Literature DB >> 34414264

Factors Influencing Willingness to Use Human Immunodeficiency Virus Preexposure Prophylaxis Among Transgender Women in India.

Venkatesan Chakrapani1, Simran Shaikh2, Visvanathan Arumugam2, Umesh Chawla2, Sonal Mehta2.   

Abstract

Purpose: High levels of human immunodeficiency virus (HIV) prevalence and inconsistent condom use among transgender women in India highlight the need for additional effective HIV prevention methods like preexposure prophylaxis (PrEP). We examined the extent of and factors influencing willingness to use PrEP among trans women in India.
Methods: Between June and August 2017, we conducted a cross-sectional survey among 360 trans women recruited through community-based organizations in six cities. We assessed PrEP knowledge, condom use, attitudes toward PrEP (after providing information on PrEP), preferences in PrEP pricing and access venues, discrimination experiences, and the likelihood of using PrEP. Logistic regression analyses were conducted.
Results: Participants' median age was 26 years; 50.7% had not completed high school, and 24.8% engaged in sex work. Only 17.1% reported having heard of PrEP before the survey, and 80.6% reported that they would definitely use PrEP. Trans women in sex work had 28 times higher odds of reporting willingness to use PrEP than those not in sex work (adjusted odds ratio [aOR]=28.9, 95% confidence interval [CI]=8.79-95.16, p<0.001). When compared with trans women who did not experience discrimination, the odds of reporting willingness to use PrEP was lower among trans women who had experienced discrimination from health care providers (aOR=0.25, 95% CI=0.06-0.97, p=0.04) and family members (aOR=0.08, 95% CI=0.05-0.14, p<0.001).
Conclusion: Willingness to use PrEP was high among trans women, especially those in sex work, despite identified barriers (e.g., discrimination experiences). To promote PrEP uptake among at-risk trans women, the steps needed are as follows: increasing awareness about PrEP; providing easy-to-understand information on PrEP's effectiveness, side effects and interactions between PrEP and hormones; training health care providers on PrEP and cultural competency; and reducing stigmas related to PrEP use and HIV. PrEP implementation research projects to identify effective PrEP delivery strategies are urgently needed to reduce the disproportionate HIV burden among trans women in India. Copyright 2021, Mary Ann Liebert, Inc., publishers.

Entities:  

Keywords:  HIV; India; PrEP; preexposure prophylaxis; trans women; transgender

Year:  2021        PMID: 34414264      PMCID: PMC8363996          DOI: 10.1089/trgh.2019.0076

Source DB:  PubMed          Journal:  Transgend Health        ISSN: 2380-193X


  27 in total

Review 1.  How Stigma Surrounding the Use of HIV Preexposure Prophylaxis Undermines Prevention and Pleasure: A Call to Destigmatize "Truvada Whores".

Authors:  Sarah K Calabrese; Kristen Underhill
Journal:  Am J Public Health       Date:  2015-08-13       Impact factor: 9.308

2.  Awareness and Willingness to Use Pre-exposure Prophylaxis (PrEP) Among Men Who Have Sex with Men and Transgender Women in Brazil.

Authors:  Brenda Hoagland; Raquel B De Boni; Ronaldo I Moreira; José Valdez Madruga; Esper G Kallas; Silvia Pereira Goulart; Natalia Cerqueira; Thiago S Torres; Paula M Luz; Nilo Martinez Fernandes; Albert Y Liu; Beatriz Grinsztejn; Valdilea G Veloso
Journal:  AIDS Behav       Date:  2017-05

3.  Ethical Implications of Social Stigma Associated with the Promotion and Use of Pre-Exposure Prophylaxis for HIV Prevention.

Authors:  Patrick D Herron
Journal:  LGBT Health       Date:  2016-02-09       Impact factor: 4.151

4.  Acceptability of HIV Pre-Exposure Prophylaxis (PrEP) and Implementation Challenges Among Men Who Have Sex with Men in India: A Qualitative Investigation.

Authors:  Venkatesan Chakrapani; Peter A Newman; Murali Shunmugam; Shruta Mengle; Jarvis Varghese; Ruban Nelson; Shalini Bharat
Journal:  AIDS Patient Care STDS       Date:  2015-09-08       Impact factor: 5.078

5.  Acceptability of pre-exposure prophylaxis among men who have sex with men and transgender women in Northern Thailand.

Authors:  Daniel Yang; Chonlisa Chariyalertsak; Antika Wongthanee; Surinda Kawichai; Kriengkrai Yotruean; Pongpun Saokhieo; Thomas Guadamuz; Voravit Suwanvanichkij; Chris Beyrer; Suwat Chariyalertsak
Journal:  PLoS One       Date:  2013-10-08       Impact factor: 3.240

6.  Prioritizing Risk in Preparation for a Demonstration Project: A Mixed Methods Feasibility Study of Oral Pre-Exposure Prophylaxis (PREP) among Female Sex Workers in South India.

Authors:  Sushena Reza-Paul; Lisa Lazarus; Monika Doshi; Syed Hafeez Ur Rahman; Manjula Ramaiah; Raviprakash Maiya; Venugopal Ms; K T Venukumar; Sundar Sundararaman; Marissa Becker; Stephen Moses; Robert Lorway
Journal:  PLoS One       Date:  2016-11-23       Impact factor: 3.240

Review 7.  How acceptable are antiretrovirals for the prevention of sexually transmitted HIV?: A review of research on the acceptability of oral pre-exposure prophylaxis and treatment as prevention.

Authors:  Ingrid Young; Lisa McDaid
Journal:  AIDS Behav       Date:  2014-02

8.  Antiretroviral pre-exposure prophylaxis: A new opportunity to slow HIV spread in India.

Authors:  Kenneth H Mayer; Nomita Chandhiok; Beena Thomas
Journal:  Indian J Med Res       Date:  2016-02       Impact factor: 2.375

Review 9.  Global Epidemiology of HIV Infection and Related Syndemics Affecting Transgender People.

Authors:  Tonia Poteat; Ayden Scheim; Jessica Xavier; Sari Reisner; Stefan Baral
Journal:  J Acquir Immune Defic Syndr       Date:  2016-08-15       Impact factor: 3.731

10.  High Willingness to Use HIV Pre-Exposure Prophylaxis Among Transgender Women in Argentina.

Authors:  Virginia Zalazar; Inés Arístegui; Thomas Kerr; Brandon D L Marshall; Marcela Romero; Omar Sued; M Eugenia Socías
Journal:  Transgend Health       Date:  2016-12-01
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