Literature DB >> 34473321

Evaluation of Antidiabetic Properties of Adenosma Bracteosum Bonati Extracts in Mice with Streptozotocin-Induced Diabetes.

Giau Van Vo1,2, Paul C Guest3, Ngoc Hong Nguyen4.   

Abstract

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia. Traditional medicinal plants with antidiabetic properties can be used as drugs or dietary adjuvants to existing therapies. This chapter presents the preparation of aqueous and ethanol extracts of Adenosma bracteosum Bonati (A. bracteosum) and evaluation of these for antioxidant and α-glucosidase inhibition activities in vitro. In addition, we tested the extracts and the purified A. bracteosum compound (isoscutellarein 8-O-β-D-glucopyranoside) for antihyperglycemic effects in glucose-loaded hyperglycemic and streptozotocin (STZ)-induced diabetic mice.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Antidiabetic; Extract; Isolated compound; STZ; Streptozotocin; α-glucosidase inhibition

Mesh：

Substances：

Year:  2022        PMID： 34473321     DOI： 10.1007/978-1-0716-1558-4_10

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  7 in total

1.  Qualitative phytochemical screening and in vitro antimicrobial effects of methanol stem bark extract of Ficus thonningii (Moraceae).

Authors:  H Usman; Fi Abdulrahman; A Usman
Journal:  Afr J Tradit Complement Altern Med       Date:  2009-05-07

2.  Preclinical and clinical results regarding the effects of a plant-based antidiabetic formulation versus well established antidiabetic molecules.

Authors:  Anca Ungurianu; Oana Şeremet; Elvira Gagniuc; Octavian Tudor Olaru; Claudia Guţu; Daniela Grǎdinaru; Constantin Ionescu-Tȋrgovişte; Denisa Marginǎ; Rucsandra Dǎnciulescu-Miulescu
Journal:  Pharmacol Res       Date:  2019-11-04       Impact factor: 7.658

3.  Preliminary study of sex hormones of medical importance in Bangladeshi plants.

Authors:  A Mannan; K Ahmad
Journal:  Bangladesh Med Res Counc Bull       Date:  1978-12

4.  Hemolytic and cytotoxic properties of saponin purified from Holothuria leucospilota sea cucumber.

Authors:  Mozhgan Soltani; Kazem Parivar; Javad Baharara; Mohammad Amin Kerachian; Javad Asili
Journal:  Rep Biochem Mol Biol       Date:  2014-10

Review 5.  Role of Insulin Resistance in the Alzheimer's Disease Progression.

Authors:  Thuy Trang Nguyen; Qui Thanh Hoai Ta; Thi Thuy Dung Nguyen; Thi Thuy Le; Van Giau Vo
Journal:  Neurochem Res       Date:  2020-04-20       Impact factor: 3.996

6.  Trends in incidence of total or type 2 diabetes: systematic review.

Authors:  Dianna J Magliano; Rakibul M Islam; Elizabeth L M Barr; Edward W Gregg; Meda E Pavkov; Jessica L Harding; Maryam Tabesh; Digsu N Koye; Jonathan E Shaw
Journal:  BMJ       Date:  2019-09-11

Review 7.  Understanding glycaemic control and current approaches for screening antidiabetic natural products from evidence-based medicinal plants.

Authors:  Chintha Lankatillake; Tien Huynh; Daniel A Dias
Journal:  Plant Methods       Date:  2019-09-07       Impact factor: 4.993
  7 in total

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