Literature DB >> 34435504

Predicting immune checkpoint inhibitor response with mathematical modeling.

Joseph D Butner1, Zhihui Wang1,2,3.   

Abstract

Entities:  

Keywords:  clinical translation; immunotherapy; mathematical modeling; mechanistic modeling; predictive modeling; treatment optimization

Mesh：

Substances：

Year:  2021        PMID： 34435504      PMCID： PMC8451515          DOI： 10.2217/imt-2021-0209

Source DB:  PubMed          Journal:  Immunotherapy        ISSN： 1750-743X            Impact factor:   4.040


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  25 in total

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2.  Cancer treatment and survivorship statistics, 2019.

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3.  A validated mathematical model of cell-mediated immune response to tumor growth.

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4.  Macrophage T lymphocyte interactions in the anti-tumor immune response: a mathematical model.

Authors:  R J De Boer; P Hogeweg; H F Dullens; R A De Weger; W Den Otter
Journal:  J Immunol       Date:  1985-04       Impact factor: 5.422

5.  Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial.

Authors:  Antoni Ribas; Igor Puzanov; Reinhard Dummer; Dirk Schadendorf; Omid Hamid; Caroline Robert; F Stephen Hodi; Jacob Schachter; Anna C Pavlick; Karl D Lewis; Lee D Cranmer; Christian U Blank; Steven J O'Day; Paolo A Ascierto; April K S Salama; Kim A Margolin; Carmen Loquai; Thomas K Eigentler; Tara C Gangadhar; Matteo S Carlino; Sanjiv S Agarwala; Stergios J Moschos; Jeffrey A Sosman; Simone M Goldinger; Ronnie Shapira-Frommer; Rene Gonzalez; John M Kirkwood; Jedd D Wolchok; Alexander Eggermont; Xiaoyun Nicole Li; Wei Zhou; Adriane M Zernhelt; Joy Lis; Scot Ebbinghaus; S Peter Kang; Adil Daud
Journal:  Lancet Oncol       Date:  2015-06-23       Impact factor: 41.316

6.  How to calculate the dose of chemotherapy.

Authors:  Howard Gurney
Journal:  Br J Cancer       Date:  2002-04-22       Impact factor: 7.640

7.  A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition.

Authors:  Chang Gong; Oleg Milberg; Bing Wang; Paolo Vicini; Rajesh Narwal; Lorin Roskos; Aleksander S Popel
Journal:  J R Soc Interface       Date:  2017-09       Impact factor: 4.118

8.  How to schedule VEGF and PD-1 inhibitors in combination cancer therapy?

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Review 9.  Cancer Immunotherapy Dosing: A Pharmacokinetic/Pharmacodynamic Perspective.

Authors:  Félicien Le Louedec; Fanny Leenhardt; Clémence Marin; Étienne Chatelut; Alexandre Evrard; Joseph Ciccolini
Journal:  Vaccines (Basel)       Date:  2020-10-31

10.  A mathematical model for the quantification of a patient's sensitivity to checkpoint inhibitors and long-term tumour burden.

Authors:  Joseph D Butner; Zhihui Wang; Dalia Elganainy; Karine A Al Feghali; Marija Plodinec; George A Calin; Prashant Dogra; Sara Nizzero; Javier Ruiz-Ramírez; Geoffrey V Martin; Hussein A Tawbi; Caroline Chung; Eugene J Koay; James W Welsh; David S Hong; Vittorio Cristini
Journal:  Nat Biomed Eng       Date:  2021-01-04       Impact factor: 29.234
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