Berthyelle Pádova Nyland1, Cristiano Porcel Pereira1, Paulo Soares2, Denise Stolle da Luz Weiss2, Walter Luís Mikos3, João Armando Brancher1, Sérgio Vieira1, Andrea Freire4,5. 1. School of Life Sciences, Pontifícia Universidade Católica Do Paraná, Curitiba, Brasil. 2. Polytechnic School, Pontifícia Universidade Católica Do Paraná, Curitiba, Brasil. 3. Mechanical Engineering Department, Universidade Tecnológica Federal Do Paraná, Curitiba, Brasil. 4. School of Life Sciences, Pontifícia Universidade Católica Do Paraná, Curitiba, Brasil. andreavfreire@yahoo.com.br. 5. School of Dentistry- FAODO, Universidade Federal de Mato Grosso Do Sul, Av. Costa e Silva, S/N, Universitário, Campo Grande, MS, 79070-900, Brasil. andreavfreire@yahoo.com.br.
Abstract
OBJECTIVES: To evaluate the effect of strontium-containing titanium- and/or magnesium-doped phosphate bioactive glass on the control of dental erosion. MATERIALS AND METHODS: Fifty fragments of human enamel were divided into five groups: negative control, 45S5 bioglass, strontium-containing Ti-doped phosphate bioactive glass (PBG-Ti), strontium-containing Mg-doped phosphate bioactive glass (PBG-Mg), and strontium-containing Ti- and Mg-doped phosphate bioactive glass (PBG-TiMg). The specimens underwent cycles of erosive challenge twice daily for 5 days with 1 mL of citric acid for 2 min followed by 1 mL of the suspension with bioactive substances for 3 min. After the cycles, profilometry, roughness and microhardness testing, and scanning electron microscopy (SEM) were performed. The following statistical tests were used: one-way ANOVA (profile, roughness, and surface microhardness (%VMS) data variation), Tukey's HSD (%VMS), Games-Howell test (profilometry), Student's t test (roughness), and Pearson's correlation between the variables. RESULTS: The lower loss of enamel surface and lower %VMS was observed in the PBG-Mg and PBG-TiMg groups, and only the PBG-Mg group showed similar roughness between baseline and eroded areas (p > 0.05). On SEM micrographs, PBG-Ti and PBG-Mg groups showed lower apparent demineralization. CONCLUSION: All bioactive materials protected the enamel against erosion. However, strontium-containing phosphate bioactive glasses showed lower enamel loss, and the presence of Mg in these bioactive glasses provided a greater protective effect. CLINICAL RELEVANCE: Experimental strontium-containing phosphate bioactive glasses are effective in controlling enamel erosion. The results obtained in this study will guide the development of new dental products.
OBJECTIVES: To evaluate the effect of strontium-containing titanium- and/or magnesium-doped phosphate bioactive glass on the control of dental erosion. MATERIALS AND METHODS: Fifty fragments of human enamel were divided into five groups: negative control, 45S5 bioglass, strontium-containing Ti-doped phosphate bioactive glass (PBG-Ti), strontium-containing Mg-doped phosphate bioactive glass (PBG-Mg), and strontium-containing Ti- and Mg-doped phosphate bioactive glass (PBG-TiMg). The specimens underwent cycles of erosive challenge twice daily for 5 days with 1 mL of citric acid for 2 min followed by 1 mL of the suspension with bioactive substances for 3 min. After the cycles, profilometry, roughness and microhardness testing, and scanning electron microscopy (SEM) were performed. The following statistical tests were used: one-way ANOVA (profile, roughness, and surface microhardness (%VMS) data variation), Tukey's HSD (%VMS), Games-Howell test (profilometry), Student's t test (roughness), and Pearson's correlation between the variables. RESULTS: The lower loss of enamel surface and lower %VMS was observed in the PBG-Mg and PBG-TiMg groups, and only the PBG-Mg group showed similar roughness between baseline and eroded areas (p > 0.05). On SEM micrographs, PBG-Ti and PBG-Mg groups showed lower apparent demineralization. CONCLUSION: All bioactive materials protected the enamel against erosion. However, strontium-containing phosphate bioactive glasses showed lower enamel loss, and the presence of Mg in these bioactive glasses provided a greater protective effect. CLINICAL RELEVANCE: Experimental strontium-containing phosphate bioactive glasses are effective in controlling enamel erosion. The results obtained in this study will guide the development of new dental products.
Authors: T S Carvalho; P Colon; C Ganss; M C Huysmans; A Lussi; N Schlueter; G Schmalz; R P Shellis; A B Tveit; A Wiegand Journal: Clin Oral Investig Date: 2015-07-01 Impact factor: 3.573
Authors: Nadine Schlueter; Bennett T Amaechi; David Bartlett; Marília Afonso Rabelo Buzalaf; Thiago Saads Carvalho; Carolina Ganss; Anderson T Hara; Marie-Charlotte D N J M Huysmans; Adrian Lussi; Rebecca Moazzez; Alexandre Rezende Vieira; Nicola X West; Annette Wiegand; Alix Young; Frank Lippert Journal: Caries Res Date: 2019-10-14 Impact factor: 4.056