Hang Zhang1, Hanmei Xu1, Lijuan Huang1, Yanping Wang1, Fang Deng2, Xiaolan Wang1, Xiaowei Tang1, Wo Wang3, Xia Fu1, Yuanmei Tao1, Li Yin4,5. 1. Mental Health Center, West China Hospital, Sichuan University, No. 28 Dianxin South Street, Sichuan, 610041, Chengdu, China. 2. The Fourth People's Hospital of Chengdu, Chengdu, 610036, Sichuan, China. 3. University-Town Hospital of Chongqing Medical University, 55 University Town Middle Road, Shapingba District, Chongqing, 400000, China. 4. Mental Health Center, West China Hospital, Sichuan University, No. 28 Dianxin South Street, Sichuan, 610041, Chengdu, China. yli009@163.com. 5. Institute for System Genetics, Frontiers Science Center for Disease-related Molecular Network, Chengdu, 610041, Sichuan, China. yli009@163.com.
Abstract
BACKGROUND: The Coronavirus Disease 2019 (COVID-19) pandemic continues to threaten the physical and mental health of people across the world. This study aimed to understand the psychological impact of this disease on adolescents with major depressive disorder (MDD) at 1 month after the start of the outbreak in China. METHODS: Using the Children's Impact of Event Scale (CRIES-13) questionnaire, we investigated the occurrence of posttraumatic stress disorder (PTSD) in two groups of adolescents: MDD patients who were in continuous antidepressant therapy and healthy controls. Total scores and factor subscores were compared between the two groups and subgroups stratified by sex and school grade. Logistic regression was used to identify variables associated with high total CRIES-13 scores. RESULTS: Compared to controls (n = 107), the MDD group (n = 90) had higher total CRIES-13 scores and a higher proportion with a total score ≥ 30. They also had a lower intrusion subscore and a higher arousal subscore. In the MDD group, males and females did not differ significantly in total CRIES-13 scores or factor subscores, but junior high school students had higher avoidance subscores than senior high school students. Logistic regression showed high total CRIES-13 scores to be associated with MDD and the experience of "flashbacks" or avoidance of traumatic memories associated with COVID-19. CONCLUSIONS: It is crucial to understand the psychological impact of COVID-19 on adolescents with MDD in China, especially females and junior high school students. Long-term monitoring of adolescents with a history of mental illness is required to further understand these impacts. TRIAL REGISTRATION: ChiCTR, ChiCTR2000033402 , Registered 31 May 2020.
BACKGROUND: The Coronavirus Disease 2019 (COVID-19) pandemic continues to threaten the physical and mental health of people across the world. This study aimed to understand the psychological impact of this disease on adolescents with major depressive disorder (MDD) at 1 month after the start of the outbreak in China. METHODS: Using the Children's Impact of Event Scale (CRIES-13) questionnaire, we investigated the occurrence of posttraumatic stress disorder (PTSD) in two groups of adolescents: MDDpatients who were in continuous antidepressant therapy and healthy controls. Total scores and factor subscores were compared between the two groups and subgroups stratified by sex and school grade. Logistic regression was used to identify variables associated with high total CRIES-13 scores. RESULTS: Compared to controls (n = 107), the MDD group (n = 90) had higher total CRIES-13 scores and a higher proportion with a total score ≥ 30. They also had a lower intrusion subscore and a higher arousal subscore. In the MDD group, males and females did not differ significantly in total CRIES-13 scores or factor subscores, but junior high school students had higher avoidance subscores than senior high school students. Logistic regression showed high total CRIES-13 scores to be associated with MDD and the experience of "flashbacks" or avoidance of traumatic memories associated with COVID-19. CONCLUSIONS: It is crucial to understand the psychological impact of COVID-19 on adolescents with MDD in China, especially females and junior high school students. Long-term monitoring of adolescents with a history of mental illness is required to further understand these impacts. TRIAL REGISTRATION: ChiCTR, ChiCTR2000033402 , Registered 31 May 2020.
Authors: G Kolaitis; J Kotsopoulos; J Tsiantis; S Haritaki; F Rigizou; L Zacharaki; E Riga; A Augoustatou; A Bimbou; N Kanari; M Liakopoulou; P Katerelos Journal: Eur Child Adolesc Psychiatry Date: 2003-12 Impact factor: 4.785
Authors: Sandra Carvalho; Catarina G Coelho; Bruno Kluwe-Schiavon; Juliana Magalhães; Jorge Leite Journal: Int J Environ Res Public Health Date: 2022-04-23 Impact factor: 4.614