Literature DB >> 3435073

Magnetic resonance imaging in multiple sclerosis: decreased signal in thalamus and putamen.

B P Drayer1, P Burger, B Hurwitz, D Dawson, J Cain, J Leong, R Herfkens, G A Johnson.   

Abstract

High-field strength (1.5 Tesla) magnetic resonance imaging in 15 patients with multiple and extensive white-matter lesions and clinically definite multiple sclerosis delineated a previously undescribed finding of abnormally decreased signal intensity on T2-weighted images in the thalamus and putamen. The decreased signal intensity (preferential decreased T2 relaxation time) is most likely to be related to abnormally increased iron accumulation causing local magnetic field heterogeneities.

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Year:  1987        PMID： 3435073     DOI： 10.1002/ana.410220418

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  13 in total

Review 1.  Pathogenic implications of iron accumulation in multiple sclerosis.

Authors:  Rachel Williams; Cassandra L Buchheit; Nancy E J Berman; Steven M LeVine
Journal:  J Neurochem       Date:  2011-11-11       Impact factor: 5.372

Review 2.  Imaging of multiple sclerosis: role in neurotherapeutics.

Authors:  Rohit Bakshi; Alireza Minagar; Zeenat Jaisani; Jerry S Wolinsky
Journal:  NeuroRx       Date:  2005-04

3.  Enhancing the ability of experimental autoimmune encephalomyelitis to serve as a more rigorous model of multiple sclerosis through refinement of the experimental design.

Authors:  Mitchell R Emerson; Ryan J Gallagher; Janet G Marquis; Steven M LeVine
Journal:  Comp Med       Date:  2009-04       Impact factor: 0.982

4.  Does signal-attenuation on high-field T2-weighted MRI of the brain reflect regional cerebral iron deposition? Observations on the relationship between regional cerebral water proton T2 values and iron levels.

Authors:  D J Brooks; P Luthert; D Gadian; C D Marsden
Journal:  J Neurol Neurosurg Psychiatry       Date:  1989-01       Impact factor: 10.154

5.  Increasing signal intensity within the dentate nucleus and globus pallidus on unenhanced T1W magnetic resonance images in patients with relapsing-remitting multiple sclerosis: correlation with cumulative dose of a macrocyclic gadolinium-based contrast agent, gadobutrol.

Authors:  Dragan A Stojanov; Aleksandra Aracki-Trenkic; Slobodan Vojinovic; Daniela Benedeto-Stojanov; Srdjan Ljubisavljevic
Journal:  Eur Radiol       Date:  2015-06-25       Impact factor: 5.315

6.  The callosal-septal interface lesion in multiple sclerosis: effect of sequence and imaging plane.

Authors:  A Jackson; J B Fitzgerald; J E Gillespie
Journal:  Neuroradiology       Date:  1993       Impact factor: 2.804

Review 7.  Gadolinium deposition within the dentate nucleus and globus pallidus after repeated administrations of gadolinium-based contrast agents-current status.

Authors:  Dragan Stojanov; Aleksandra Aracki-Trenkic; Daniela Benedeto-Stojanov
Journal:  Neuroradiology       Date:  2016-02-12       Impact factor: 2.804

Review 8.  Clinical and genetic delineation of neurodegeneration with brain iron accumulation.

Authors:  A Gregory; B J Polster; S J Hayflick
Journal:  J Med Genet       Date:  2008-11-03       Impact factor: 6.318

9.  Quantitative assessment of iron accumulation in the deep gray matter of multiple sclerosis by magnetic field correlation imaging.

Authors:  Y Ge; J H Jensen; H Lu; J A Helpern; L Miles; M Inglese; J S Babb; J Herbert; R I Grossman
Journal:  AJNR Am J Neuroradiol       Date:  2007-09-24       Impact factor: 3.825

10.  Regional grey matter atrophy in clinically isolated syndromes at presentation.

Authors:  R G Henry; M Shieh; D T Okuda; A Evangelista; M L Gorno-Tempini; D Pelletier
Journal:  J Neurol Neurosurg Psychiatry       Date:  2008-05-09       Impact factor: 10.154
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