| Literature DB >> 32405111 |
Wanjie Tang1, Tao Hu2, Baodi Hu3, Chunhan Jin4, Gang Wang5, Chao Xie6, Sen Chen7, Jiuping Xu8.
Abstract
BACKGROUND: When COVID-19 emerged in China in late 2019, most citizens were home-quarantined to prevent the spread of the virus. This study explored the prevalence of post-traumatic stress disorder (PTSD) and depression in a sample of home-quarantined college students to identify the psychological distress risk factors.Entities:
Keywords: COVID-19; Depression; PTSD; Sleep duration; Undergraduate
Mesh:
Year: 2020 PMID: 32405111 PMCID: PMC7217769 DOI: 10.1016/j.jad.2020.05.009
Source DB: PubMed Journal: J Affect Disord ISSN: 0165-0327 Impact factor: 6.533
Study Sample Demographic Characteristics (n=2485).
| N | % | |
|---|---|---|
| 2485 | 100 | |
| 16-19 | 1166 | 46.9 |
| 20-23 | 1183 | 47.6 |
| 24-27 | 136 | 5.5 |
| Male | 960 | 39.2 |
| Female | 1525 | 60.8 |
| Yes | 1061 | 42.7 |
| No | 1424 | 57.3 |
| 1st year(freshman) | 977 | 39.3 |
| 2nd year(sophomore) | 778 | 31.3 |
| 3rd year(junior) | 519 | 20.9 |
| 4th year(senior) | 211 | 8.5 |
| Home | 2260 | 90.9 |
| Dormitory | 195 | 7.8 |
| Other places | 30 | 1.3 |
| Yes | 343 | 13.8 |
| No | 2142 | 86.2 |
| Yes | 105 | 4.2 |
| No | 2380 | 95.8 |
| Yes | 1 | <0.1 |
| No | 2484 | >99.9 |
| Yes | 7 | 0.3 |
| No | 2478 | 99.7 |
| Yes | 6 | 0.2 |
| No | 2479 | 99.8 |
| Yes | 8 | 0.3 |
| No | 2477 | 99.7 |
| Yes | 244 | 9.8 |
| No | 2241 | 90.2 |
| Yes | 2 | <0.1 |
| No | 2483 | >99.9 |
Comparative analysis of the PCL-Total score and PHQ-9.
| Total score one month after the outbreak stratified by demographic, isolation time and sleep duration (n=2485) | ||||||
|---|---|---|---|---|---|---|
| 2.01 | 0.13 | 0.86 | 0.42 | |||
| 16-19 (n=1166) | 21.02±6.21 | 3.42±4.19 | ||||
| 20-23 (n=1183) | 21.34±6.09 | 3.56±4.03 | ||||
| 24-27 (n=136) | 22.04±6.97 | 3.86±4.24 | ||||
| 2.01 | 0.04 | 1.76 | 0.08 | |||
| Male (n=960) | 20.92±6.29 | 3.33±4.13 | ||||
| Female (n=1525) | 21.43±6.14 | 3.63±4.10 | ||||
| 5.73 | 0.02 | 0.83 | 0.40 | |||
| Yes (n=1061) | 21.53±6.43 | 3.43±4.12 | ||||
| No (n=1424) | 20.83±5.86 | 3.57±4.11 | ||||
| 1st year (n=977) | 20.85±5.94 | 3.31±3.98 | ||||
| 2nd year (n=778) | 21.15±6.02 | 3.47±4.15 | ||||
| 3rd year (n=519) | 21.21±5.76 | 3.45±3.89 | ||||
| 4th year (n=211) | 23.39±8.35 | 4.74±4.89 | ||||
| 1.49 | 0.23 | 0.21 | 0.81 | |||
| Home (n=2260) | 21.17±6.04 | 3.50±4.11 | ||||
| Dormitory (n=195) | 21.97±8.07 | 3.56±4.22 | ||||
| Other places (n=30) | 21.13±4.10 | 3.97±4.20 | ||||
| Yes (n=343) | 25.44±8.94 | 5.37±4.86 | ||||
| No (n=2142) | 20.56±5.35 | 3.21±3.90 | ||||
