Literature DB >> 34490838

Strategies to improve pharmacogenomic-guided treatment options for patients with β-hemoglobinopathies.

George P Patrinos1,2,3, David H K Chui4, Ross C Hardison5,6, Martin H Steinberg4.   

Abstract

Entities:  

Keywords:  clinical trials; genomic variants; pharmacogenomics; sickle cell disease; therapeutics; β-hemoglobinopathies

Mesh：

Substances：

Year:  2021        PMID： 34490838      PMCID： PMC9306350          DOI： 10.1080/17474086.2021.1977117

Source DB:  PubMed          Journal:  Expert Rev Hematol        ISSN： 1747-4094            Impact factor:   2.819


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  19 in total

1.  Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach.

Authors:  Belinda Giardine; Joseph Borg; Douglas R Higgs; Kenneth R Peterson; Sjaak Philipsen; Donna Maglott; Belinda K Singleton; David J Anstee; A Nazli Basak; Barnaby Clark; Flavia C Costa; Paula Faustino; Halyna Fedosyuk; Alex E Felice; Alain Francina; Renzo Galanello; Monica V E Gallivan; Marianthi Georgitsi; Richard J Gibbons; Piero C Giordano; Cornelis L Harteveld; James D Hoyer; Martin Jarvis; Philippe Joly; Emmanuel Kanavakis; Panagoula Kollia; Stephan Menzel; Webb Miller; Kamran Moradkhani; John Old; Adamantia Papachatzopoulou; Manoussos N Papadakis; Petros Papadopoulos; Sonja Pavlovic; Lucia Perseu; Milena Radmilovic; Cathy Riemer; Stefania Satta; Iris Schrijver; Maja Stojiljkovic; Swee Lay Thein; Jan Traeger-Synodinos; Ray Tully; Takahito Wada; John S Waye; Claudia Wiemann; Branka Zukic; David H K Chui; Henri Wajcman; Ross C Hardison; George P Patrinos
Journal:  Nat Genet       Date:  2011-03-20       Impact factor: 38.330

2.  Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: risks and benefits up to 9 years of treatment.

Authors:  Martin H Steinberg; Franca Barton; Oswaldo Castro; Charles H Pegelow; Samir K Ballas; Abdullah Kutlar; Eugene Orringer; Rita Bellevue; Nancy Olivieri; James Eckman; Mala Varma; Gloria Ramirez; Brian Adler; Wally Smith; Timothy Carlos; Kenneth Ataga; Laura DeCastro; Carolyn Bigelow; Yogen Saunthararajah; Margaret Telfer; Elliott Vichinsky; Susan Claster; Susan Shurin; Kenneth Bridges; Myron Waclawiw; Duane Bonds; Michael Terrin
Journal:  JAMA       Date:  2003-04-02       Impact factor: 56.272

3.  KLF10 gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in β-hemoglobinopathy patients.

Authors:  Joseph Borg; Marios Phylactides; Marina Bartsakoulia; Christina Tafrali; Carsten Lederer; Alexander E Felice; Adamantia Papachatzopoulou; Alexandra Kourakli; Eleana F Stavrou; Soteroula Christou; Jun Hou; Sophia Karkabouna; Christina Lappa-Manakou; Zeliha Ozgur; Wilfred van Ijcken; Marieke von Lindern; Frank G Grosveld; Marianthi Georgitsi; Marina Kleanthous; Sjaak Philipsen; George P Patrinos
Journal:  Pharmacogenomics       Date:  2012-10       Impact factor: 2.533

Review 4.  Molecular basis of β thalassemia and potential therapeutic targets.

Authors:  Swee Lay Thein
Journal:  Blood Cells Mol Dis       Date:  2017-06-20       Impact factor: 3.039

5.  The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: A 17.5 year follow-up.

Authors:  Martin H Steinberg; William F McCarthy; Oswaldo Castro; Samir K Ballas; F Danny Armstrong; Wally Smith; Kenneth Ataga; Paul Swerdlow; Abdullah Kutlar; Laura DeCastro; Myron A Waclawiw
Journal:  Am J Hematol       Date:  2010-06       Impact factor: 10.047

Review 6.  Pharmacogenomics and therapeutics of hemoglobinopathies.

Authors:  George P Patrinos; Frank G Grosveld
Journal:  Hemoglobin       Date:  2008       Impact factor: 0.849

7.  Application of Economic Evaluation to Assess Feasibility for Reimbursement of Genomic Testing as Part of Personalized Medicine Interventions.

Authors:  Stavros Simeonidis; Stefania Koutsilieri; Athanassios Vozikis; David N Cooper; Christina Mitropoulou; George P Patrinos
Journal:  Front Pharmacol       Date:  2019-08-02       Impact factor: 5.810

8.  Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene.

Authors:  Patrick R Sosnay; Karen R Siklosi; Fredrick Van Goor; Kyle Kaniecki; Haihui Yu; Neeraj Sharma; Anabela S Ramalho; Margarida D Amaral; Ruslan Dorfman; Julian Zielenski; David L Masica; Rachel Karchin; Linda Millen; Philip J Thomas; George P Patrinos; Mary Corey; Michelle H Lewis; Johanna M Rommens; Carlo Castellani; Christopher M Penland; Garry R Cutting
Journal:  Nat Genet       Date:  2013-08-25       Impact factor: 38.330

9.  The UK Biobank resource with deep phenotyping and genomic data.

Authors:  Clare Bycroft; Colin Freeman; Desislava Petkova; Gavin Band; Lloyd T Elliott; Kevin Sharp; Allan Motyer; Damjan Vukcevic; Olivier Delaneau; Jared O'Connell; Adrian Cortes; Samantha Welsh; Alan Young; Mark Effingham; Gil McVean; Stephen Leslie; Naomi Allen; Peter Donnelly; Jonathan Marchini
Journal:  Nature       Date:  2018-10-10       Impact factor: 49.962

10.  Clinically relevant updates of the HbVar database of human hemoglobin variants and thalassemia mutations.

Authors:  Belinda M Giardine; Philippe Joly; Serge Pissard; Henri Wajcman; David H K Chui; Ross C Hardison; George P Patrinos
Journal:  Nucleic Acids Res       Date:  2021-01-08       Impact factor: 19.160
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