Literature DB >> 34374183

Population-level management of type 1 diabetes via continuous glucose monitoring and algorithm-enabled patient prioritization: Precision health meets population health.

Johannes O Ferstad1, Jacqueline J Vallon1, Daniel Jun1, Angela Gu2, Anastasiya Vitko2, Dianelys P Morales1, Jeannine Leverenz3, Ming Yeh Lee3, Brianna Leverenz3, Christos Vasilakis4, Esli Osmanlliu3,5, Priya Prahalad3,6, David M Maahs3,6,7, Ramesh Johari1,6, David Scheinker1,3,8.   

Abstract

OBJECTIVE: To develop and scale algorithm-enabled patient prioritization to improve population-level management of type 1 diabetes (T1D) in a pediatric clinic with fixed resources, using telemedicine and remote monitoring of patients via continuous glucose monitor (CGM) data review. RESEARCH DESIGN AND METHODS: We adapted consensus glucose targets for T1D patients using CGM to identify interpretable clinical criteria to prioritize patients for weekly provider review. The criteria were constructed to manage the number of patients reviewed weekly and identify patients who most needed provider contact. We developed an interactive dashboard to display CGM data relevant for the patients prioritized for review.
RESULTS: The introduction of the new criteria and interactive dashboard was associated with a 60% reduction in the mean time spent by diabetes team members who remotely and asynchronously reviewed patient data and contacted patients, from 3.2 ± 0.20 to 1.3 ± 0.24 min per patient per week. Given fixed resources for review, this corresponded to an estimated 147% increase in weekly clinic capacity. Patients who qualified for and received remote review (n = 58) have associated 8.8 percentage points (pp) (95% CI = 0.6-16.9 pp) greater time-in-range (70-180 mg/dl) glucoses compared to 25 control patients who did not qualify at 12 months after T1D onset.
CONCLUSIONS: An algorithm-enabled prioritization of T1D patients with CGM for asynchronous remote review reduced provider time spent per patient and was associated with improved time-in-range.
© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  continuous glucose monitoring; population management; remote monitoring

Mesh:

Substances:

Year:  2021        PMID: 34374183      PMCID: PMC8635792          DOI: 10.1111/pedi.13256

Source DB:  PubMed          Journal:  Pediatr Diabetes        ISSN: 1399-543X            Impact factor:   3.409


  19 in total

1.  Adjusting insulin doses in patients with type 1 diabetes who use insulin pump and continuous glucose monitoring: Variations among countries and physicians.

Authors:  Revital Nimri; Eyal Dassau; Tomer Segall; Ido Muller; Natasa Bratina; Olga Kordonouri; Rachel Bello; Torben Biester; Klemen Dovc; Ariel Tenenbaum; Avivit Brener; Marko Šimunović; Sophia D Sakka; Michal Nevo Shenker; Caroline Gb Passone; Irene Rutigliano; Davide Tinti; Clara Bonura; Silvana Caiulo; Anna Ruszala; Barbara Piccini; Dinesh Giri; Ronnie Stein; Ivana Rabbone; Patrizia Bruzzi; Jasna Šuput Omladič; Caroline Steele; Guglielmo Beccuti; Michal Yackobovitch-Gavan; Tadej Battelino; Thomas Danne; Eran Atlas; Moshe Phillip
Journal:  Diabetes Obes Metab       Date:  2018-07-18       Impact factor: 6.577

2.  Implications of the 21st Century Cures Act in Pediatrics.

Authors:  Natalie M Pageler; Emily C Webber; Dennis P Lund
Journal:  Pediatrics       Date:  2020-12-08       Impact factor: 7.124

3.  EHRs: The Challenge of Making Electronic Data Usable and Interoperable.

Authors:  Miriam Reisman
Journal:  P T       Date:  2017-09

4.  State of Type 1 Diabetes Management and Outcomes from the T1D Exchange in 2016-2018.

Authors:  Nicole C Foster; Roy W Beck; Kellee M Miller; Mark A Clements; Michael R Rickels; Linda A DiMeglio; David M Maahs; William V Tamborlane; Richard Bergenstal; Elizabeth Smith; Beth A Olson; Satish K Garg
Journal:  Diabetes Technol Ther       Date:  2019-01-18       Impact factor: 6.118

