Literature DB >> 34303522

New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine.

Di Yan1, Johann E Gudjonsson2, Stephanie Le3, Emanual Maverakis3, Olesya Plazyo2, Christopher Ritchlin4, Jose U Scher5, Roopesh Singh6, Nicole L Ward7, Stacie Bell8, Wilson Liao9.   

Abstract

Psoriasis is a chronic inflammatory condition characterized by systemic immune dysregulation. Over the past several years, advances in genetics, microbiology, immunology, and mouse models have revealed the complex interplay between the heritable and microenvironmental factors that drive the development of psoriatic inflammation. In the first of this two-part review series, the authors will discuss the newest insights into the pathogenesis of psoriatic disease and highlight how the evolution of these scientific fields has paved the way for a more personalized approach to psoriatic disease treatment.
Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

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Year:  2021        PMID： 34303522      PMCID： PMC8384663          DOI： 10.1016/j.jid.2021.02.764

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  182 in total

1.  Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis.

Authors:  Alexandros Onoufriadis; Michael A Simpson; Andrew E Pink; Paola Di Meglio; Catherine H Smith; Venu Pullabhatla; Jo Knight; Sarah L Spain; Frank O Nestle; A David Burden; Francesca Capon; Richard C Trembath; Jonathan N Barker
Journal:  Am J Hum Genet       Date:  2011-08-11       Impact factor: 11.025

2.  Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis.

Authors:  B J Nickoloff; T Wrone-Smith
Journal:  Am J Pathol       Date:  1999-07       Impact factor: 4.307

3.  Genetic Study on Small Insertions and Deletions in Psoriasis Reveals a Role in Complex Human Diseases.

Authors:  Qi Zhen; Zhenjun Yang; Wenjun Wang; Bao Li; Mingzhou Bai; Jing Wu; Huiyao Ge; Zirui Dong; Juan Shen; Huayang Tang; Silong Sun; Ying Qiu; Jinjin Xu; Xiaoxiao Qu; Ying Wang; Meihui Yi; Huaqing Hu; Yuanhong Xu; Hui Cheng; Bo Liang; Jinping Gao; Haojing Shao; Zhengwen Jiang; Qiang Gao; Liangdan Sun
Journal:  J Invest Dermatol       Date:  2019-05-10       Impact factor: 8.551

4.  Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci.

Authors:  David Ellinghaus; Eva Ellinghaus; Rajan P Nair; Philip E Stuart; Tõnu Esko; Andres Metspalu; Sophie Debrus; John V Raelson; Trilokraj Tejasvi; Majid Belouchi; Sarah L West; Jonathan N Barker; Sulev Kõks; Külli Kingo; Tobias Balschun; Orazio Palmieri; Vito Annese; Christian Gieger; H Erich Wichmann; Michael Kabesch; Richard C Trembath; Christopher G Mathew; Gonçalo R Abecasis; Stephan Weidinger; Susanna Nikolaus; Stefan Schreiber; James T Elder; Michael Weichenthal; Michael Nothnagel; Andre Franke
Journal:  Am J Hum Genet       Date:  2012-04-06       Impact factor: 11.025

5.  Psoriasis and HLA-Cw6.

Authors:  A Tiilikainen; A Lassus; J Karvonen; P Vartiainen; M Julin
Journal:  Br J Dermatol       Date:  1980-02       Impact factor: 9.302

Review 6.  Key role of macrophages in the pathogenesis of CD18 hypomorphic murine model of psoriasis.

Authors:  Honglin Wang; Thorsten Peters; Anca Sindrilaru; Karin Scharffetter-Kochanek
Journal:  J Invest Dermatol       Date:  2009-02-26       Impact factor: 8.551

7.  Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.

Authors:  Xianyong Yin; Hui Qi Low; Ling Wang; Yonghong Li; Eva Ellinghaus; Jiali Han; Xavier Estivill; Liangdan Sun; Xianbo Zuo; Changbing Shen; Caihong Zhu; Anping Zhang; Fabio Sanchez; Leonid Padyukov; Joseph J Catanese; Gerald G Krueger; Kristina Callis Duffin; Sören Mucha; Michael Weichenthal; Stephan Weidinger; Wolfgang Lieb; Jia Nee Foo; Yi Li; Karseng Sim; Herty Liany; Ishak Irwan; Yikying Teo; Colin T S Theng; Rashmi Gupta; Anne Bowcock; Philip L De Jager; Abrar A Qureshi; Paul I W de Bakker; Mark Seielstad; Wilson Liao; Mona Ståhle; Andre Franke; Xuejun Zhang; Jianjun Liu
Journal:  Nat Commun       Date:  2015-04-23       Impact factor: 14.919

8.  Efficacy and safety of faecal microbiota transplantation in patients with psoriatic arthritis: protocol for a 6-month, double-blind, randomised, placebo-controlled trial.

Authors:  Maja Skov Kragsnaes; Jens Kjeldsen; Hans Christian Horn; Heidi Lausten Munk; Finn Moeller Pedersen; Hanne Marie Holt; Jens Kristian Pedersen; Dorte Kinggaard Holm; Henning Glerup; Vibeke Andersen; Ulrich Fredberg; Karsten Kristiansen; Robin Christensen; Torkell Ellingsen
Journal:  BMJ Open       Date:  2018-04-27       Impact factor: 2.692

9.  Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.

Authors:  Rajan P Nair; Kristina Callis Duffin; Cynthia Helms; Jun Ding; Philip E Stuart; David Goldgar; Johann E Gudjonsson; Yun Li; Trilokraj Tejasvi; Bing-Jian Feng; Andreas Ruether; Stefan Schreiber; Michael Weichenthal; Dafna Gladman; Proton Rahman; Steven J Schrodi; Sampath Prahalad; Stephen L Guthery; Judith Fischer; Wilson Liao; Pui-Yan Kwok; Alan Menter; G Mark Lathrop; Carol A Wise; Ann B Begovich; John J Voorhees; James T Elder; Gerald G Krueger; Anne M Bowcock; Gonçalo R Abecasis
Journal:  Nat Genet       Date:  2009-01-25       Impact factor: 38.330
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  4 in total

Review 1.  Roles of Infection in Psoriasis.

Authors:  Shihui Zhou; Zhirong Yao
Journal:  Int J Mol Sci       Date:  2022-06-23       Impact factor: 6.208

Review 2.  Prevention and risk assessment of cardiovascular events in a population of patients with psoriasis and psoriatic arthritis.

Authors:  Robert Olszewski; Klaudia Ćwiklińska; Maria Maślińska; Brygida Kwiatkowska
Journal:  Reumatologia       Date:  2022-09-07

3.  Climatotherapy at the Dead Sea for psoriasis is a highly effective anti-inflammatory treatment in the short term: An immunohistochemical study.

Authors:  Thomas Emmanuel; Annita Petersen; Hannah Inez Houborg; Anders Benjamin Rønsholdt; Dorte Lybaek; Torben Steiniche; Anne Bregnhøj; Lars Iversen; Claus Johansen
Journal:  Exp Dermatol       Date:  2022-02-27       Impact factor: 4.511

4.  ARG1 and CXCL2 are potential biomarkers target for psoriasis patients.

Authors:  Huilin Wang; Wenjun Chen; Caihua Lie; Yijie Zhang; Jiajia Li; Jilong Meng; Nan Zhang
Journal:  Mol Pain       Date:  2022-04       Impact factor: 3.370
  4 in total

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