversion to total knee arthroplasty was done in 21 patients at a mean interval of 9.7 years. Survival analysis revealed 95% survival at 5 years, 80% at 10 years, and 65% at 15 years. Through our long-term prospective study, we confirm the value of fresh osteochondral allografts to reconstruct articular defects of the knee in the young active patient. LEVEL OF EVIDENCE: Therapeutic study, Level II-1 (prospective cohort study). See the Guidelines for Authors for a complete description of levels of evidence.

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Year:  2005        PMID: 15930924     DOI: 10.1097/01.blo.0000165845.21735.05

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  77 in total

1.  Allogenic serum improves cold preservation of osteochondral allografts.

Authors:  Kenji Onuma; Ken Urabe; Kouji Naruse; Kentaro Uchida; Moritoshi Itoman
Journal:  Clin Orthop Relat Res       Date:  2011-11-18       Impact factor: 4.176

2.  Repair of massively defected hemi-joints using demineralized osteoarticular allografts with protected cartilage.

Authors:  Siming Li; Xiaohong Yang; Shenghui Tang; Xunmeng Zhang; Zhencheng Feng; Shuliang Cui
Journal:  J Mater Sci Mater Med       Date:  2015-08-30       Impact factor: 3.896

Review 3.  [Bridging posttraumatic bony defects. Established and new methods].

Authors:  M Schieker; W Mutschler
Journal:  Unfallchirurg       Date:  2006-09       Impact factor: 1.000

Review 4.  Management of knee articular cartilage injuries in athletes: chondroprotection, chondrofacilitation, and resurfacing.

Authors:  Iain R Murray; Michael T Benke; Bert R Mandelbaum
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-02-07       Impact factor: 4.342

5.  Material properties of fresh cold-stored allografts for osteochondral defects at 1 year.

Authors:  Anil S Ranawat; Armando F Vidal; Chris T Chen; Jonathan A Zelken; A Simon Turner; Riley J Williams
Journal:  Clin Orthop Relat Res       Date:  2008-06-05       Impact factor: 4.176

Review 6.  Chondrocyte apoptosis: implications for osteochondral allograft transplantation.

Authors:  Hubert T Kim; Margie S Teng; Alexis C Dang
Journal:  Clin Orthop Relat Res       Date:  2008-05-28       Impact factor: 4.176

7.  Fresh osteochondral allografts for posttraumatic knee defects: long-term followup.

Authors:  A E Gross; W Kim; F Las Heras; D Backstein; O Safir; K P H Pritzker
Journal:  Clin Orthop Relat Res       Date:  2008-05-09       Impact factor: 4.176

8.  50 years ago in CORR: Fate of osteochondral grafts Anthony F. DePalma, MD, Blackwell Sawyer MD, and J. David Hoffman MD, CORR 1962;22:217-234.

Authors:  Richard A Brand
Journal:  Clin Orthop Relat Res       Date:  2013-02-08       Impact factor: 4.176

Review 9.  [Partial and complete joint transplantation with fresh osteochondral allografts-the FLOCSAT concept].

Authors:  C Krettek; J-D Clausen; N Bruns; C Neunaber
Journal:  Unfallchirurg       Date:  2017-11       Impact factor: 1.000

10.  Radial head arthroplasty using a metatarsal osteochondral autograft.

Authors:  Kyeong-Jin Han; Kyung-Soo Oh; Nam-Su Chung; Yu Sang Lee; Sangjin Youn
Journal:  Int Orthop       Date:  2012-10-04       Impact factor: 3.075

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