Literature DB >> 29870501

Sustained Sexual Behavior Change After Acute HIV Diagnosis in Malawi.

Katherine B Rucinski1, Sarah E Rutstein2, Kimberly A Powers1, Dana K Pasquale1, Ann M Dennis2, Sam Phiri3, Mina C Hosseinipour, Gift Kamanga4, Dominic Nsona3, Cecilia Massa4, Irving F Hoffman2, William C Miller5, Audrey E Pettifor1.   

Abstract

BACKGROUND: Identification of acute HIV infection (AHI) allows for important opportunities for HIV prevention through behavior change and biomedical intervention. Here, we evaluate changes in sexual risk behaviors among persons with AHI enrolled in a combined behavioral and biomedical intervention designed to reduce onward transmission of HIV.
METHODS: Participants were randomized to standard HIV counseling, a multisession behavioral intervention, or a multisession behavioral intervention plus antiretrovirals. Sexual behaviors were assessed periodically over 1 year.
RESULTS: Four weeks after diagnosis, the predicted probability of reporting multiple sexual partners decreased from 24% to 9%, and the probability of reporting unprotected sex decreased from 71% to 27%. These declines in sexual risk behaviors were sustained over follow-up irrespective of study arm.
CONCLUSIONS: Diagnosis of AHI alone may be sufficient to achieve immediate and sustained behavior change during this highly infectious period.

Entities:  

Mesh：

Year:  2018        PMID： 29870501      PMCID： PMC6179914          DOI： 10.1097/OLQ.0000000000000873

Source DB:  PubMed          Journal:  Sex Transm Dis        ISSN： 0148-5717            Impact factor:   2.830


  29 in total

1.  Continued high risk sexual behavior following diagnosis with acute HIV infection in South Africa and Malawi: implications for prevention.

Authors:  Audrey Pettifor; Catherine MacPhail; Amy Corneli; Jabu Sibeko; Gift Kamanga; Nora Rosenberg; William C Miller; Irving Hoffman; Helen Rees; Myron S Cohen
Journal:  AIDS Behav       Date:  2011-08

2.  Rapid, real-time detection of acute HIV infection in patients in Africa.

Authors:  Susan A Fiscus; Christopher D Pilcher; William C Miller; Kimberly A Powers; Irving F Hoffman; Matthew Price; David A Chilongozi; Clement Mapanje; Robert Krysiak; Syze Gama; Francis E A Martinson; Myron S Cohen
Journal:  J Infect Dis       Date:  2006-12-22       Impact factor: 5.226

3.  Acute HIV-1 infection in sub-Saharan Africa: a common occurrence overlooked.

Authors:  Kimberly A Powers; Myron S Cohen
Journal:  AIDS       Date:  2014-06-01       Impact factor: 4.177

4.  Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size.

Authors:  Vivek Jain; Wendy Hartogensis; Peter Bacchetti; Peter W Hunt; Hiroyu Hatano; Elizabeth Sinclair; Lorrie Epling; Tzong-Hae Lee; Michael P Busch; Joseph M McCune; Christopher D Pilcher; Frederick M Hecht; Steven G Deeks
Journal:  J Infect Dis       Date:  2013-07-12       Impact factor: 5.226

Review 5.  The detection of acute HIV infection.

Authors:  Myron S Cohen; Cynthia L Gay; Michael P Busch; Frederick M Hecht
Journal:  J Infect Dis       Date:  2010-10-15       Impact factor: 5.226

6.  Sexual partnership patterns in malawi: implications for HIV/STI transmission.

Authors:  Kimberly A Powers; Irving F Hoffman; Azra C Ghani; Mina C Hosseinipour; Christopher D Pilcher; Matthew A Price; Audrey E Pettifor; David A Chilongozi; Francis E A Martinson; Myron S Cohen; William C Miller
Journal:  Sex Transm Dis       Date:  2011-07       Impact factor: 2.830

7.  Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy.

Authors:  Tuan Le; Edwina J Wright; Davey M Smith; Weijing He; Gabriel Catano; Jason F Okulicz; Jason A Young; Robert A Clark; Douglas D Richman; Susan J Little; Sunil K Ahuja
Journal:  N Engl J Med       Date:  2013-01-17       Impact factor: 91.245

8.  Rapid and durable antiretroviral effect of the HIV-1 Integrase inhibitor raltegravir as part of combination therapy in treatment-naive patients with HIV-1 infection: results of a 48-week controlled study.

