Yuhui Zhu1, Somee Jeong1, Ming Wu2, Jin-Yi Zhou2, Zi-Yi Jin3, Ren-Qiang Han2, Jie Yang2, Xiao-Feng Zhang4, Xu-Shan Wang4, Ai-Ming Liu5, Xiao-Ping Gu5, Ming Su6, Xu Hu6, Zheng Sun7, Gang Li7, Su Yon Jung8,9, Liming Li10, Lina Mu11, Qing-Yi Lu12, Carlo La Vecchia13, Jin-Kou Zhao2, Zuo-Feng Zhang1,8,12. 1. Department of Epidemiology, Fielding School of Public Health, University of California at Los Angeles (UCLA), Los Angeles, California, USA. 2. Department of Non-communicable Chronic Disease Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu Province. 3. Department of Epidemiology, School of Public Health, Fudan University, Shanghai. 4. Ganyu County Center for Disease Control and Prevention, Ganyu. 5. Dafeng County Center for Disease Control and Prevention, Dafeng. 6. Chuzhou County Center for Disease Control and Prevention, Chuzhou. 7. Tongshan County Center for Disease Control and Prevention, Tongshan, Jiangsu Province, China. 8. Jonsson Comprehensive Cancer Center, UCLA. 9. School of Nursing, UCLA, Los Angeles, California, USA. 10. Department of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing, China. 11. Department of Social and Preventive Medicine, State University of New York at Buffalo, Buffalo, New York. 12. Center for Human Nutrition, Department of Medicine, UCLA David Geffen School of Medicine, University of California at Los Angeles (UCLA), Los Angeles, California, USA. 13. Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Abstract
OBJECTIVES: Dietary factors are of importance in the development of stomach cancer. This study aims to examine index-based dietary patterns associated with stomach cancer in a Chinese population. METHODS: Using data from a population-based case-control study conducted in Jiangsu Province, China, we included a total of 8432 participants (1900 stomach cancer cases and 6532 controls). Dietary data collected by food frequency questionnaire was evaluated by modified Chinese Healthy Eating Index-2016 (mCHEI-2016) and the US Healthy Eating Index-2015 (HEI-2015). Multiple logistic regression analyses were applied to examine the association of mCHEI-2016 and HEI-2015 with stomach cancer while adjusting for potential confounders. The possible interactions between mCHEI-2016 or HEI-2015 and established risk factors were explored. RESULTS: Among nonproxy interviews, after adjusting for potential confounding factors, a higher score of sodium, reflecting lower intake per day, was inversely associated with stomach cancer [odds ratio (OR), 0.95; 95% CI, 0.91-0.99 for mCHEI-2016; OR, 0.97; 95% CI, 0.94-0.99 for HEI-2015]. No clear associations with stomach cancer were identified for total scores of HEI-2015 (OR, 0.98; 95% CI, 0.87-1.10 with a 10-point increase, P trend = 0.98) and mCHEI-2016 (OR, 1.05; 95% CI, 0.94-1.17 with a 10-point increase, P trend = 0.22). However, the relation between stomach cancer and the mCHEI-2016 was modified by BMI, with a possible inverse association in normal-weight subjects. CONCLUSIONS: Our findings highlight that reduced intake of dietary sodium would prevent the development of stomach cancer. The data indicate a heterogeneity between normal weight and overweight's dietary factors in relation to stomach cancer.
OBJECTIVES: Dietary factors are of importance in the development of stomach cancer. This study aims to examine index-based dietary patterns associated with stomach cancer in a Chinese population. METHODS: Using data from a population-based case-control study conducted in Jiangsu Province, China, we included a total of 8432 participants (1900 stomach cancer cases and 6532 controls). Dietary data collected by food frequency questionnaire was evaluated by modified Chinese Healthy Eating Index-2016 (mCHEI-2016) and the US Healthy Eating Index-2015 (HEI-2015). Multiple logistic regression analyses were applied to examine the association of mCHEI-2016 and HEI-2015 with stomach cancer while adjusting for potential confounders. The possible interactions between mCHEI-2016 or HEI-2015 and established risk factors were explored. RESULTS: Among nonproxy interviews, after adjusting for potential confounding factors, a higher score of sodium, reflecting lower intake per day, was inversely associated with stomach cancer [odds ratio (OR), 0.95; 95% CI, 0.91-0.99 for mCHEI-2016; OR, 0.97; 95% CI, 0.94-0.99 for HEI-2015]. No clear associations with stomach cancer were identified for total scores of HEI-2015 (OR, 0.98; 95% CI, 0.87-1.10 with a 10-point increase, P trend = 0.98) and mCHEI-2016 (OR, 1.05; 95% CI, 0.94-1.17 with a 10-point increase, P trend = 0.22). However, the relation between stomach cancer and the mCHEI-2016 was modified by BMI, with a possible inverse association in normal-weight subjects. CONCLUSIONS: Our findings highlight that reduced intake of dietary sodium would prevent the development of stomach cancer. The data indicate a heterogeneity between normal weight and overweight's dietary factors in relation to stomach cancer.
Authors: Yanan Ma; Wanshui Yang; Tracey G Simon; Stephanie A Smith-Warner; Teresa T Fung; Jing Sui; Dawn Chong; Trang VoPham; Jeffrey A Meyerhardt; Deliang Wen; Edward L Giovannucci; Andrew T Chan; Xuehong Zhang Journal: Hepatology Date: 2019-03-05 Impact factor: 17.425
Authors: Carlos A González; Paula Jakszyn; Guillem Pera; Antonio Agudo; Sheila Bingham; Domenico Palli; Pietro Ferrari; Heiner Boeing; Giuseppe del Giudice; Mario Plebani; Fátima Carneiro; Gabriella Nesi; Franco Berrino; Carlotta Sacerdote; Rosario Tumino; Salvatore Panico; Göran Berglund; Henrik Simán; Olof Nyrén; Göran Hallmans; Carmen Martinez; Miren Dorronsoro; Aurelio Barricarte; Carmen Navarro; José R Quirós; Naomi Allen; Timothy J Key; Nicholas E Day; Jakob Linseisen; Gabriele Nagel; Manuela M Bergmann; Kim Overvad; Majken K Jensen; Anne Tjonneland; Anja Olsen; H Bas Bueno-de-Mesquita; Marga Ocke; Petra H M Peeters; Mattijs E Numans; Françoise Clavel-Chapelon; Marie-Christine Boutron-Ruault; Antonia Trichopoulou; Theodora Psaltopoulou; Dimitrios Roukos; Eiliv Lund; Bertrand Hemon; Rudolf Kaaks; Teresa Norat; Elio Riboli Journal: J Natl Cancer Inst Date: 2006-03-01 Impact factor: 13.506
Authors: Joshua Petimar; Stephanie A Smith-Warner; Teresa T Fung; Bernard Rosner; Andrew T Chan; Frank B Hu; Edward L Giovannucci; Fred K Tabung Journal: Am J Clin Nutr Date: 2018-11-01 Impact factor: 7.045
Authors: Wen-Qing Li; Yikyung Park; Jennifer W Wu; Jian-Song Ren; Alisa M Goldstein; Philip R Taylor; Albert R Hollenbeck; Neal D Freedman; Christian C Abnet Journal: Clin Gastroenterol Hepatol Date: 2013-04-13 Impact factor: 11.382