| Literature DB >> 34318371 |
Jane Ha1,2, Yeongkeun Kwon2,3, Sungsoo Park2,3.
Abstract
Bariatric surgery has been widely performed for the treatment of obesity and type 2 diabetes. Efforts have been made to investigate the mechanisms underlying the metabolic effects achieved by bariatric surgery and to identify candidates who will benefit from this surgery. Metabolomics, which includes comprehensive profiling of metabolites in biological samples, has been utilized for various disease entities to discover pathophysiological metabolic pathways and biomarkers predicting disease progression or prognosis. Over the last decade, metabolomic studies on patients undergoing bariatric surgery have identified significant biomarkers related to metabolic effects. This review describes the significance, progress, and challenges for the future of metabolomics in the area of bariatric surgery.Entities:
Keywords: Amino acid; Bariatric surgery; Metabolic surgery; Metabolites; Metabolomics
Year: 2021 PMID: 34318371 DOI: 10.1007/s11695-021-05566-9
Source DB: PubMed Journal: Obes Surg ISSN: 0960-8923 Impact factor: 4.129