Tanis R Fenton1,2, Roseann Nasser3, Dianne Creighton4, Seham Elmrayed5, Selphee Tang6,7, Chelsia Gillis5, Belal Alshaikh5,4. 1. Community Health Sciences, O'Brien Institute of Public Health, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. TFenton@ucalgary.ca. 2. Nutrition Services, Alberta Health Services, Calgary, AB, Canada. TFenton@ucalgary.ca. 3. Nutrition and Food Services, Saskatchewan Health Authority, Regina, SK, Canada. 4. Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. 5. Community Health Sciences, O'Brien Institute of Public Health, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. 6. Alberta Children's Hospital Neonatal Follow-up Clinic, Alberta Health Services, Calgary, AB, Canada. 7. Department of Obstetrics and Gynecology, Alberta Health Services, Calgary, AB, Canada.
Abstract
OBJECTIVES: To identify the prevalence and risk factors for childhood overweight and obesity (OWO) at 3-year corrected age in children born <1500 g <29 weeks gestation. STUDY DESIGN: A multicentre retrospective cohort study for preterm infants admitted to neonatal intensive care units between 2001 and 2014. RESULTS: Data were available for 911 (89.4%) of the 1019 infants who met the inclusion criteria. Of them, 22 (2.4%) had OWO. There were no associations between OWO and being small for gestational age (RR = 1.3, 95% confidence interval (CI): 0.3-5.4) or weight <10th percentile at 36 weeks (RR = 1.1, 95% CI: 0.4-2.8). OWO was associated with low maternal education (RR = 7.4, 95% CI: 2.1-26), maternal diabetes (RR = 5.2, 95% CI: 1.9-15) and neonatal brain injury (RR = 4.9, 95% CI: 1.8-14). Adjusting for concurrent child weight at 3 years of age resulted in an overadjustment bias. CONCLUSION: Small size at birth or at 36 weeks gestation in extremely preterm infants is not associated with increased risk of early childhood overgrowth or obesity. CLINICAL TRIAL REGISTRATION: NCT03064022.
OBJECTIVES: To identify the prevalence and risk factors for childhood overweight and obesity (OWO) at 3-year corrected age in children born <1500 g <29 weeks gestation. STUDY DESIGN: A multicentre retrospective cohort study for preterm infants admitted to neonatal intensive care units between 2001 and 2014. RESULTS: Data were available for 911 (89.4%) of the 1019 infants who met the inclusion criteria. Of them, 22 (2.4%) had OWO. There were no associations between OWO and being small for gestational age (RR = 1.3, 95% confidence interval (CI): 0.3-5.4) or weight <10th percentile at 36 weeks (RR = 1.1, 95% CI: 0.4-2.8). OWO was associated with low maternal education (RR = 7.4, 95% CI: 2.1-26), maternal diabetes (RR = 5.2, 95% CI: 1.9-15) and neonatal brain injury (RR = 4.9, 95% CI: 1.8-14). Adjusting for concurrent child weight at 3 years of age resulted in an overadjustment bias. CONCLUSION: Small size at birth or at 36 weeks gestation in extremely preterm infants is not associated with increased risk of early childhood overgrowth or obesity. CLINICAL TRIAL REGISTRATION: NCT03064022.
Authors: Tanis R Fenton; Barbara Cormack; Dena Goldberg; Roseann Nasser; Belal Alshaikh; Misha Eliasziw; William W Hay; Angela Hoyos; Diane Anderson; Frank Bloomfield; Ian Griffin; Nicholas Embleton; Niels Rochow; Sarah Taylor; Thibault Senterre; Richard J Schanler; Seham Elmrayed; Sharon Groh-Wargo; David Adamkin; Prakesh S Shah Journal: J Perinatol Date: 2020-03-25 Impact factor: 2.521
Authors: Laura Cloostermans; Wanda Wendel-Vos; Gerda Doornbos; Bethany Howard; Cora Lynn Craig; Mika Kivimäki; Adam G Tabak; Barbara J Jefferis; Kimmo Ronkainen; Wendy J Brown; Susan H S J Picavet; Yoav Ben-Shlomo; Jari Antero Laukkanen; Jussi Kauhanen; Wanda J E Bemelmans Journal: Int J Behav Nutr Phys Act Date: 2015-12-01 Impact factor: 6.457
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