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Literature DB >> 26270298

How Stigma Surrounding the Use of HIV Preexposure Prophylaxis Undermines Prevention and Pleasure: A Call to Destigmatize "Truvada Whores".

Abstract

Antiretroviral preexposure prophylaxis (PrEP; emtricitabine and tenofovir disoproxil fumarate [Truvada]) prevents HIV without penalizing sexual pleasure, and may even enhance pleasure (e.g., by reducing HIV-related anxiety). However, concern about sexual risk behavior increasing with PrEP use (risk compensation) and corresponding stereotypes of promiscuity may undermine PrEP's preventive potential. In this commentary, we review literature on sexual behavior change accompanying PrEP use, discuss risk compensation concerns and the "Truvada whore" stereotype as PrEP barriers, question the appropriateness of restricting PrEP access because of risk compensation, and consider sexual pleasure as a benefit of PrEP, an acceptable motive for seeking PrEP, and a core element of health. It is essential for science to trump stereotypes and sex-negative messaging in guiding decision-making affecting PrEP access and uptake.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2015 PMID： 26270298 PMCID： PMC4566537 DOI： 10.2105/AJPH.2015.302816

Source DB: PubMed Journal: Am J Public Health ISSN： 0090-0036 Impact factor: 9.308

69 in total

1. Risky business: safety regulations, risks compensation, and individual behavior.

Authors: J Hedlund
Journal: Inj Prev Date: 2000-06 Impact factor: 2.399

2. Preexposure prophylaxis and predicted condom use among high-risk men who have sex with men.

Authors: Sarit A Golub; William Kowalczyk; Corina L Weinberger; Jeffrey T Parsons
Journal: J Acquir Immune Defic Syndr Date: 2010-08 Impact factor: 3.731

3. Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study.

Authors: Robert M Grant; Peter L Anderson; Vanessa McMahan; Albert Liu; K Rivet Amico; Megha Mehrotra; Sybil Hosek; Carlos Mosquera; Martin Casapia; Orlando Montoya; Susan Buchbinder; Valdilea G Veloso; Kenneth Mayer; Suwat Chariyalertsak; Linda-Gail Bekker; Esper G Kallas; Mauro Schechter; Juan Guanira; Lane Bushman; David N Burns; James F Rooney; David V Glidden
Journal: Lancet Infect Dis Date: 2014-07-22 Impact factor: 25.071

4. Attitudes Towards PrEP and Anticipated Condom Use Among Concordant HIV-Negative and HIV-Discordant Male Couples.

Authors: Colleen C Hoff; Deepalika Chakravarty; Anja E Bircher; Chadwick K Campbell; Kirk Grisham; Torsten B Neilands; Patrick A Wilson; Shari Dworkin
Journal: AIDS Patient Care STDS Date: 2015-06-09 Impact factor: 5.078

5. The Truvada wars.

Authors: Julia Belluz
Journal: BMJ Date: 2014-06-24

6. Knowledge of pre-exposure prophylaxis (PrEP) for HIV prevention among men who have sex with men in Denver, Colorado.

Authors: Alia A Al-Tayyib; Mark W Thrun; Jason S Haukoos; N Eugene Walls
Journal: AIDS Behav Date: 2014-04

Review 7. Pre-exposure prophylaxis state of the science: empirical analogies for research and implementation.

Authors: Sarit A Golub; Don Operario; Pamina M Gorbach
Journal: Curr HIV/AIDS Rep Date: 2010-11 Impact factor: 5.071

8. HIV providers' perceived barriers and facilitators to implementing pre-exposure prophylaxis in care settings: a qualitative study.

Authors: Douglas Krakower; Norma Ware; Jennifer A Mitty; Kevin Maloney; Kenneth H Mayer
Journal: AIDS Behav Date: 2014-09

9. Biomarker validation of reports of recent sexual activity: results of a randomized controlled study in Zimbabwe.

Authors: Alexandra M Minnis; Markus J Steiner; Maria F Gallo; Lee Warner; Marcia M Hobbs; Ariane van der Straten; Tsungai Chipato; Maurizio Macaluso; Nancy S Padian
Journal: Am J Epidemiol Date: 2009-09-09 Impact factor: 4.897

10. No evidence of sexual risk compensation in the iPrEx trial of daily oral HIV preexposure prophylaxis.

Authors: Julia L Marcus; David V Glidden; Kenneth H Mayer; Albert Y Liu; Susan P Buchbinder; K Rivet Amico; Vanessa McMahan; Esper Georges Kallas; Orlando Montoya-Herrera; Jose Pilotto; Robert M Grant
Journal: PLoS One Date: 2013-12-18 Impact factor: 3.240

101 in total

1. Does HIV Pre-Exposure Prophylaxis Modify the Effect of Partnership Characteristics on Condom Use? A Cross-Sectional Study of Sexual Partnerships Among Men Who Have Sex with Men in San Francisco, California.

