Literature DB >> 3429380

A study of the interaction of roxithromycin with theophylline and carbamazepine.

B Saint-Salvi1, D Tremblay, A Surjus, M A Lefebvre.   

Abstract

There have been reports of an interaction when theophylline and macrolides are given together, and also when carbamazepine is given with macrolides. We compared the kinetics of theophylline and carbamazepine, given alone and then in combination with roxithromycin. Roxithromycin had little effect on the pharmacokinetics of theophylline and none on carbamazepine, and roxithromycin can be given with either of the drugs without any need to alter the dose.

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Year:  1987        PMID： 3429380     DOI： 10.1093/jac/20.suppl_b.121

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  12 in total

1.  Pharmacokinetics of roxithromycin and influence of H2-blockers and antacids on gastrointestinal absorption.

Authors:  M Boeckh; H Lode; G Höffken; S Daeschlein; P Koeppe
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1992-05       Impact factor: 3.267

Review 2.  Clinical pharmacokinetic properties of the macrolide antibiotics. Effects of age and various pathophysiological states (Part II).

Authors:  P Periti; T Mazzei; E Mini; A Novelli
Journal:  Clin Pharmacokinet       Date:  1989-05       Impact factor: 6.447

Review 3.  Pharmacokinetic interactions between theophylline and other medication (Part II).

Authors:  R A Upton
Journal:  Clin Pharmacokinet       Date:  1991-02       Impact factor: 6.447

4.  Lack of effect of ponsinomycin on the plasma pharmacokinetics of theophylline.

Authors:  W Couet; I Ingrand; B Reigner; J Girault; J Bizouard; J B Fourtillan
Journal:  Eur J Clin Pharmacol       Date:  1989       Impact factor: 2.953

Review 5.  Importance of multi-p450 inhibition in drug-drug interactions: evaluation of incidence, inhibition magnitude, and prediction from in vitro data.

Authors:  Nina Isoherranen; Justin D Lutz; Sophie P Chung; Houda Hachad; Rene H Levy; Isabelle Ragueneau-Majlessi
Journal:  Chem Res Toxicol       Date:  2012-09-27       Impact factor: 3.739

Review 6.  Influence of endogenous and exogenous effectors on the pharmacokinetics of theophylline. Focus on biotransformation.

Authors:  U Tröger; F P Meyer
Journal:  Clin Pharmacokinet       Date:  1995-04       Impact factor: 6.447

7.  Interaction between roxithromycin and cyclosporin in heart transplant patients.

Authors:  E M Billaud; R Guillemain; N Fortineau; M D Kitzis; G Dreyfus; C Amrein; C Kreft-Jaïs; J M Husson; P Chrétien
Journal:  Clin Pharmacokinet       Date:  1990-12       Impact factor: 6.447

8.  A pharmacokinetic interaction between roxithromycin and midazolam.

Authors:  J T Backman; K Aranko; J J Himberg; K T Olkkola
Journal:  Eur J Clin Pharmacol       Date:  1994       Impact factor: 2.953

Review 9.  Macrolide antibacterials. Drug interactions of clinical significance.

Authors:  N A von Rosensteil; D Adam
Journal:  Drug Saf       Date:  1995-08       Impact factor: 5.606

Review 10.  Pharmacokinetic drug interactions of macrolides.

Authors:  P Periti; T Mazzei; E Mini; A Novelli
Journal:  Clin Pharmacokinet       Date:  1992-08       Impact factor: 6.447
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