Literature DB >> 34515588

The effect of analytical temperature on thromboelastography tracings in dogs.

Marie T Keith1, Nolan V Chalifoux1, Yekaterina Buriko1.   

Abstract

Viscoelastic testing methods such as thromboelastography (TEG) are becoming increasingly available to veterinarians in a clinical setting. TEG is useful in determining therapeutic transfusion needs and assessing global abnormalities of hemostasis of patients, given that it provides a more comprehensive assessment of coagulation than traditional tests. TEG is standardly performed at 37°C, which is considered a normal body temperature for human patients; however, 37°C is lower than normal body temperature for most canine patients. In an in vitro study, we investigated the potential effect that this difference in body temperature and test temperature might have on TEG results. Citrated blood samples were collected from clinically normal, as well as sick, dogs with various body temperatures. Samples were analyzed concurrently at the patient's body temperature and at 37°C. There was very high correlation between TEG performed at body temperature and at 37°C for R (min) and MA (mm), high correlation for K (min) and alpha angle (deg), and moderate correlation for LY30 (%) and LY60 (%). For canine patients with normal to mildly abnormal body temperatures, performance of TEG at the standard 37°C is acceptable.

Entities:  

Keywords:  blood coagulation tests; canine; hyperthermia; hypothermia; temperature; thromboelastography; viscoelastic

Mesh:

Year:  2021        PMID: 34515588      PMCID: PMC8689015          DOI: 10.1177/10406387211042922

Source DB:  PubMed          Journal:  J Vet Diagn Invest        ISSN: 1040-6387            Impact factor:   1.569


  14 in total

1.  Establishment of normal reference intervals in dogs using a viscoelastic point-of-care coagulation monitor and its comparison with thromboelastography.

Authors:  Yekaterina Buriko; Kenneth Drobatz; Deborah C Silverstein
Journal:  Vet Clin Pathol       Date:  2020-12-27       Impact factor: 1.180

2.  Effects of hypothermia on thrombelastography in patients undergoing cardiopulmonary bypass.

Authors:  S C Kettner; S A Kozek; J P Groetzner; C Gonano; A Schellongowski; M Kucera; M Zimpfer
Journal:  Br J Anaesth       Date:  1998-03       Impact factor: 9.166

3.  Partnership on Rotational ViscoElastic Test Standardization (PROVETS): evidence-based guidelines on rotational viscoelastic assays in veterinary medicine.

Authors:  Robert Goggs; Benjamin Brainard; Armelle M de Laforcade; Bente Flatland; Rita Hanel; Maureen McMichael; Bo Wiinberg
Journal:  J Vet Emerg Crit Care (San Antonio)       Date:  2014-01-14

4.  Hypothermic coagulopathy in trauma: effect of varying levels of hypothermia on enzyme speed, platelet function, and fibrinolytic activity.

Authors:  D D Watts; A Trask; K Soeken; P Perdue; S Dols; C Kaufmann
Journal:  J Trauma       Date:  1998-05

5.  Effects of rest temperature, contact activation, and sample technique on canine thrombelastography.

Authors:  Alan G Ralph; Benjamin M Brainard; Jennifer R Pittman; Danielle M Babski; Amie Koenig
Journal:  J Vet Emerg Crit Care (San Antonio)       Date:  2012-06

6.  Goal-directed Hemostatic Resuscitation of Trauma-induced Coagulopathy: A Pragmatic Randomized Clinical Trial Comparing a Viscoelastic Assay to Conventional Coagulation Assays.

Authors:  Eduardo Gonzalez; Ernest E Moore; Hunter B Moore; Michael P Chapman; Theresa L Chin; Arsen Ghasabyan; Max V Wohlauer; Carlton C Barnett; Denis D Bensard; Walter L Biffl; Clay C Burlew; Jeffrey L Johnson; Fredric M Pieracci; Gregory J Jurkovich; Anirban Banerjee; Christopher C Silliman; Angela Sauaia
Journal:  Ann Surg       Date:  2016-06       Impact factor: 12.969

7.  In vitro evaluation of the effect of hypothermia on coagulation in dogs via thromboelastography.

Authors:  Ryan Taggart; Brenda Austin; Eric Hans; Daniel Hogan
Journal:  J Vet Emerg Crit Care (San Antonio)       Date:  2012-04

8.  Temperature corrected thromboelastography in hypothermia: is it necessary?

Authors:  Ivan Cundrle; Vladimir Sramek; Martin Pavlik; Pavel Suk; Iveta Radouskova; Vaclav Zvonicek
Journal:  Eur J Anaesthesiol       Date:  2013-02       Impact factor: 4.330

9.  The effect of graded hypothermia (36 degrees C-32 degrees C) on hemostasis in anesthetized patients without surgical trauma.

Authors:  S C Kettner; C Sitzwohl; M Zimpfer; S A Kozek; A Holzer; C K Spiss; U M Illievich
Journal:  Anesth Analg       Date:  2003-06       Impact factor: 5.108

10.  Effect of temperature on thromboelastography and implications for clinical use in newborns undergoing therapeutic hypothermia.

Authors:  Katie R Forman; Edward Wong; Meanavy Gallagher; Robert McCarter; Naomi L C Luban; An N Massaro
Journal:  Pediatr Res       Date:  2014-02-12       Impact factor: 3.756

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