Authors: Maximo R Prescott; Jaclyn Hern; Maya Petersen; Glenn-Milo Santos
Journal: AIDS Patient Care STDS Date: 2019-04 Impact factor: 5.078

2. HIV-Related Communication and Safe Sex Practices among Heterosexual Black Men: A Qualitative Report.

Authors: Keosha T Bond; Victoria Frye; Malik Cupid; Debbie Lucy; Beryl A Koblin
Journal: J Black Sex Relatsh Date: 2018

Review 3. Evolving Models and Ongoing Challenges for HIV Preexposure Prophylaxis Implementation in the United States.

Authors: Kenneth H Mayer; Philip A Chan; Rupa R Patel; Charlene A Flash; Douglas S Krakower
Journal: J Acquir Immune Defic Syndr Date: 2018-02-01 Impact factor: 3.731

4. Potential Healthcare Insurance and Provider Barriers to Pre-Exposure Prophylaxis Utilization Among Young Men Who Have Sex with Men.

Authors: Sarah J Marks; Roland C Merchant; Melissa A Clark; Tao Liu; Joshua G Rosenberger; Jose Bauermeister; Kenneth H Mayer
Journal: AIDS Patient Care STDS Date: 2017-11 Impact factor: 5.078

5. Social network intervention to increase pre-exposure prophylaxis (PrEP) awareness, interest, and use among African American men who have sex with men.

Authors: Jeffrey A Kelly; Yuri A Amirkhanian; Jennifer L Walsh; Kevin D Brown; Katherine G Quinn; Andrew E Petroll; Broderick M Pearson; A Noel Rosado; Thom Ertl
Journal: AIDS Care Date: 2020-03-13

6. Pre-Exposure Prophylaxis (PrEP) Use and Condomless Anal Sex: Evidence of Risk Compensation in a Cohort of Young Men Who Have Sex with Men.

Authors: Michael E Newcomb; Kevin Moran; Brian A Feinstein; Emily Forscher; Brian Mustanski
Journal: J Acquir Immune Defic Syndr Date: 2018-04-01 Impact factor: 3.731

7. Experiences of Anticipated and Enacted Pre-exposure Prophylaxis (PrEP) Stigma Among Latino MSM in Los Angeles.

Authors: Ronald A Brooks; Amanda Landrian; Omar Nieto; Anne Fehrenbacher
Journal: AIDS Behav Date: 2019-07

8. Brief Report: PrEPTECH: A Telehealth-Based Initiation Program for HIV Pre-exposure Prophylaxis in Young Men of Color Who Have Sex With Men. A Pilot Study of Feasibility.

Authors: Oliver N Refugio; Mabel M Kimble; Cara L Silva; James E Lykens; Christian Bannister; Jeffrey D Klausner
Journal: J Acquir Immune Defic Syndr Date: 2019-01-01 Impact factor: 3.731

9. The Impact of Pre-exposure Prophylaxis on Sexual Well-Being Among Men Who Have Sex with Men.

Authors: Hanne M L Zimmermann; Lisa R Postma; Roel C A Achterbergh; Thijs Reyniers; Maarten F Schim van der Loeff; Maria Prins; Henry J C de Vries; Elske Hoornenborg; Udi Davidovich
Journal: Arch Sex Behav Date: 2021-02-22

10. How Do Gay and Bisexual Men Make Up for Missed PrEP Doses, and What Impact Does Missing a Dose Have on Their Subsequent Sexual Behavior?

Authors: Christian Grov; Alexa B D'Angelo; Anthony W P Flynn; Javier Lopez-Rios; David W Pantalone; Ian W Holloway; Thomas H F Whitfield; Jeffrey T Parsons
Journal: AIDS Educ Prev Date: 2018-08