| Literature DB >> 32214217 |
Tanis R Fenton1,2, Barbara Cormack3, Dena Goldberg4, Roseann Nasser5, Belal Alshaikh6,7, Misha Eliasziw8, William W Hay9, Angela Hoyos10, Diane Anderson11, Frank Bloomfield3, Ian Griffin12, Nicholas Embleton13, Niels Rochow14, Sarah Taylor15, Thibault Senterre16, Richard J Schanler17, Seham Elmrayed6, Sharon Groh-Wargo18, David Adamkin19, Prakesh S Shah20.
Abstract
Preterm infants are increasingly diagnosed as having "extrauterine growth restriction" (EUGR) or "postnatal growth failure" (PGF). Usually EUGR/PGF is diagnosed when weight is <10th percentile at either discharge or 36-40 weeks postmenstrual age. The reasons why the phrases EUGR/PGF are unhelpful include, they: (i) are not predictive of adverse outcome; (ii) are based only on weight without any consideration of head or length growth, proportionality, body composition, or genetic potential; (iii) ignore normal postnatal weight loss; (iv) are usually assessed prior to growth slowing of the reference fetus, around 36-40 weeks, and (v) are usually based on an arbitrary statistical growth percentile cut-off. Focus on EUGR/PGF prevalence may benefit with better attention to nutrition but may also harm with nutrition delivery above infants' actual needs. In this paper, we highlight challenges associated with such arbitrary cut-offs and opportunities for further refinement of understanding growth and nutritional needs of preterm neonates.Entities:
Year: 2020 PMID: 32214217 DOI: 10.1038/s41372-020-0658-5
Source DB: PubMed Journal: J Perinatol ISSN: 0743-8346 Impact factor: 2.521