OBJECTIVES: The aim of this study is to identify gender, high body mass index (BMI), age and diabetes mellitus (DM) as independent risk factors (RF) for carpal tunnel syndrome (CTS) and to analyse the strength of association of these factors, both globally and in individual subgroups. METHODS: We performed a case-control study with 791 CTS cases and 981 controls. Patients were selected from those referred to nerve conduction studies and electromyography in 3 university hospitals and two private services. We calculated the odds ratio between the two groups to analyse the RF. Possible sources of bias were studied using stratified and multivariate analyses. RESULTS: The mean BMI and age were greater in the case group than in the control. Female gender, BMI>30, age of 41-60 years and DM were significantly more frequent in the case group. Males tend to have a more severe CTS and DM was a significant RF for bilateral lesions. Stratified analysis showed female gender, obesity and age of 41-60 years as independent RF. DM, when stratified by BMI category, was not significantly associated with CTS. CONCLUSIONS: Our study confirms that female gender, obesity and age are independent RF for CTS. DM may be a weak RF, especially among women.
OBJECTIVES: The aim of this study is to identify gender, high body mass index (BMI), age and diabetes mellitus (DM) as independent risk factors (RF) for carpal tunnel syndrome (CTS) and to analyse the strength of association of these factors, both globally and in individual subgroups. METHODS: We performed a case-control study with 791 CTS cases and 981 controls. Patients were selected from those referred to nerve conduction studies and electromyography in 3 university hospitals and two private services. We calculated the odds ratio between the two groups to analyse the RF. Possible sources of bias were studied using stratified and multivariate analyses. RESULTS: The mean BMI and age were greater in the case group than in the control. Female gender, BMI>30, age of 41-60 years and DM were significantly more frequent in the case group. Males tend to have a more severe CTS and DM was a significant RF for bilateral lesions. Stratified analysis showed female gender, obesity and age of 41-60 years as independent RF. DM, when stratified by BMI category, was not significantly associated with CTS. CONCLUSIONS: Our study confirms that female gender, obesity and age are independent RF for CTS. DM may be a weak RF, especially among women.
Authors: David F Ten Cate; Nick Glaser; Jolanda J Luime; King H Lam; Johannes W G Jacobs; Ruud Selles; Johanna M W Hazes; Marietta Bertleff Journal: Clin Rheumatol Date: 2014-06-24 Impact factor: 2.980
Authors: Stefano Mattioli; Alberto Baldasseroni; Massimo Bovenzi; Stefania Curti; Robin M T Cooke; Giuseppe Campo; Pietro G Barbieri; Rinaldo Ghersi; Marco Broccoli; Maria Pia Cancellieri; Anna Maria Colao; Marco Dell'omo; Pirous Fateh-Moghadam; Flavia Franceschini; Serenella Fucksia; Paolo Galli; Fabriziomaria Gobba; Roberto Lucchini; Anna Mandes; Teresa Marras; Carla Sgarrella; Stefano Borghesi; Mauro Fierro; Francesca Zanardi; Gianpiero Mancini; Francesco S Violante Journal: BMC Public Health Date: 2009-09-16 Impact factor: 3.295