Kishor Lakshminarayanan1, Rakshit Shah2. 1. Department of Sensors and Biomedical Engineering, Vellore Institute of Technology, Vellore, Tamil Nadu, 632014, India. kishor.ln@vit.ac.in. 2. Department of Chemical and Biomedical Engineering, Cleveland State University, Cleveland, OH, USA.
Abstract
BACKGROUND: The aim of this study is to investigate the changes in median nerve and transverse carpal ligament (TCL)-formed carpal arch morphology as possible risk factors for median nerve entrapment in women with type 2 diabetes. METHODS: The distal carpal tunnel was imaged using ultrasound in 30 female subjects (15 with type 2 diabetes, 15 controls). The morphological parameters of the median nerve and carpal arch were derived from the ultrasound images. One-way analysis of variance (ANOVA) was used for statistical analysis. RESULTS: Diabetic women had an enlarged median nerve area (p < 0.05), salong with a maller carpal arch size, as indicated by a reduced palmar bowing index of the TCL (p < 0.05), and arch area (p < 0.05) than controls. The distance from the median nerve centroid to the volar boundary of the TCL was reduced in diabetic women (p < 0.05) compared to the controls. CONCLUSIONS: Women with type 2 diabetes have reduced available space for the median nerve within the carpal arch due to the enlarged nerve and reduced arch size, making the median nerve more susceptible to entrapment within the tunnel. The current study shows that presence of diabetes increases the risk of median nerve entrapment in women and requires early detection of symptoms to avoid carpal tunnel syndrome.
BACKGROUND: The aim of this study is to investigate the changes in median nerve and transverse carpal ligament (TCL)-formed carpal arch morphology as possible risk factors for median nerve entrapment in women with type 2 diabetes. METHODS: The distal carpal tunnel was imaged using ultrasound in 30 female subjects (15 with type 2 diabetes, 15 controls). The morphological parameters of the median nerve and carpal arch were derived from the ultrasound images. One-way analysis of variance (ANOVA) was used for statistical analysis. RESULTS: Diabetic women had an enlarged median nerve area (p < 0.05), salong with a maller carpal arch size, as indicated by a reduced palmar bowing index of the TCL (p < 0.05), and arch area (p < 0.05) than controls. The distance from the median nerve centroid to the volar boundary of the TCL was reduced in diabetic women (p < 0.05) compared to the controls. CONCLUSIONS: Women with type 2 diabetes have reduced available space for the median nerve within the carpal arch due to the enlarged nerve and reduced arch size, making the median nerve more susceptible to entrapment within the tunnel. The current study shows that presence of diabetes increases the risk of median nerve entrapment in women and requires early detection of symptoms to avoid carpal tunnel syndrome.
Authors: Jefferson Becker; Daniel B Nora; Irenio Gomes; Fernanda F Stringari; Rafael Seitensus; Juliana S Panosso; João C Ehlers Journal: Clin Neurophysiol Date: 2002-09 Impact factor: 3.708
Authors: P J Dyck; K M Kratz; J L Karnes; W J Litchy; R Klein; J M Pach; D M Wilson; P C O'Brien; L J Melton; F J Service Journal: Neurology Date: 1993-04 Impact factor: 9.910