Literature DB >> 34394720

Postpartum atypical hemolytic uremic syndrome: Evaluating thrombotic microangiopathy in the pregnant woman.

S So1, E Fischer1, M Gangadharan Komala1,2, B Bose1,2.   

Abstract

Acute kidney injury in women during pregnancy and the puerperium is often ascribed to hypertensive complications of pregnancy, especially pre-eclampsia. However, rarer causes, including atypical hemolytic uremic syndrome (aHUS) can be triggered by pregnancy. We present a case of a woman with post-partum acute kidney injury due to aHUS, which was successfully treated with the C5a inhibitor eculizumab. We also present a summary of the evaluation and management of thrombotic microangiopathy in pregnancy.
© The Author(s) 2020.

Entities:  

Keywords:  Acute kidney injury; hemolytic uremic syndrome; postpartum; pregnancy; renal failure; thrombotic microangiopathies

Year:  2020        PMID: 34394720      PMCID: PMC8358242          DOI: 10.1177/1753495X20926043

Source DB:  PubMed          Journal:  Obstet Med        ISSN: 1753-495X


  24 in total

Review 1.  Differentiation between severe HELLP syndrome and thrombotic microangiopathy, thrombotic thrombocytopenic purpura and other imitators.

Authors:  O Pourrat; R Coudroy; F Pierre
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2015-03-25       Impact factor: 2.435

2.  Pregnancy-related acute renal failure in eastern India.

Authors:  Nalini Arora; Kirti Mahajan; Narayan Jana; Abhijit Taraphder
Journal:  Int J Gynaecol Obstet       Date:  2010-09-25       Impact factor: 3.561

3.  A retrospective study of pregnancy-associated atypical hemolytic uremic syndrome.

Authors:  Ana Huerta; Emilia Arjona; Jose Portoles; Paula Lopez-Sanchez; Cristina Rabasco; Mario Espinosa; Teresa Cavero; Miquel Blasco; Mercedes Cao; Joaquin Manrique; Virginia Cabello-Chavez; Marta Suñer; Manuel Heras; Xavier Fulladosa; Lara Belmar; Amparo Sempere; Carmen Peralta; Lorena Castillo; Alvaro Arnau; Manuel Praga; Santiago Rodriguez de Cordoba
Journal:  Kidney Int       Date:  2017-09-12       Impact factor: 10.612

4.  Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria.

Authors:  Richard J Kelly; Britta Höchsmann; Jeff Szer; Austin Kulasekararaj; Sophie de Guibert; Alexander Röth; Ilene C Weitz; Elina Armstrong; Antonio M Risitano; Christopher J Patriquin; Louis Terriou; Petra Muus; Anita Hill; Michelle P Turner; Hubert Schrezenmeier; Regis Peffault de Latour
Journal:  N Engl J Med       Date:  2015-09-10       Impact factor: 91.245

5.  Syndromes of thrombotic microangiopathy associated with pregnancy.

Authors:  James N George; Carla M Nester; Jennifer J McIntosh
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2015

Review 6.  Complement inhibition keeps mothers calm and avoids fetal rejection.

Authors:  Guillermina Girardi
Journal:  Immunol Invest       Date:  2008       Impact factor: 3.657

7.  Genetics and outcome of atypical hemolytic uremic syndrome: a nationwide French series comparing children and adults.

Authors:  Véronique Fremeaux-Bacchi; Fadi Fakhouri; Arnaud Garnier; Frank Bienaimé; Marie-Agnès Dragon-Durey; Stéphanie Ngo; Bruno Moulin; Aude Servais; François Provot; Lionel Rostaing; Stéphane Burtey; Patrick Niaudet; Georges Deschênes; Yvon Lebranchu; Julien Zuber; Chantal Loirat
Journal:  Clin J Am Soc Nephrol       Date:  2013-01-10       Impact factor: 8.237

8.  Pregnant Woman with Atypical Hemolytic Uremic Syndrome Delivered a Healthy Newborn under Eculizumab Treatment.

Authors:  Erol Demir; Halil Yazici; Yasemin Ozluk; Isin Kilicaslan; Aydin Turkmen
Journal:  Case Rep Nephrol Dial       Date:  2016-12-20

9.  Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome: A case report.

Authors:  Alice Gustavsen; Lillemor Skattum; Grethe Bergseth; Bjorg Lorentzen; Yngvar Floisand; Vidar Bosnes; Tom Eirik Mollnes; Andreas Barratt-Due
Journal:  Medicine (Baltimore)       Date:  2017-03       Impact factor: 1.889

Review 10.  Atypical hemolytic uremic syndrome.

Authors:  David Kavanagh; Tim H Goodship; Anna Richards
Journal:  Semin Nephrol       Date:  2013-11       Impact factor: 5.299

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