Literature DB >> 34491770

Emergency CT misdiagnosis in acute aortic syndrome.

John G Dreisbach1,2, Jonathan Cl Rodrigues3, Giles Roditi2.   

Abstract

OBJECTIVES: This cross-sectional study assessed the accuracy of emergency CT reports at presentation in acute aortic syndrome (AAS).
METHODS: Retrospective identification of cases of AAS presenting within a large health board with three acute hospitals receiving adult patients between January 2013 and December 2016. CT studies and reports at presentation were reviewed for discrepancies related to diagnosis, complications and classification by two cardiovascular radiologists. The specialist interest of the original reporters, clinically suspected diagnosis at referral for CT and technical adequacy of the scans were also assessed. False-positive diagnoses were identified and evaluated separately.
RESULTS: Among 88 consecutive confirmed cases of AAS at least one discrepancy was identified in 31% (n = 27), including failure to identify or misinterpretation of the AAS itself in 15% (n = 13), haemorrhage in 13% (n = 11), branch involvement in 9% (n = 8), and misclassification in 3% (n = 3). All discrepancies occurred among the 80% (n = 70) of cases reported by radiologists without specialist cardiovascular interest. 26% (n = 23/88) of AAS cases were not clinically suspected at referral for CT and although this was associated with suboptimal protocols, only 51% of CT scans among suspected cases were technically adequate. Seven false-positive diagnoses were identified, three of which related to motion artefact.
CONCLUSION: Significant discrepancies are common in the emergency CT assessment of positive cases AAS and this study highlights important pitfalls in CT technique and interpretation. The absence of discrepancies among radiologists with specialist cardiovascular interest suggests both suspected and confirmed cases warrant urgent specialist review. ADVANCES IN KNOWLEDGE: CT angiography is central to the diagnosis of AAS; however, significant radiology discrepancies are common among non-specialists. This study highlights important pitfalls in both CT technique as well as interpretation and supports routine specialist cardiovascular imaging input in the emergency assessment of AAS.

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Year:  2021        PMID: 34491770      PMCID: PMC9328041          DOI: 10.1259/bjr.20201294

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.629


  27 in total

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Authors:  Loren F Hiratzka; George L Bakris; Joshua A Beckman; Robert M Bersin; Vincent F Carr; Donald E Casey; Kim A Eagle; Luke K Hermann; Eric M Isselbacher; Ella A Kazerooni; Nicholas T Kouchoukos; Bruce W Lytle; Dianna M Milewicz; David L Reich; Souvik Sen; Julie A Shinn; Lars G Svensson; David M Williams
Journal:  Circulation       Date:  2010-03-16       Impact factor: 29.690

2.  Prevalence and factors associated with false positive suspicion of acute aortic syndrome: experience in a patient population transferred to a specialized aortic treatment center.

Authors:  Chad E Raymond; Bhuvnesh Aggarwal; Paul Schoenhagen; Damon M Kralovic; Kristopher Kormos; David Holloway; Venu Menon
Journal:  Cardiovasc Diagn Ther       Date:  2013-12

3.  Motion artifact resulting in a false positive CT angiogram for a presumed aortic dissection.

Authors:  Riny Karras; Marco Ricci; Thomas A Salerno; Edward Gologorsky
Journal:  J Card Surg       Date:  2011-02-07       Impact factor: 1.620

4.  Aortic arch dissection: a controversy of classification.

Authors:  Jason K Lempel; Aletta Ann Frazier; Jean Jeudy; Seth J Kligerman; Randall Schultz; Hammed A Ninalowo; Elliott K Gozansky; Bartley Griffith; Charles S White
Journal:  Radiology       Date:  2014-03-07       Impact factor: 11.105

5.  Preliminary development of a clinical decision rule for acute aortic syndromes.

Authors:  Andrew J Lovy; Eran Bellin; Jeffrey M Levsky; David Esses; Linda B Haramati
Journal:  Am J Emerg Med       Date:  2013-09-20       Impact factor: 2.469

6.  Miss rate of lung cancer on the chest radiograph in clinical practice.

Authors:  L G Quekel; A G Kessels; R Goei; J M van Engelshoven
Journal:  Chest       Date:  1999-03       Impact factor: 9.410

7.  Incidence, risk factors, outcome and projected future burden of acute aortic dissection.

Authors:  Dominic P J Howard; Ediri Sideso; Ashok Handa; Peter M Rothwell
Journal:  Ann Cardiothorac Surg       Date:  2014-05

8.  Challenges in delivering computed tomography coronary angiography as the first-line test for stable chest pain.

Authors:  John G Dreisbach; Edward D Nicol; Carl A Roobottom; Simon Padley; Giles Roditi
Journal:  Heart       Date:  2017-11-14       Impact factor: 5.994

9.  Acute retrograde type A aortic dissection: morphologic analysis and clinical implications.

Authors:  Paul D DiMusto; Brooks L Rademacher; Jennifer L Philip; Shahab A Akhter; Christopher B Goodavish; Nilto C De Oliveira; Paul C Tang
Journal:  J Surg Res       Date:  2017-02-27       Impact factor: 2.192

Review 10.  Error and discrepancy in radiology: inevitable or avoidable?

Authors:  Adrian P Brady
Journal:  Insights Imaging       Date:  2016-12-07
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