| Literature DB >> 34417759 |
Dongmei Zhang1, Mengshi Wu2, Minmin Xiong2, Congjian Xu3, Peng Xiang2, Xiaomin Zhong4.
Abstract
Recently an explosion in the discovery of long noncoding RNAs (lncRNAs) was obtained by high-throughput sequencing. Genome-wide transcriptome analyses, in conjugation with research for epigenetic modifications of chromatins, identified a novel type of non-protein coding transcripts longer than 200 nucleotides named lncRNAs . They are gradually emerging as functional and critical participants in many physiological processes. Here we gave an overview of the characteristics, biological functions, and working mechanism for this new class of noncoding RNA molecules.Entities:
Keywords: Cancer; Epigenetic; Long noncoding RNAs; Stem cell
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Year: 2021 PMID: 34417759 DOI: 10.1007/978-1-0716-1697-0_23
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745