Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Growth and mechanobiology of the tendon-bone enthesis.

Literature DB >> 34362655

Growth and mechanobiology of the tendon-bone enthesis.

Abstract

Tendons are cable-like connective tissues that transfer both active and passive forces generated by skeletal muscle to bone. In the mature skeleton, the tendon-bone enthesis is an interfacial zone of transitional tissue located between two mechanically dissimilar tissues: compliant, fibrous tendon to rigid, dense mineralized bone. In this review, we focus on emerging areas in enthesis development related to its structure, function, and mechanobiology, as well as highlight established and emerging signaling pathways and physiological processes that influence the formation and adaptation of this important transitional tissue.

Entities: Chemical

Keywords: Enthesis; Fibrocartilage; Muscle loading; Tendon

Mesh：

Year: 2021 PMID： 34362655 PMCID： PMC8810906 DOI： 10.1016/j.semcdb.2021.07.015

Source DB: PubMed Journal: Semin Cell Dev Biol ISSN： 1084-9521 Impact factor: 7.727

142 in total

Review 1. Where tendons and ligaments meet bone: attachment sites ('entheses') in relation to exercise and/or mechanical load.

Authors: M Benjamin; H Toumi; J R Ralphs; G Bydder; T M Best; S Milz
Journal: J Anat Date: 2006-04 Impact factor: 2.610

2. Enthesis fibrocartilage cells originate from a population of Hedgehog-responsive cells modulated by the loading environment.

Authors: Andrea G Schwartz; Fanxin Long; Stavros Thomopoulos
Journal: Development Date: 2015-01-01 Impact factor: 6.868

3. Inhibition of Hif1α prevents both trauma-induced and genetic heterotopic ossification.

Authors: Shailesh Agarwal; Shawn Loder; Cameron Brownley; David Cholok; Laura Mangiavini; John Li; Christopher Breuler; Hsiao H Sung; Shuli Li; Kavitha Ranganathan; Joshua Peterson; Ronald Tompkins; David Herndon; Wenzhong Xiao; Dolrudee Jumlongras; Bjorn R Olsen; Thomas A Davis; Yuji Mishina; Ernestina Schipani; Benjamin Levi
Journal: Proc Natl Acad Sci U S A Date: 2015-12-31 Impact factor: 11.205

Review 4. Load transfer, damage, and failure in ligaments and tendons.

Authors: Jared L Zitnay; Jeffrey A Weiss
Journal: J Orthop Res Date: 2018-09-21 Impact factor: 3.494

Review 5. BMPs are mediators in tissue crosstalk of the regenerating musculoskeletal system.

Authors: Karen Ruschke; Christian Hiepen; Jessica Becker; Petra Knaus
Journal: Cell Tissue Res Date: 2012-02-12 Impact factor: 5.249

Review 6. The axolotl limb blastema: cellular and molecular mechanisms driving blastema formation and limb regeneration in tetrapods.

Authors: Catherine McCusker; Susan V Bryant; David M Gardiner
Journal: Regeneration (Oxf) Date: 2015-05-11

1. Upregulation of Runt related transcription factor 1 (RUNX1) contributes to tendon-bone healing after anterior cruciate ligament reconstruction using bone mesenchymal stem cells.

Authors: Kai Kang; Qian Geng; Lukuan Cui; Lijie Wu; Lei Zhang; Tong Li; Qian Zhang; Shijun Gao
Journal: J Orthop Surg Res Date: 2022-05-13 Impact factor: 2.677

1 in total

Growth and mechanobiology of the tendon-bone enthesis.

Review 1. Where tendons and ligaments meet bone: attachment sites ('entheses') in relation to exercise and/or mechanical load.

2. Enthesis fibrocartilage cells originate from a population of Hedgehog-responsive cells modulated by the loading environment.

3. Inhibition of Hif1α prevents both trauma-induced and genetic heterotopic ossification.

Review 4. Load transfer, damage, and failure in ligaments and tendons.

Review 5. BMPs are mediators in tissue crosstalk of the regenerating musculoskeletal system.

Review 6. The axolotl limb blastema: cellular and molecular mechanisms driving blastema formation and limb regeneration in tetrapods.

7. PTHrP regulates the modeling of cortical bone surfaces at fibrous insertion sites during growth.

8. Optogenetic activation of muscle contraction in vivo.

9. Metabolic factors in diffuse idiopathic skeletal hyperostosis - a review of clinical data.

10. Tough and tunable scaffold-hydrogel composite biomaterial for soft-to-hard musculoskeletal tissue interfaces.

1. Upregulation of Runt related transcription factor 1 (RUNX1) contributes to tendon-bone healing after anterior cruciate ligament reconstruction using bone mesenchymal stem cells.