Literature DB >> 34321414

Progress Toward the 90-90-90 HIV Targets in Zimbabwe and Identifying Those Left Behind.

Avi J Hakim1, Beth A Tippett Barr2, Steven Kinchen1, Godfrey Musuka3, Julius Manjengwa3, Shungu Munyati4, Lovemore Gwanzura4,5, Owen Mugurungi6, Getrude Ncube6, Suzue Saito3, Bharat S Parekh1, Hetal Patel1, Yen T Duong3, Elizabeth Gonese2, Katrina Sleeman1, Leala Ruangtragool2,7, Jessica Justman3, Amy Herman-Roloff2, Elizabeth Radin3.   

Abstract

OBJECTIVE: We present findings from the nationally representative Zimbabwe Population-based HIV Impact Assessment that characterize Zimbabwe's progress toward the Joint United Nations Programme on HIV/AIDS 90-90-90 targets.
DESIGN: We conducted a cross-sectional household survey.
METHODS: Consenting adults and children in the household were eligible to participate in Zimbabwe Population-based HIV Impact Assessment (October 2015-August 2016). Participants completed face-to-face interviews and provided blood for HIV, CD4, viral load, and syphilis testing. Viral load suppression (VLS) was defined as HIV RNA <1000 copies/mL. HIV-positive specimens were tested for the presence of selected antiretroviral drugs. Data were weighted. Analysis was restricted to HIV-positive adults aged 15-64 years.
RESULTS: We enrolled 11,098 men and 14,033 women aged 15-64 years. HIV prevalence was 14.1%. Of those living with HIV, 76.8% (95% confidence interval [CI]: 74.9 to 78.7) were aware of their HIV status or had detectable antiretroviral levels. Of these, 88.4% (95% CI: 87.1 to 89.7) were receiving antiretroviral therapy (ART), and of these people, 85.3% (95% CI: 83.4 to 87.1) had VLS. Male sex age 15-34 years and having 1 or more sexual partners were associated with being unaware of one's HIV-positive status. Age <50 years and not taking cotrimoxazole were associated with being less likely to be being both aware and taking ART. Male sex, age <50 years, and taking cotrimoxazole were associated with being on ART but not having VLS.
CONCLUSIONS: Zimbabwe has made great strides toward epidemic control. Focusing resources on case finding, particularly among men, people aged <35 years, and sexually active individuals can help Zimbabwe attain 90-90-90 targets.
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

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Year:  2021        PMID: 34321414      PMCID: PMC8526397          DOI: 10.1097/QAI.0000000000002772

Source DB:  PubMed          Journal:  J Acquir Immune Defic Syndr        ISSN: 1525-4135            Impact factor:   3.771


  21 in total

Review 1.  The disconnect between individual-level and population-level HIV prevention benefits of antiretroviral treatment.

Authors:  Stefan Baral; Amrita Rao; Patrick Sullivan; Nancy Phaswana-Mafuya; Daouda Diouf; Greg Millett; Helgar Musyoki; Elvin Geng; Sharmistha Mishra
Journal:  Lancet HIV       Date:  2019-07-19       Impact factor: 12.767

2.  Towards UNAIDS Fast-Track goals: targeting priority geographic areas for HIV prevention and care in Zimbabwe.

Authors:  Diego F Cuadros; Jingjing Li; Zindoga Mukandavire; Godfrey N Musuka; Adam J Branscum; Benn Sartorius; Owen Mugurungi; Frank Tanser
Journal:  AIDS       Date:  2019-02-01       Impact factor: 4.177

3.  Sustained Sexual Behavior Change After Acute HIV Diagnosis in Malawi.

Authors:  Katherine B Rucinski; Sarah E Rutstein; Kimberly A Powers; Dana K Pasquale; Ann M Dennis; Sam Phiri; Mina C Hosseinipour; Gift Kamanga; Dominic Nsona; Cecilia Massa; Irving F Hoffman; William C Miller; Audrey E Pettifor
Journal:  Sex Transm Dis       Date:  2018-11       Impact factor: 2.830

4.  Changes in sexual risk behavior before and after HIV seroconversion in Southern African women enrolled in a HIV prevention trial.

Authors:  Kartik K Venkatesh; Guy de Bruyn; Kenneth H Mayer; Helen Cheng; Kelly Blanchard; Gita Ramjee; Tsungai Chipato; Elizabeth W Triche; Nancy S Padian; Ariane van der Straten
Journal:  J Acquir Immune Defic Syndr       Date:  2011-08-15       Impact factor: 3.731

Review 5.  Retention in care among HIV-infected patients in resource-limited settings: emerging insights and new directions.

Authors:  Elvin H Geng; Denis Nash; Andrew Kambugu; Yao Zhang; Paula Braitstein; Katerina A Christopoulos; Winnie Muyindike; Mwebesa Bosco Bwana; Constantin T Yiannoutsos; Maya L Petersen; Jeffrey N Martin
Journal:  Curr HIV/AIDS Rep       Date:  2010-11       Impact factor: 5.071

Review 6.  Integrating and Interpreting Findings from the Latest Treatment as Prevention Trials.

Authors:  Marie A Brault; Donna Spiegelman; Salim S Abdool Karim; Sten H Vermund
Journal:  Curr HIV/AIDS Rep       Date:  2020-06       Impact factor: 5.071

7.  Unprotected sex following HIV testing among women in Uganda and Zimbabwe: short- and long-term comparisons with pre-test behaviour.

Authors:  Abigail Norris Turner; William C Miller; Nancy S Padian; Jay S Kaufman; Frieda M Behets; Tsungai Chipato; Francis A Mmiro; Robert A Salata; Charles S Morrison
Journal:  Int J Epidemiol       Date:  2009-04-06       Impact factor: 7.196

8.  Patient retention, clinical outcomes and attrition-associated factors of HIV-infected patients enrolled in Zimbabwe's National Antiretroviral Therapy Programme, 2007-2010.

Authors:  Tsitsi Mutasa-Apollo; Ray W Shiraishi; Kudakwashe C Takarinda; Janet Dzangare; Owen Mugurungi; Joseph Murungu; Abu Abdul-Quader; Celia J I Woodfill
Journal:  PLoS One       Date:  2014-01-29       Impact factor: 3.240

9.  Prevention of mother-to-child transmission of HIV Option B+ cascade in rural Tanzania: The One Stop Clinic model.

Authors:  Anna Gamell; Lameck Bonaventure Luwanda; Aneth Vedastus Kalinjuma; Leila Samson; Alex John Ntamatungiro; Maja Weisser; Winfrid Gingo; Marcel Tanner; Christoph Hatz; Emilio Letang; Manuel Battegay
Journal:  PLoS One       Date:  2017-07-12       Impact factor: 3.240

10.  Barriers to HIV service utilisation by people living with HIV in two provinces of Zimbabwe: Results from 2016 baseline assessment.

Authors:  Taurayi A Tafuma; Nyikadzino Mahachi; Chengetai Dziwa; Tafara Moga; Paul Baloyi; Gladys Muyambo; Auxilia Muchedzi; Tinashe Chimbidzikai; Getrude Ncube; Joseph Murungu; Tendai Nyagura; Katherine Lew
Journal:  South Afr J HIV Med       Date:  2018-08-09       Impact factor: 2.744

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