Authors:  Martin Markowitz; Bach-Yen Nguyen; Eduardo Gotuzzo; Fernando Mendo; Winai Ratanasuwan; Colin Kovacs; Guillermo Prada; Javier O Morales-Ramirez; Clyde S Crumpacker; Robin D Isaacs; Lucinda R Gilde; Hong Wan; Michael D Miller; Larissa A Wenning; Hedy Teppler
Journal:  J Acquir Immune Defic Syndr       Date:  2007-10-01       Impact factor: 3.731

9.  HIV transmission risk behavior among HIV-infected adults in Uganda: results of a nationally representative survey.

Authors:  Rebecca Bunnell; Alex Opio; Joshua Musinguzi; Wilford Kirungi; Paul Ekwaru; Vinod Mishra; Wolfgang Hladik; Jessica Kafuko; Elizabeth Madraa; Jonathan Mermin
Journal:  AIDS       Date:  2008-03-12       Impact factor: 4.177

Review 10.  Clinical and public health implications of acute and early HIV detection and treatment: a scoping review.

Authors:  Sarah E Rutstein; Jintanat Ananworanich; Sarah Fidler; Cheryl Johnson; Eduard J Sanders; Omar Sued; Asier Saez-Cirion; Christopher D Pilcher; Christophe Fraser; Myron S Cohen; Marco Vitoria; Meg Doherty; Joseph D Tucker
Journal:  J Int AIDS Soc       Date:  2017-06-28       Impact factor: 5.396
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  7 in total

1.  Human Immunodeficiency Virus (HIV)-1 Transmission Among Persons With Acute HIV-1 Infection in Malawi: Demographic, Behavioral, and Phylogenetic Relationships.

Authors:  Ann M Dennis; Myron S Cohen; Katherine B Rucinski; Sarah E Rutstein; Kimberly A Powers; Dana K Pasquale; Sam Phiri; Mina C Hosseinipour; Gift Kamanga; Dominic Nsona; Cecilia Massa; Irving F Hoffman; Audrey E Pettifor; William C Miller
Journal:  Clin Infect Dis       Date:  2019-08-16       Impact factor: 9.079

2.  Social and behavioural research prospects for sexually transmissible infection prevention in the era of advances in biomedical approaches.

Authors:  Matthew Hogben; Patricia J Dittus; Jami S Leichliter; Sevgi O Aral
Journal:  Sex Health       Date:  2020-04       Impact factor: 2.706

3.  Brief Report: Blood and Genital Fluid Viral Load Trajectories Among Treated and Untreated Persons With Acute HIV Infection in Malawi.

Authors:  Jane S Chen; Audrey E Pettifor; Julie A E Nelson; Sam Phiri; Dana K Pasquale; Wiza Kumwenda; Gift Kamanga; Mackenzie L Cottrell; Craig Sykes; Angela D M Kashuba; Gerald Tegha; Robert Krysiak; Isaac Thengolose; Myron S Cohen; Irving F Hoffman; William C Miller; Sarah E Rutstein
Journal:  J Acquir Immune Defic Syndr       Date:  2022-05-01       Impact factor: 3.771

4.  High rates of transmitted NNRTI resistance among persons with acute HIV infection in Malawi: implications for first-line dolutegravir scale-up.

Authors:  Sarah E Rutstein; Jane S Chen; Julie A E Nelson; Samuel Phiri; William C Miller; Mina C Hosseinipour
Journal:  AIDS Res Ther       Date:  2019-02-22       Impact factor: 2.250

5.  Characteristics and Sexual Risk Behavior of Men Who Never Tested for HIV in Zambia.

Authors:  Maureen Muchimba; Cosmas Zyambo
Journal:  Am J Mens Health       Date:  2021 Nov-Dec

6.  HIV Testing by Public Health Centers and Municipalities and New HIV Cases During the COVID-19 Pandemic in Japan.

Authors:  Keisuke Ejima; Yoshiki Koizumi; Nao Yamamoto; Molly Rosenberg; Christina Ludema; Ana I Bento; Daisuke Yoneoka; Seiichi Ichikawa; Daisuke Mizushima; Shingo Iwami
Journal:  J Acquir Immune Defic Syndr       Date:  2021-06-01       Impact factor: 3.771

7.  Progress Toward the 90-90-90 HIV Targets in Zimbabwe and Identifying Those Left Behind.

Authors:  Avi J Hakim; Beth A Tippett Barr; Steven Kinchen; Godfrey Musuka; Julius Manjengwa; Shungu Munyati; Lovemore Gwanzura; Owen Mugurungi; Getrude Ncube; Suzue Saito; Bharat S Parekh; Hetal Patel; Yen T Duong; Elizabeth Gonese; Katrina Sleeman; Leala Ruangtragool; Jessica Justman; Amy Herman-Roloff; Elizabeth Radin
Journal:  J Acquir Immune Defic Syndr       Date:  2021-11-01       Impact factor: 3.771
  7 in total

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