| Literature DB >> 34478015 |
Danielle Giovenco1,2, Audrey Pettifor3, Kimberly A Powers3, Lisa Hightow-Weidman4, Brian W Pence3, Jessie K Edwards3, Katherine Gill5, Jennifer F Morton6, Ariane van der Straten7,8, Connie Celum6,9, Linda-Gail Bekker5.
Abstract
Effective strategies to support PrEP adherence among adolescent girls and young women (AGYW) are needed. We examined PrEP use disclosure and its effect on adherence among 200 AGYW ages 16-25 initiating PrEP in South Africa to help inform these strategies. We estimated the relative prevalence of high adherence (intracellular tenofovir-diphosphate concentration ≥ 700 fmol/punch) 3- and 6-months after PrEP initiation among those who disclosed vs. did not disclose their PrEP use, both overall and by age. Most AGYW disclosed to a parent (58%), partner (58%), or friend (81%) by month 6. We did not observe a strong effect of disclosure on adherence overall; however, among younger AGYW (≤ 18 years), those who disclosed to a parent were 6.8 times as likely to have high adherence at month 6 than those who did not (95% CI 1.02, 45.56). More work is needed to understand parents' roles as allies and identify ways peers and partners can motivate PrEP use for AGYW.Entities:
Keywords: Adolescent girls and young women; Disclosure; HIV prevention; PrEP; Pre-exposure prophylaxis
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Year: 2021 PMID： 34478015 PMCID： PMC8891396 DOI： 10.1007/s10461-021-03455-x
Source DB: PubMed Journal: AIDS Behav ISSN： 1090-7165