Literature DB >> 3434594

Strengths and weaknesses in the intellectual functioning of males with fragile X syndrome.

E M Dykens1, R M Hodapp, J F Leckman.   

Abstract

The intellectual strengths and weaknesses of 14 boys and young men with fragile X syndrome were assessed using the Sequential, Simultaneous, and Achievement domains of the Kaufman Assessment Battery for Children. Sequential processing, auditory, visual and motoric short-term memory, and arithmetic skills emerged as significant areas of weakness. Significant strengths were found in perceptual closure, inference, and flexibility. These findings both extend and contradict previous research and show the importance of classifying research groups by etiology of retardation rather than by overall level of impairment.

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Year:  1987        PMID: 3434594

Source DB:  PubMed          Journal:  Am J Ment Defic        ISSN: 0002-9351


  19 in total

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2.  Use of emotional cues for lexical learning: a comparison of autism spectrum disorder and fragile X syndrome.

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3.  Language Development in Individuals with Fragile X Syndrome.

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Review 4.  Fragile X-associated disorders: a clinical overview.

Authors:  Anne Gallagher; Brian Hallahan
Journal:  J Neurol       Date:  2011-07-12       Impact factor: 4.849

5.  Fragile X syndrome.

Authors:  J Turk
Journal:  Arch Dis Child       Date:  1995-01       Impact factor: 3.791

6.  Trajectory of adaptive behavior in males with fragile X syndrome.

Authors:  E M Dykens; R M Hodapp; S I Ort; J F Leckman
Journal:  J Autism Dev Disord       Date:  1993-03

7.  Between-generation differences in ascertainment and penetrance: relevance to genetic hypotheses in fragile X.

Authors:  D Z Loesch; L J Sheffield; D A Hay
Journal:  Hum Genet       Date:  1993-06       Impact factor: 4.132

Review 8.  Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome.

Authors:  Elizabeth M Berry-Kravis; Lothar Lindemann; Aia E Jønch; George Apostol; Mark F Bear; Randall L Carpenter; Jacqueline N Crawley; Aurore Curie; Vincent Des Portes; Farah Hossain; Fabrizio Gasparini; Baltazar Gomez-Mancilla; David Hessl; Eva Loth; Sebastian H Scharf; Paul P Wang; Florian Von Raison; Randi Hagerman; Will Spooren; Sébastien Jacquemont
Journal:  Nat Rev Drug Discov       Date:  2017-12-08       Impact factor: 84.694

9.  Outcome measures for clinical trials in fragile X syndrome.

Authors:  Elizabeth Berry-Kravis; David Hessl; Leonard Abbeduto; Allan L Reiss; Andrea Beckel-Mitchener; Tiina K Urv
Journal:  J Dev Behav Pediatr       Date:  2013-09       Impact factor: 2.225

10.  Changing patterns of intellectual strengths and weaknesses in males with fragile X syndrome.

Authors:  R M Hodapp; E M Dykens; S I Ort; D G Zelinsky; J F Leckman
Journal:  J Autism Dev Disord       Date:  1991-12
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