5.  Outcomes associated with a pediatric clinical diabetes network in Ontario: a population-based time-trend analysis.

Authors:  Meranda Nakhla; Elham Rahme; Marc Simard; Astrid Guttmann
Journal:  CMAJ Open       Date:  2017-07-24

6.  Improved access to subspecialist diabetes care by telemedicine: cost savings and care measures in the first two years of the FITE diabetes project.

Authors:  Toree H Malasanos; Julie B Burlingame; Lise Youngblade; Bhavin D Patel; Andrew B Muir
Journal:  J Telemed Telecare       Date:  2005       Impact factor: 6.184

7.  Relationship Between Clerical Burden and Characteristics of the Electronic Environment With Physician Burnout and Professional Satisfaction.

Authors:  Tait D Shanafelt; Lotte N Dyrbye; Christine Sinsky; Omar Hasan; Daniel Satele; Jeff Sloan; Colin P West
Journal:  Mayo Clin Proc       Date:  2016-06-27       Impact factor: 7.616

8.  The Digital/Virtual Diabetes Clinic: The Future Is Now-Recommendations from an International Panel on Diabetes Digital Technologies Introduction.

Authors:  Moshe Phillip; Richard M Bergenstal; Kelly L Close; Thomas Danne; Satish K Garg; Lutz Heinemann; Irl B Hirsch; Boris P Kovatchev; Lori M Laffel; Viswanathan Mohan; Christopher G Parkin; Tadej Battelino
Journal:  Diabetes Technol Ther       Date:  2020-09-28       Impact factor: 6.118

9.  Automated integration of continuous glucose monitor data in the electronic health record using consumer technology.

Authors:  Rajiv B Kumar; Nira D Goren; David E Stark; Dennis P Wall; Christopher A Longhurst
Journal:  J Am Med Inform Assoc       Date:  2016-03-27       Impact factor: 4.497

Review 10.  Improving Clinical Outcomes in Newly Diagnosed Pediatric Type 1 Diabetes: Teamwork, Targets, Technology, and Tight Control-The 4T Study.

Authors:  Priya Prahalad; Dessi P Zaharieva; Ananta Addala; Christin New; David Scheinker; Manisha Desai; Korey K Hood; David M Maahs
Journal:  Front Endocrinol (Lausanne)       Date:  2020-07-09       Impact factor: 5.555

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  3 in total

1.  Teamwork, Targets, Technology, and Tight Control in Newly Diagnosed Type 1 Diabetes: the Pilot 4T Study.

Authors:  Priya Prahalad; Victoria Y Ding; Dessi P Zaharieva; Ananta Addala; Ramesh Johari; David Scheinker; Manisha Desai; Korey Hood; David M Maahs
Journal:  J Clin Endocrinol Metab       Date:  2022-03-24       Impact factor: 5.958

Review 2.  Advancements and future directions in the teamwork, targets, technology, and tight control-the 4T study: improving clinical outcomes in newly diagnosed pediatric type 1 diabetes.

Authors:  Dessi P Zaharieva; Franziska K Bishop; David M Maahs
Journal:  Curr Opin Pediatr       Date:  2022-08-01       Impact factor: 2.893

3.  Algorithm-Enabled, Personalized Glucose Management for Type 1 Diabetes at the Population Scale: Prospective Evaluation in Clinical Practice.

Authors:  David Scheinker; Angela Gu; Joshua Grossman; Andrew Ward; Oseas Ayerdi; Daniel Miller; Jeannine Leverenz; Korey Hood; Ming Yeh Lee; David M Maahs; Priya Prahalad
Journal:  JMIR Diabetes       Date:  2022-06-06
  3 in total

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