Ahmed Samir Bakry1, Hanadi Y Marghalani2, Omayma A Amin3, Junji Tagami4. 1. Operative Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudia Arabia; Conservative Dentistry Department, Faculty of Dentistry, Alexandria University, Egypt; Japan Society for the Promotion of Science, Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8549, Japan. Electronic address: drahmedbakry@gmail.com. 2. Operative Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudia Arabia. 3. Pharmaceutical Chemistry Department, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudia Arabia; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Alexandria University, Egypt. 4. Cariology and Operative Dentistry Department, Global Center of Excellence Program, Tokyo Medical and Dental University, Japan.
Abstract
OBJECTIVES: The current study is evaluating the effect of using a 45S5 bioglass paste and topical fluoride application on the cross sectional micro-hardness and the chemical surface changes of eroded enamel. METHODS: Enamel discs were obtained from the buccal surface of one hundred extracted human non-carious third molars. The enamel surfaces were ground flat and each disc was coated with two layers of acid resistant nail varnish except for an exposed treatment window (3mm×2mm) on the buccal surface of the tooth. All specimens were challenged for 60 min by orange juice (Tropicana, Chicago, USA) pH 3.85+0.5. The specimens were divided into four groups: the 45S5 bioglass paste group, fluoride gel group (5 min application), fluoride gel group (24h application) while the rest of specimens served as control. The cross-sectional micro-hardness of 20 specimens from each group was measured. Five specimens from each group had their top eroded enamel surfaces examined by SEM-EDS. One-way ANOVA was used to compare the cross-sectional micro-hardness of the three groups p<0.05. RESULTS: 45S5 bioglass paste application significantly improved the sub-surface eroded enamel when compared to fluoride and control specimens (p<0.05). CONCLUSION: 45S5 bioglass paste can efficiently improve the micro-hardness of the sub-surface eroded enamel surface. CLINICAL SIGNIFICANCE: The use of the 45S5 Bioglass paste can be used efficiently as a potent remineralizing agent for the sub-surface enamel lesions resulting from erosive challenges.
OBJECTIVES: The current study is evaluating the effect of using a 45S5 bioglass paste and topical fluoride application on the cross sectional micro-hardness and the chemical surface changes of eroded enamel. METHODS: Enamel discs were obtained from the buccal surface of one hundred extracted human non-carious third molars. The enamel surfaces were ground flat and each disc was coated with two layers of acid resistant nail varnish except for an exposed treatment window (3mm×2mm) on the buccal surface of the tooth. All specimens were challenged for 60 min by orange juice (Tropicana, Chicago, USA) pH 3.85+0.5. The specimens were divided into four groups: the 45S5 bioglass paste group, fluoride gel group (5 min application), fluoride gel group (24h application) while the rest of specimens served as control. The cross-sectional micro-hardness of 20 specimens from each group was measured. Five specimens from each group had their top eroded enamel surfaces examined by SEM-EDS. One-way ANOVA was used to compare the cross-sectional micro-hardness of the three groups p<0.05. RESULTS: 45S5 bioglass paste application significantly improved the sub-surface eroded enamel when compared to fluoride and control specimens (p<0.05). CONCLUSION: 45S5 bioglass paste can efficiently improve the micro-hardness of the sub-surface eroded enamel surface. CLINICAL SIGNIFICANCE: The use of the 45S5 Bioglass paste can be used efficiently as a potent remineralizing agent for the sub-surface enamel lesions resulting from erosive challenges.
Authors: Ahmed Samir Bakry; Mona Aly Abbassy; Hanin Fahad Alharkan; Sara Basuhail; Khalil Al-Ghamdi; Robert Hill Journal: Materials (Basel) Date: 2018-09-06 Impact factor: 3.623