Literature DB >> 34417752

Characterization of Circular RNAs.

Yang Zhang1, Li Yang2,3, Ling-Ling Chen4,5.   

Abstract

Accumulated lines of evidence have revealed that a large number of circular RNAs are produced in transcriptomes from fruit fly to mouse and human. Unlike linear RNAs shaped with 5' cap and 3' tail, circular RNAs are characterized by covalently closed loop structures without open terminals, thus required specific treatments for their identification and validation. Here, we describe a detailed pipeline for the characterization of circular RNAs. It has been successfully applied to the study of circular intronic RNAs (ciRNAs) derived from intron lariats and circular RNAs (circRNAs) produced from back spliced exons in human.
© 2021. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Circular RNAs; Divergent PCR; Northern blot; PAGE; RNA fractionation; RNase R; ciRNAs; circRNAs

Mesh：

Substances：

Year:  2021        PMID： 34417752     DOI： 10.1007/978-1-0716-1697-0_16

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  39 in total

1.  Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures.

Authors:  H L Sanger; G Klotz; D Riesner; H J Gross; A K Kleinschmidt
Journal:  Proc Natl Acad Sci U S A       Date:  1976-11       Impact factor: 11.205

2.  Scrambled exons.

Authors:  J M Nigro; K R Cho; E R Fearon; S E Kern; J M Ruppert; J D Oliner; K W Kinzler; B Vogelstein
Journal:  Cell       Date:  1991-02-08       Impact factor: 41.582

3.  The hepatitis delta (delta) virus possesses a circular RNA.

Authors:  A Kos; R Dijkema; A C Arnberg; P H van der Meide; H Schellekens
Journal:  Nature       Date:  1986 Oct 9-15       Impact factor: 49.962

4.  Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.

Authors:  Agnieszka Rybak-Wolf; Christin Stottmeister; Petar Glažar; Marvin Jens; Natalia Pino; Sebastian Giusti; Mor Hanan; Mikaela Behm; Osnat Bartok; Reut Ashwal-Fluss; Margareta Herzog; Luisa Schreyer; Panagiotis Papavasileiou; Andranik Ivanov; Marie Öhman; Damian Refojo; Sebastian Kadener; Nikolaus Rajewsky
Journal:  Mol Cell       Date:  2015-04-23       Impact factor: 17.970

5.  Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity.

Authors:  Chu-Xiao Liu; Xiang Li; Fang Nan; Shan Jiang; Xiang Gao; Si-Kun Guo; Wei Xue; Yange Cui; Kaige Dong; Huihua Ding; Bo Qu; Zhaocai Zhou; Nan Shen; Li Yang; Ling-Ling Chen
Journal:  Cell       Date:  2019-04-25       Impact factor: 41.582

6.  Some yeast mitochondrial RNAs are circular.

Authors:  A C Arnberg; G J Van Ommen; L A Grivell; E F Van Bruggen; P Borst
Journal:  Cell       Date:  1980-02       Impact factor: 41.582

7.  Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.

Authors:  Monika Piwecka; Petar Glažar; Luis R Hernandez-Miranda; Sebastian Memczak; Susanne A Wolf; Agnieszka Rybak-Wolf; Andrei Filipchyk; Filippos Klironomos; Cledi Alicia Cerda Jara; Pascal Fenske; Thorsten Trimbuch; Vera Zywitza; Mireya Plass; Luisa Schreyer; Salah Ayoub; Christine Kocks; Ralf Kühn; Christian Rosenmund; Carmen Birchmeier; Nikolaus Rajewsky
Journal:  Science       Date:  2017-08-10       Impact factor: 47.728

8.  Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.

Authors:  Xintian You; Irena Vlatkovic; Ana Babic; Tristan Will; Irina Epstein; Georgi Tushev; Güney Akbalik; Mantian Wang; Caspar Glock; Claudia Quedenau; Xi Wang; Jingyi Hou; Hongyu Liu; Wei Sun; Sivakumar Sambandan; Tao Chen; Erin M Schuman; Wei Chen
Journal:  Nat Neurosci       Date:  2015-02-25       Impact factor: 24.884

9.  Splicing with inverted order of exons occurs proximal to large introns.

Authors:  C Cocquerelle; P Daubersies; M A Majérus; J P Kerckaert; B Bailleul
Journal:  EMBO J       Date:  1992-03       Impact factor: 11.598

10.  Circular transcripts of the testis-determining gene Sry in adult mouse testis.

Authors:  B Capel; A Swain; S Nicolis; A Hacker; M Walter; P Koopman; P Goodfellow; R Lovell-Badge
Journal:  Cell       Date:  1993-06-04       Impact factor: 41.582
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