Mei Tian1,2, Yasuyoshi Watanabe3, Keon Wook Kang4, Koji Murakami5, Arturo Chiti6,7, Ignasi Carrio8, A Cahid Civelek9, Jianhua Feng10, Yuankai Zhu11,12, Rui Zhou11,12, Shuang Wu11,12, Junming Zhu13, Yao Ding14, Kai Zhang3, Hong Zhang15,16,17,18. 1. Department of Nuclear Medicine and PET Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China. meitian@zju.edu.cn. 2. Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, 310009, China. meitian@zju.edu.cn. 3. Laboratory for Pathophysiological and Health Science, RIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo, 650-0047, Japan. 4. Department of Nuclear Medicine, Seoul National University Hospital, Seoul, 03080, Korea. 5. Department of Radiology, Juntendo University Hospital, Tokyo, 113-8431, Japan. 6. Department of Biomedical Sciences, Humanitas University, 20090 Pieve Emanuele, Milan, Italy. 7. IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089, Rozzano, Milan, Italy. 8. Department of Nuclear Medicine, Hospital Sant Pau, Autonomous University of Barcelona, 08025, Barcelona, Spain. 9. Department of Radiology and Radiological Science, Johns Hopkins Medicine, Baltimore, MD, 21287, USA. 10. Department of Pediatrics, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 310009, China. 11. Department of Nuclear Medicine and PET Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China. 12. Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, 310009, China. 13. Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 310009, China. 14. Department of Neurology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 310009, China. 15. Department of Nuclear Medicine and PET Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China. hzhang21@zju.edu.cn. 16. Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, 310009, China. hzhang21@zju.edu.cn. 17. The College of Biomedical Engineering and Instrument Science of Zhejiang University, Hangzhou, 310007, China. hzhang21@zju.edu.cn. 18. Key Laboratory for Biomedical Engineering of Ministry of Education, Zhejiang University, Hangzhou, 310007, China. hzhang21@zju.edu.cn.
Abstract
PURPOSE: Positron emission tomography (PET) with 18F-fluorodeoxyglucose ([18F]-FDG) has been increasingly applied in precise localization of epileptogenic focus in epilepsy patients, including pediatric patients. The aim of this international consensus is to provide the guideline and specific considerations for [18F]-FDG PET in pediatric patients affected by epilepsy. METHODS: An international, multidisciplinary task group is formed, and the guideline for brain [18F]-FDG PET/CT in pediatric epilepsy patients has been discussed and approved, which include but not limited to the clinical indications, patient preparation, radiopharmaceuticals and administered activities, image acquisition, image processing, image interpretation, documentation and reporting, etc. CONCLUSION: This is the first international consensus and practice guideline for brain [18F]-FDG PET/CT in pediatric epilepsy patients. It will be an international standard for this purpose in clinical practice.
PURPOSE: Positron emission tomography (PET) with 18F-fluorodeoxyglucose ([18F]-FDG) has been increasingly applied in precise localization of epileptogenic focus in epilepsy patients, including pediatric patients. The aim of this international consensus is to provide the guideline and specific considerations for [18F]-FDG PET in pediatric patients affected by epilepsy. METHODS: An international, multidisciplinary task group is formed, and the guideline for brain [18F]-FDG PET/CT in pediatric epilepsy patients has been discussed and approved, which include but not limited to the clinical indications, patient preparation, radiopharmaceuticals and administered activities, image acquisition, image processing, image interpretation, documentation and reporting, etc. CONCLUSION: This is the first international consensus and practice guideline for brain [18F]-FDG PET/CT in pediatric epilepsy patients. It will be an international standard for this purpose in clinical practice.
Authors: Jörg Wellmer; Carlos M Quesada; Lars Rothe; Christian E Elger; Christian G Bien; Horst Urbach Journal: Epilepsia Date: 2013-10-07 Impact factor: 5.864
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