K Reinholdt1, C Munk1, L T Thomsen1, C Dehlendorff2, B Carstensen3, M E Jørgensen3,4, S K Kjaer5,6. 1. Unit of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark. 2. Statistics and Data Analysis, Danish Cancer Society Research Center, Copenhagen, Denmark. 3. Steno Diabetes Center Copenhagen, Copenhagen, Denmark. 4. University of Southern Denmark, Odense, Denmark. 5. Unit of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark. susanne@cancer.dk. 6. Department of Gynecology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark. susanne@cancer.dk.
Abstract
AIMS: To estimate the incidence rates of genital warts (GWs) in women and men with type 1 diabetes compared to persons without diabetes. METHODS: In this nationwide registry-based cohort study, we included the entire population aged 15 to 49 years living in Denmark between 1996 and 2016. From national registries, we retrieved individual level information on diabetes status, diagnoses and treatment of GWs, and potential confounding variables. We used Poisson regression to model sex- and age-specific incidence rates of GWs in persons with type 1 diabetes and persons without diabetes. Based on the models, we computed sex-specific incidence rate ratios (IRRs) of GWs in persons with type 1 diabetes compared to persons without diabetes, overall and according to age. RESULTS: The analysis included 3,514,824 persons without type 2 diabetes and no GW diagnoses before baseline. The incidence rate of GWs in persons with type 1 diabetes was higher than in those without diabetes, both among women (IRR = 1.59; 95% CI, 1.42-1.78) and men (IRR = 1.36; 95% CI, 1.25-1.48). The pattern of increased incidence rates of GWs in persons with type 1 diabetes was seen at all ages. CONCLUSIONS: Persons with type 1 diabetes have higher incidence rates of GWs than persons without diabetes. This supports the importance of HPV vaccination of young girls and boys with type 1 diabetes.
AIMS: To estimate the incidence rates of genital warts (GWs) in women and men with type 1 diabetes compared to persons without diabetes. METHODS: In this nationwide registry-based cohort study, we included the entire population aged 15 to 49 years living in Denmark between 1996 and 2016. From national registries, we retrieved individual level information on diabetes status, diagnoses and treatment of GWs, and potential confounding variables. We used Poisson regression to model sex- and age-specific incidence rates of GWs in persons with type 1 diabetes and persons without diabetes. Based on the models, we computed sex-specific incidence rate ratios (IRRs) of GWs in persons with type 1 diabetes compared to persons without diabetes, overall and according to age. RESULTS: The analysis included 3,514,824 persons without type 2 diabetes and no GW diagnoses before baseline. The incidence rate of GWs in persons with type 1 diabetes was higher than in those without diabetes, both among women (IRR = 1.59; 95% CI, 1.42-1.78) and men (IRR = 1.36; 95% CI, 1.25-1.48). The pattern of increased incidence rates of GWs in persons with type 1 diabetes was seen at all ages. CONCLUSIONS: Persons with type 1 diabetes have higher incidence rates of GWs than persons without diabetes. This supports the importance of HPV vaccination of young girls and boys with type 1 diabetes.
Authors: Mélanie Drolet; Marc Brisson; Elizabeth Maunsell; Eduardo L Franco; François Coutlée; Alex Ferenczy; Sam Ratnam; William Fisher; James A Mansi Journal: Sex Transm Dis Date: 2011-10 Impact factor: 2.830
Authors: Signe Bollerup; Birgitte Baldur-Felskov; Maria Blomberg; Louise Baandrup; Christian Dehlendorff; Susanne K Kjaer Journal: Sex Transm Dis Date: 2016-04 Impact factor: 2.830
Authors: Christopher C Patterson; Valma Harjutsalo; Joachim Rosenbauer; Andreas Neu; Ondrej Cinek; Torild Skrivarhaug; Birgit Rami-Merhar; Gyula Soltesz; Jannet Svensson; Roger C Parslow; Conxa Castell; Eugen J Schoenle; Polly J Bingley; Gisela Dahlquist; Przemysława K Jarosz-Chobot; Dalė Marčiulionytė; Edna F Roche; Ulrike Rothe; Natasa Bratina; Constantin Ionescu-Tirgoviste; Ilse Weets; Mirjana Kocova; Valentino Cherubini; Natasa Rojnic Putarek; Carine E deBeaufort; Mira Samardzic; Anders Green Journal: Diabetologia Date: 2018-11-28 Impact factor: 10.122
Authors: Iain M Carey; Julia A Critchley; Stephen DeWilde; Tess Harris; Fay J Hosking; Derek G Cook Journal: Diabetes Care Date: 2018-01-12 Impact factor: 19.112
Authors: Julia A Critchley; Iain M Carey; Tess Harris; Stephen DeWilde; Fay J Hosking; Derek G Cook Journal: Diabetes Care Date: 2018-08-13 Impact factor: 19.112