| 1.45 | 0.14 | |||||
| Yes (n=105) | 22.11±6.13 | 4.52±4.27 | ||||
| No (n=2380) | 21.19±6.20 | 3.47±4.10 | ||||
| Yes (n=244) | 23.15±7.81 | 4.88±4.61 | ||||
| No (n=2241) | 21.02±5.97 | 3.37±4.03 | ||||
| 0.58 | 0.68 | 1.04 | 0.39 | |||
| No (n=256) | 20.72±6.08 | 3.13±3.97 | ||||
| < 1 week (n=147) | 21.58±5.72 | 3.91±4.36 | ||||
| 1-2 weeks (n=242) | 21.21±5.77 | 3.66±4.06 | ||||
| 2 – 4 weeks (n=1704) | 21.28±6.27 | 3.53±4.10 | ||||
| >4 weeks (n=136) | 21.22±6.85 | 3.33±4.40 | ||||
| <6 hours (n=67) | 27.12±10.48 | 7.05±5.74 | ||||
| 6-7 hours (n=134) | 22.73±7.18 | 4.85±5.09 | ||||
| 7-8 hours (n=822) | 21.03±5.77 | 3.28±3.88 | ||||
| 8-9 hours (n=700) | 21.11±5.95 | 3.33±3.82 | ||||
| 9-10 hours (n=601) | 20.73±5.54 | 3.34±3.94 | ||||
| >10 hours (n=161) | 20.98±7.12 | 3.55±4.61 | ||||
PTSD and depression Multiple regression analysis (n = 2485).
| PTSD | Depression | |||||||
|---|---|---|---|---|---|---|---|---|
| Model | Unstandardized Coefficients | Standardized Coefficients | Unstandardized Coefficients | Standardized Coefficients | ||||
| B | Std. Error | Beta | Sig. | B | Std. Error | Beta | Sig. | |
| Gender | 0.14 | 0.26 | 0.01 | 0.60 | 0.01 | 0.18 | 0.01 | 0.99 |
| Only-child | 0.64 | 0.24 | 0.05 | 0.02 | 0.11 | 0.16 | 0.01 | 0.49 |
| University year | 0.51 | 0.13 | -0.27 | 0.09 | ||||
| People infected in their communities | 0.66 | 0.59 | 0.02 | 0.27 | 0.86 | 0.40 | 0.04 | 0.03 |
| Felt extreme fear | 4.78 | 0.35 | 2.07 | 0.24 | ||||
| Living in the worst-hit areas | 1.39 | 0.41 | 1.12 | 0.28 | ||||
| Sleep duration per night | -0.48 | 0.09 | -0.24 | 0.06 | ||||
Mediation analyses resultsa.
| Path | 95% CI | |||
|---|---|---|---|---|
| Exposure (X) → Sleep duration (M) → PTSD (Y) | ||||
| Total effect of X on Y | 2.375 | 0.207 | <0.001 | 1.968- 2.781 |
| Direct effect of X on Y | 2.271 | 0.204 | <0.001 | 1.871- 2.670 |
| Indirect effect of X on Y | 0.104 | 0.048 | <0.001 | 0.016- 0.204 |
| X → M | -0.118 | 0.044 | <0.001 | -0.204- -0.032 |
| M → Y | -0.881 | 0.093 | <0.001 | -1.063- -0.699 |
| Exposure (X) → Sleep duration (M) → depression(Y) | ||||
| Total effect of X on Y | 1.292 | 0.139 | <0.001 | 1.021-1.564 |
| Direct effect of X on Y | 1.227 | 0.137 | <0.001 | 0.959-1.495 |
| Indirect effect of X on Y | 0.065 | 0.030 | <0.001 | 0.010-0.126 |
| X → M | -0.118 | 0.044 | <0.001 | -0.204- -0.032 |
| M → Y | -0.552 | 0.062 | <0.001 | -0.674- -0.430 |
Bootstrap SEs and 95% CIs were calculated in the indirect effect
Abbreviations: PTSD, Posttraumatic stress disorder; SE, standard error; CI, confidence interval.